KRAS oncogene in non-small cell lung cancer: clinical perspectives on the treatment of an old target M Román, I Baraibar, I López, E Nadal, C Rolfo, S Vicent, I Gil-Bazo Molecular cancer 17, 1-14, 2018 | 334 | 2018 |
Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer I Pino, R Pıo, G Toledo, N Zabalegui, S Vicent, N Rey, MD Lozano, ... Lung cancer 41 (2), 131-143, 2003 | 233 | 2003 |
ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours S Vicent, JM Lopez-Picazo, G Toledo, MD Lozano, W Torre, ... British journal of cancer 90 (5), 1047-1052, 2004 | 229 | 2004 |
Mitogen-activated protein kinase phosphatase-1 is overexpressed in non-small cell lung cancer and is an independent predictor of outcome in patients S Vicent, M Garayoa, JM López-Picazo, MD Lozano, G Toledo, ... Clinical Cancer Research 10 (11), 3639-3649, 2004 | 186 | 2004 |
A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis D Ajona, S Ortiz-Espinosa, H Moreno, T Lozano, MJ Pajares, J Agorreta, ... Cancer discovery 7 (7), 694-703, 2017 | 184 | 2017 |
Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models S Vicent, R Chen, LC Sayles, C Lin, RG Walker, AK Gillespie, ... The Journal of clinical investigation 120 (11), 3940-3952, 2010 | 159 | 2010 |
A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma R Chen, P Khatri, PK Mazur, M Polin, Y Zheng, D Vaka, CD Hoang, ... Cancer research 74 (10), 2892-2902, 2014 | 157 | 2014 |
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer A Vallejo, N Perurena, E Guruceaga, PK Mazur, S Martinez-Canarias, ... Nature communications 8 (1), 14294, 2017 | 139 | 2017 |
Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16, activation of the DNA damage response pathway D Blanco, S Vicent, MF Fraga, I Fernandez-Garcia, J Freire, A Lujambio, ... Neoplasia 9 (10), 840-IN12, 2007 | 138 | 2007 |
Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for Clcf1 and Il-6 in non–small cell lung cancer in vivo S Vicent, LC Sayles, D Vaka, P Khatri, O Gevaert, R Chen, Y Zheng, ... Cancer research 72 (22), 5744-5756, 2012 | 124 | 2012 |
Twist1 Suppresses Senescence Programs and Thereby Accelerates and Maintains Mutant Kras-Induced Lung Tumorigenesis PT Tran, EH Shroff, TF Burns, S Thiyagarajan, ST Das, T Zabuawala, ... PLoS genetics 8 (5), e1002650, 2012 | 123 | 2012 |
A novel lung cancer signature mediates metastatic bone colonization by a dual mechanism S Vicent, D Luis-Ravelo, I Antón, I García-Tuñón, F Borrás-Cuesta, J Dotor, ... Cancer research 68 (7), 2275-2285, 2008 | 112 | 2008 |
CANCERTOOL: a visualization and representation interface to exploit cancer datasets AR Cortazar, V Torrano, N Martín-Martín, A Caro-Maldonado, L Camacho, ... Cancer research 78 (21), 6320-6328, 2018 | 93 | 2018 |
Altered expression of adhesion molecules and epithelial–mesenchymal transition in silica-induced rat lung carcinogenesis D Blanco, S Vicent, E Elizegi, I Pino, MF Fraga, M Esteller, U Saffiotti, ... Laboratory investigation 84 (8), 999-1012, 2004 | 87 | 2004 |
Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade D Ajona, S Ortiz-Espinosa, T Lozano, F Exposito, A Calvo, K Valencia, ... Nature Cancer 1 (1), 75-85, 2020 | 85 | 2020 |
Elevated NSD3 histone methylation activity drives squamous cell lung cancer G Yuan, NM Flores, S Hausmann, SM Lofgren, V Kharchenko, ... Nature 590 (7846), 504-508, 2021 | 82 | 2021 |
CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential RG Manzano, LM Montuenga, M Dayton, P Dent, I Kinoshita, S Vicent, ... Oncogene 21 (28), 4435-4447, 2002 | 78 | 2002 |
αCP-4, encoded by a putative tumor suppressor gene at 3p21, but not its alternative splice variant αCP-4a, is underexpressed in lung cancer R Pio, I Zudaire, I Pino, Z Castano, N Zabalegui, S Vicent, ... Cancer research 64 (12), 4171-4179, 2004 | 68 | 2004 |
Blockade of the complement C5a/C5aR1 axis impairs lung cancer bone metastasis by CXCL16-mediated effects D Ajona, C Zandueta, L Corrales, H Moreno, MJ Pajares, ... American journal of respiratory and critical care medicine 197 (9), 1164-1176, 2018 | 64 | 2018 |
MEK1/2 inhibition elicits regression of autochthonous lung tumors induced by KRASG12D or BRAFV600E CL Trejo, J Juan, S Vicent, A Sweet-Cordero, M McMahon Cancer research 72 (12), 3048-3059, 2012 | 57 | 2012 |