Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers S Muro, C Garnacho, JA Champion, J Leferovich, C Gajewski, ... Molecular therapy 16 (8), 1450-1458, 2008 | 647 | 2008 |
Oxygen microscopy by two‐photon‐excited phosphorescence OS Finikova, AY Lebedev, A Aprelev, T Troxler, F Gao, C Garnacho, ... ChemPhysChem 9 (12), 1673-1679, 2008 | 269 | 2008 |
Timing of adequate antibiotic therapy is a greater determinant of outcome than are TNF and IL-10 polymorphisms in patients with sepsis J Garnacho-Montero, T Aldabo-Pallas, C Garnacho-Montero, A Cayuela, ... Critical care 10, 1-12, 2006 | 234 | 2006 |
Delivery of acid sphingomyelinase in normal and niemann-pick disease mice using intercellular adhesion molecule-1-targeted polymer nanocarriers C Garnacho, R Dhami, E Simone, T Dziubla, J Leferovich, EH Schuchman, ... Journal of Pharmacology and Experimental Therapeutics 325 (2), 400-408, 2008 | 122 | 2008 |
Lack of Pwcr1/MBII-85 snoRNA is critical for neonatal lethality in Prader–Willi syndrome mouse models F Ding, Y Prints, MS Dhar, DK Johnson, C Garnacho–Montero, ... Mammalian genome 16, 424-431, 2005 | 117 | 2005 |
Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease J Hsu, D Serrano, T Bhowmick, K Kumar, Y Shen, YC Kuo, C Garnacho, ... Journal of controlled release 149 (3), 323-331, 2011 | 111 | 2011 |
Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes C Garnacho, SM Albelda, VR Muzykantov, S Muro Journal of Controlled Release 130 (3), 226-233, 2008 | 92 | 2008 |
Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor J Papademetriou, C Garnacho, D Serrano, T Bhowmick, EH Schuchman, ... Journal of inherited metabolic disease 36, 467-477, 2013 | 70 | 2013 |
Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium D Serrano, T Bhowmick, R Chadha, C Garnacho, S Muro Arteriosclerosis, thrombosis, and vascular biology 32 (5), 1178-1185, 2012 | 63 | 2012 |
RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1 C Garnacho, V Shuvaev, A Thomas, L McKenna, J Sun, M Koval, ... Blood, The Journal of the American Society of Hematology 111 (6), 3024-3033, 2008 | 56 | 2008 |
In vivo performance of polymer nanocarriers dually-targeted to epitopes of the same or different receptors IT Papademetriou, C Garnacho, EH Schuchman, S Muro Biomaterials 34 (13), 3459-3466, 2013 | 54 | 2013 |
A comparative study on the alterations of endocytic pathways in multiple lysosomal storage disorders J Rappaport, RL Manthe, M Solomon, C Garnacho, S Muro Molecular pharmaceutics 13 (2), 357-368, 2016 | 52 | 2016 |
A fibrinogen-derived peptide provides intercellular adhesion molecule-1-specific targeting and intraendothelial transport of polymer nanocarriers in human cell cultures and mice C Garnacho, D Serrano, S Muro Journal of Pharmacology and Experimental Therapeutics 340 (3), 638-647, 2012 | 50 | 2012 |
Intracellular drug delivery: mechanisms for cell entry C Garnacho Current pharmaceutical design 22 (9), 1210-1226, 2016 | 36 | 2016 |
Enhanced delivery and effects of acid sphingomyelinase by ICAM-1-targeted nanocarriers in type B Niemann-Pick disease mice C Garnacho, R Dhami, M Solomon, EH Schuchman, S Muro Molecular Therapy 25 (7), 1686-1696, 2017 | 32 | 2017 |
Genetic variants of the MBL2 gene are associated with mortality in pneumococcal sepsis J Garnacho-Montero, E García-Cabrera, R Jiménez-Álvarez, ... Diagnostic microbiology and infectious disease 73 (1), 39-44, 2012 | 28 | 2012 |
Clathrin-Mediated Endocytosis Is Impaired in Type A–B Niemann–Pick Disease Model Cells and Can Be Restored by ICAM-1-Mediated Enzyme Replacement J Rappaport, C Garnacho, S Muro Molecular pharmaceutics 11 (8), 2887-2895, 2014 | 27 | 2014 |
Altered clathrin-independent endocytosis in type A Niemann-Pick disease cells and rescue by ICAM-1-targeted enzyme delivery J Rappaport, RL Manthe, C Garnacho, S Muro Molecular pharmaceutics 12 (5), 1366-1376, 2015 | 16 | 2015 |
Comparative study of the primary cilia in thyrocytes of adult mammals JC Utrilla, F Gordillo‐Martínez, A Gómez‐Pascual, JM Fernández‐Santos, ... Journal of Anatomy 227 (4), 550-560, 2015 | 14 | 2015 |
Expression of hypothalamic regulatory peptides in thyroid C cells of different mammals JC Utrilla, J Morillo-Bernal, F Gordillo-Martínez, R García-Marín, ... General and comparative endocrinology 187, 6-14, 2013 | 14 | 2013 |