Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy F Liu, X Yang, M Geng, M Huang Acta pharmaceutica sinica B 8 (4), 552-562, 2018 | 395 | 2018 |
Molecularly targeted cancer therapy: some lessons from the past decade M Huang, A Shen, J Ding, M Geng Trends in pharmacological sciences 35 (1), 41-50, 2014 | 376 | 2014 |
Terpenoids: natural products for cancer therapy M Huang, JJ Lu, MQ Huang, JL Bao, XP Chen, YT Wang Expert opinion on investigational drugs 21 (12), 1801-1818, 2012 | 357 | 2012 |
Natural products in cancer therapy: Past, present and future M Huang, JJ Lu, J Ding Natural products and bioprospecting 11 (1), 5-13, 2021 | 319 | 2021 |
Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype JM Kim, K Parmar, M Huang, DM Weinstock, CA Ruit, JL Kutok, ... Developmental cell 16 (2), 314-320, 2009 | 254 | 2009 |
Targeting epigenetic crosstalk as a therapeutic strategy for EZH2-aberrant solid tumors X Huang, J Yan, M Zhang, Y Wang, Y Chen, X Fu, R Wei, X Zheng, Z Liu, ... Cell 175 (1), 186-199. e19, 2018 | 182 | 2018 |
Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells H Mistry, G Hsieh, SJ Buhrlage, M Huang, E Park, GD Cuny, I Galinsky, ... Molecular cancer therapeutics 12 (12), 2651-2662, 2013 | 181 | 2013 |
Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation Q Lian, J Xu, S Yan, M Huang, H Ding, X Sun, A Bi, J Ding, B Sun, ... Cell research 27 (6), 784-800, 2017 | 174 | 2017 |
The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response M Huang, JM Kim, B Shiotani, K Yang, L Zou, AD D'Andrea Molecular cell 39 (2), 259-268, 2010 | 166 | 2010 |
Extensive Crosstalk between O-GlcNAcylation and Phosphorylation Regulates Akt Signaling S Wang, X Huang, D Sun, X Xin, Q Pan, S Peng, Z Liang, C Luo, Y Yang, ... PloS one 7 (5), e37427, 2012 | 147 | 2012 |
Feedback activation of leukemia inhibitory factor receptor limits response to histone deacetylase inhibitors in breast cancer H Zeng, J Qu, N Jin, J Xu, C Lin, Y Chen, X Yang, X He, S Tang, X Lan, ... Cancer cell 30 (3), 459-473, 2016 | 131 | 2016 |
Chimmitecan, a Novel 9-Substituted Camptothecin, with Improved Anticancer Pharmacologic Profiles In vitro and In vivo M Huang, H Gao, Y Chen, H Zhu, Y Cai, X Zhang, Z Miao, H Jiang, ... Clinical cancer research 13 (4), 1298-1307, 2007 | 125 | 2007 |
Aspirin inhibits cancer metastasis and angiogenesis via targeting heparanase X Dai, J Yan, X Fu, Q Pan, D Sun, Y Xu, J Wang, L Nie, L Tong, A Shen, ... Clinical Cancer Research 23 (20), 6267-6278, 2017 | 106 | 2017 |
The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma J Ai, Q Tang, Y Wu, Y Xu, T Feng, R Zhou, Y Chen, X Gao, Q Zhu, X Yue, ... Journal of the National Cancer Institute 103 (22), 1696-1712, 2011 | 98 | 2011 |
Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins M Huang, ZH Miao, H Zhu, YJ Cai, W Lu, J Ding Molecular cancer therapeutics 7 (6), 1440-1449, 2008 | 96 | 2008 |
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer N Jin, A Bi, X Lan, J Xu, X Wang, Y Liu, T Wang, S Tang, H Zeng, Z Chen, ... Nature communications 10 (1), 2701, 2019 | 94 | 2019 |
Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase HR Lu, H Zhu, M Huang, Y Chen, YJ Cai, ZH Miao, JS Zhang, J Ding Molecular pharmacology 68 (4), 983-994, 2005 | 91 | 2005 |
R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II H Zhu, M Huang, F Yang, Y Chen, ZH Miao, XH Qian, YF Xu, YX Qin, ... Molecular cancer therapeutics 6 (2), 484-495, 2007 | 88 | 2007 |
Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents Y Kee, M Huang, S Chang, LA Moreau, E Park, PG Smith, AD D'Andrea Molecular Cancer Research 10 (3), 369-377, 2012 | 80 | 2012 |
O-GlcNAcylation of cofilin promotes breast cancer cell invasion X Huang, Q Pan, D Sun, W Chen, A Shen, M Huang, J Ding, M Geng Journal of Biological Chemistry 288 (51), 36418-36425, 2013 | 77 | 2013 |