| Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain SJ Lee, SJ Kim, IK Kim, J Ko, CS Jeong, GH Kim, C Park, SO Kang, ... Journal of Biological Chemistry 278 (45), 44552-44559, 2003 | 293 | 2003 |
| Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states E Cotner-Gohara, IK Kim, M Hammel, JA Tainer, AE Tomkinson, ... Biochemistry 49 (29), 6165-6176, 2010 | 109 | 2010 |
| Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death JH Houl, Z Ye, CA Brosey, LPF Balapiti-Modarage, S Namjoshi, A Bacolla, ... Nature communications 10 (1), 5654, 2019 | 91 | 2019 |
| Structure of mammalian poly (ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element IK Kim, JR Kiefer, CMW Ho, RA Stegeman, S Classen, JA Tainer, ... Nature structural & molecular biology 19 (6), 653-656, 2012 | 84 | 2012 |
| Two DNA-binding and nick recognition modules in human DNA ligase III E Cotner-Gohara, IK Kim, AE Tomkinson, T Ellenberger Journal of biological chemistry 283 (16), 10764-10772, 2008 | 71 | 2008 |
| A quantitative assay reveals ligand specificity of the DNA scaffold repair protein XRCC1 and efficient disassembly of complexes of XRCC1 and the poly (ADP-ribose) polymerase 1 … IK Kim, RA Stegeman, CA Brosey, T Ellenberger Journal of Biological Chemistry 290 (6), 3775-3783, 2015 | 59 | 2015 |
| Crystal structure of the DNA‐binding domain of BldD, a central regulator of aerial mycelium formation in Streptomyces coelicolor A3(2) IK Kim, CJ Lee, MK Kim, JM Kim, JH Kim, HS Yim, SS Cha, SO Kang Molecular microbiology 60 (5), 1179-1193, 2006 | 34 | 2006 |
| Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining V Kukshal, IK Kim, GL Hura, AE Tomkinson, JA Tainer, T Ellenberger Nucleic acids research 43 (14), 7021-7031, 2015 | 30 | 2015 |
| Crystal structure of a new type of NADPH-dependent quinone oxidoreductase (QOR2) from Escherichia coli IK Kim, HS Yim, MK Kim, DW Kim, YM Kim, SS Cha, SO Kang Journal of molecular biology 379 (2), 372-384, 2008 | 29 | 2008 |
| 14-3-3 proteins restrain the Exo1 nuclease to prevent overresection X Chen, IK Kim, Y Honaker, SC Paudyal, WK Koh, M Sparks, S Li, ... Journal of Biological Chemistry 290 (19), 12300-12312, 2015 | 27 | 2015 |
| Structure of human ADP-ribosyl-acceptor hydrolase 3 bound to ADP-ribose reveals a conformational switch that enables specific substrate recognition Y Pourfarjam, J Ventura, I Kurinov, A Cho, J Moss, IK Kim Journal of Biological Chemistry 293 (32), 12350-12359, 2018 | 26 | 2018 |
| High resolution crystal structure of PedB: a structural basis for the classification of pediocin-like immunity proteins IK Kim, MK Kim, JH Kim, HS Yim, SS Cha, SO Kang BMC Structural Biology 7, 1-9, 2007 | 25 | 2007 |
| An atypical BRCT–BRCT interaction with the XRCC1 scaffold protein compacts human DNA ligase IIIα within a flexible DNA repair complex M Hammel, I Rashid, A Sverzhinsky, Y Pourfarjam, MS Tsai, T Ellenberger, ... Nucleic acids research 49 (1), 306-321, 2021 | 22 | 2021 |
| Crystal structure of filamentous aggregates of human DJ-1 formed in an inorganic phosphate-dependent manner SS Cha, HI Jung, H Jeon, YJ An, IK Kim, S Yun, HJ Ahn, KC Chung, ... Journal of biological chemistry 283 (49), 34069-34075, 2008 | 20 | 2008 |
| Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly CS Yang, K Jividen, T Kamata, N Dworak, L Oostdyk, B Remlein, ... Nature Communications 12 (1), 2705, 2021 | 19 | 2021 |
| Poly (ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities A Cheruiyot, SC Paudyal, IK Kim, M Sparks, T Ellenberger, ... DNA repair 35, 106-115, 2015 | 19 | 2015 |
| PARG has a robust endo-glycohydrolase activity that releases protein-free poly (ADP-ribose) chains Y Pourfarjam, S Kasson, L Tran, C Ho, S Lim, IK Kim Biochemical and Biophysical Research Communications 527 (3), 818-823, 2020 | 17 | 2020 |
| CbiX-homologous protein (CbiXhp), a metal-binding protein, from Streptomyces seoulensis is involved in expression of nickel-containing superoxide dismutase IK Kim, YI Yim, YM Kim, JW Lee, HS Yim, SO Kang FEMS microbiology letters 228 (1), 21-26, 2003 | 16 | 2003 |
| Reconstitution and functional characterization of SARS-CoV-2 proofreading complex Z Ma, Y Pourfarjam, IK Kim Protein expression and purification 185, 105894, 2021 | 13 | 2021 |
| Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes S Kasson, N Dharmapriya, IK Kim Plos one 16 (6), e0254022, 2021 | 9 | 2021 |
John TainerDirector of Structural Biology, Professor at MD Anderson Cancer Center & Lawrence Berkeley LabVerified email at mdanderson.org
