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| A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage FC Ledesma, SF El Khamisy, MC Zuma, K Osborn, KW Caldecott Nature 461 (7264), 674-678, 2009 | 456 | 2009 |
| A genetic map of the response to DNA damage in human cells M Olivieri, T Cho, A Álvarez-Quilón, K Li, MJ Schellenberg, ... Cell 182 (2), 481-496. e21, 2020 | 357 | 2020 |
| Smc5–Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination G De Piccoli, F Cortes-Ledesma, G Ira, J Torres-Rosell, S Uhle, S Farmer, ... Nature cell biology 8 (9), 1032-1034, 2006 | 234 | 2006 |
| Double‐strand breaks arising by replication through a nick are repaired by cohesin‐dependent sister‐chromatid exchange F Cortés‐Ledesma, A Aguilera EMBO reports 7 (9), 919-926, 2006 | 192 | 2006 |
| TDP2/TTRAP is the major 5′-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage Z Zeng, F Cortés-Ledesma, SF El Khamisy, KW Caldecott Journal of Biological Chemistry 286 (1), 403-409, 2011 | 174 | 2011 |
| TDP2–Dependent Non-Homologous End-Joining Protects against Topoisomerase II–Induced DNA Breaks and Genome Instability in Cells and In Vivo F Gómez-Herreros, R Romero-Granados, Z Zeng, A Alvarez-Quilon, ... PLoS genetics 9 (3), e1003226, 2013 | 170 | 2013 |
| ZATT (ZNF451)–mediated resolution of topoisomerase 2 DNA-protein cross-links MJ Schellenberg, JA Lieberman, A Herrero-Ruiz, LR Butler, JG Williams, ... Science 357 (6358), 1412-1416, 2017 | 154 | 2017 |
| TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function F Gómez-Herreros, JHM Schuurs-Hoeijmakers, M McCormack, ... Nature genetics 46 (5), 516-521, 2014 | 153 | 2014 |
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| The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange F Prado, F Cortés‐Ledesma, A Aguilera EMBO reports 5 (5), 497-502, 2004 | 129 | 2004 |
| Equal sister chromatid exchange is a major mechanism of double-strand break repair in yeast S González-Barrera, F Cortés-Ledesma, RE Wellinger, A Aguilera Molecular cell 11 (6), 1661-1671, 2003 | 129 | 2003 |
| ATM specifically mediates repair of double-strand breaks with blocked DNA ends A Alvarez-Quilón, A Serrano-Benítez, J Ariel Lieberman, C Quintero, ... Nature communications 5 (1), 3347, 2014 | 115 | 2014 |
| Mitotic recombination in Saccharomyces cerevisiae F Prado, F Cortes-Ledesma, P Huertas, A Aguilera Current genetics 42, 185-198, 2003 | 115 | 2003 |
| Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme W Feng, D Kawauchi, H Körkel-Qu, H Deng, E Serger, L Sieber, ... Nature communications 8 (1), 14758, 2017 | 114 | 2017 |
| APLF (C2orf13) is a novel component of poly (ADP-ribose) signaling in mammalian cells SL Rulten, F Cortes-Ledesma, L Guo, NJ Iles, KW Caldecott Molecular and cellular biology, 2008 | 107 | 2008 |
| Does tyrosyl DNA phosphodiesterase-2 play a role in hepatitis B virus genome repair? X Cui, R McAllister, R Boregowda, JA Sohn, FC Ledesma, KW Caldecott, ... PloS one 10 (6), e0128401, 2015 | 93 | 2015 |
| The Dot1 histone methyltransferase and the Rad9 checkpoint adaptor contribute to cohesin-dependent double-strand break repair by sister chromatid recombination in Saccharomyces … F Conde, E Refolio, V Cordon-Preciado, F Cortés-Ledesma, L Aragon, ... Genetics 182 (2), 437-446, 2009 | 76 | 2009 |
| Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication F Cortes-Ledesma, C Tous, A Aguilera Nucleic acids research 35 (19), 6560-6570, 2007 | 40 | 2007 |
| A Novel Yeast Mutation, rad52-L89F, Causes a Specific Defect in Rad51-Independent Recombination That Correlates With a Reduced Ability of Rad52-L89F to … F Cortés-Ledesma, F Malagón, A Aguilera Genetics 168 (1), 553-557, 2004 | 27 | 2004 |
