Elisa Passini
Elisa Passini
Department of Computer Science, University of Oxford
Dirección de correo verificada de cs.ox.ac.uk - Página principal
TítuloCitado porAño
Variability in cardiac electrophysiology: using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm
A Muszkiewicz, OJ Britton, P Gemmell, E Passini, C Sánchez, X Zhou, ...
Progress in biophysics and molecular biology 120 (1-3), 115-127, 2016
822016
Human in silico drug trials demonstrate higher accuracy than animal models in predicting clinical pro-arrhythmic cardiotoxicity
E Passini, OJ Britton, HR Lu, J Rohrbacher, AN Hermans, DJ Gallacher, ...
Frontiers in physiology 8, 668, 2017
682017
Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy
E Passini, A Mincholé, R Coppini, E Cerbai, B Rodriguez, S Severi, ...
Journal of molecular and cellular cardiology 96, 72-81, 2016
572016
Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop
B Rodriguez, A Carusi, N Abi-Gerges, R Ariga, O Britton, G Bub, ...
Ep Europace 18 (9), 1287-1298, 2015
312015
Phenotypic variability in LQT3 human induced pluripotent stem cell-derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach
M Paci, E Passini, S Severi, J Hyttinen, B Rodriguez
Heart Rhythm 14 (11), 1704-1712, 2017
252017
Recurrent intradialytic paroxysmal atrial fibrillation: hypotheses on onset mechanisms based on clinical data and computational analysis
A Vincenti, E Passini, P Fabbrini, MC Luise, S Severi, S Genovesi
Europace 16 (3), 396-404, 2014
242014
A population of in silico models to face the variability of human induced pluripotent stem cell-derived cardiomyocytes: the hERG block case study
M Paci, E Passini, S Severi, J Hyttinen, B Rodriguez
2016 Computing in Cardiology Conference (CinC), 1189-1192, 2016
82016
Human atrial cell models to analyse haemodialysis-related effects on cardiac electrophysiology: work in progress
E Passini, S Genovesi, S Severi
Computational and mathematical methods in medicine 2014, 2014
52014
Drug‐induced shortening of the electromechanical window is an effective biomarker for in silico prediction of clinical risk of arrhythmias
E Passini, C Trovato, P Morissette, F Sannajust, A Bueno‐Orovio, ...
British journal of pharmacology 176 (19), 3819-3833, 2019
42019
Extracellular calcium and l-type calcium current inactivation mechanisms: a computational study
E Passini, S Severi
Computing in Cardiology 2013, 839-842, 2013
42013
Computational analysis of head-down bed rest effects on cardiac action potential duration
E Passini, A Pellegrini, E Caiani, S Severi
Computing in Cardiology 2013, 357-360, 2013
32013
General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy
Z Li, GR Mirams, T Yoshinaga, BJ Ridder, X Han, JE Chen, ...
Clinical Pharmacology & Therapeutics 107 (1), 102-111, 2020
22020
Computational Analysis of Extracellular Calcium Effects on an Improved Human Ventricular Action Potential Model
E Passini, S Severi
Computing in Cardiology (CinC), 2012, 873-876, 2012
22012
In Silico Populations Optimized on Optogenetic Recordings Predict Drug Effects in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes
M Paci, E Passini, A Klimas, S Severi, J Hyttinen, B Rodriguez, ...
2018 Computing in Cardiology Conference (CinC) 45, 1-4, 2018
12018
Optimization of the O'Hara-Rudy Model of Human Ventricular Action Potential With Respect to Electrolyte Concentrations and Rate Dependence
C Bartolucci, E Passini, S Severi
2018 Computing in Cardiology Conference (CinC) 45, 1-4, 2018
12018
In silico modeling of human iPS cardiomyocytes: Effect of drugs and comparison to human adult cardiomyocytes
M Paci, E Passini, S Severi, J Hyttinen, B Rodriguez
Journal of Pharmacological and Toxicological Methods 88, 240-241, 2017
12017
Investigation of the presence and mechanisms of action potential alternans in hypertrophic cardiomyopathy
A Lyon, A Mincholé, E Passini, B Rodriguez
2017 Computing in Cardiology (CinC), 1-4, 2017
12017
Computational Modelling of Cardiac Electrophysiology: from Cell to Bedside
E Passini
alma, 2015
12015
Computational Analysis of Extracellular Calcium Effect on Action Potential Duration
E Passini, S Severi
Biophysical Journal 106 (2), 721a, 2014
12014
Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized Guinea pig assay
P Morissette, S Polak, A Chain, J Zhai, JP Imredy, MJ Wildey, J Travis, ...
Toxicology and Applied Pharmacology, 114883, 2020
2020
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