Bacterial histidine kinases as novel antibacterial drug targets AE Bem, N Velikova, MT Pellicer, P Baarlen, A Marina, JM Wells ACS chemical biology 10 (1), 213-224, 2015 | 198 | 2015 |
Putative histidine kinase inhibitors with antibacterial effect against multi-drug resistant clinical isolates identified by in vitro and in silico screens N Velikova, S Fulle, AS Manso, M Mechkarska, P Finn, JM Conlon, ... Scientific reports 6 (1), 26085, 2016 | 50 | 2016 |
Evaluation of Galleria mellonella larvae for studying the virulence of Streptococcus suis N Velikova, K Kavanagh, JM Wells BMC microbiology 16, 1-9, 2016 | 45 | 2016 |
Broadening the antibacterial spectrum of histidine kinase autophosphorylation inhibitors via the use of ε-poly-L-lysine capped mesoporous silica-based nanoparticles N Velikova, N Mas, L Miguel-Romero, L Polo, E Stolte, E Zaccaria, R Cao, ... Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), 569-581, 2017 | 27 | 2017 |
Altered ivermectin pharmacology and defective visual system in Drosophila mutants for histamine receptor HCLB S Yusein, N Velikova, P Kupenova, R Hardie, A Wolstenholme, ... Invertebrate neuroscience 8, 211-222, 2008 | 22 | 2008 |
WalK, the path towards new antibacterials with low potential for resistance development N Velikova, AE Bem, P van Baarlen, JM Wells, A Marina ACS Medicinal Chemistry Letters 4 (10), 891-894, 2013 | 21 | 2013 |
Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential NGJ Oliveira, MH Cardoso, N Velikova, M Giesbers, JM Wells, ... Scientific Reports 10 (1), 9127, 2020 | 19 | 2020 |
An acidic model pro-peptide affects the secondary structure, membrane interactions and antimicrobial activity of a crotalicidin fragment NGO Júnior, MH Cardoso, ES Cândido, D van den Broek, N de Lange, ... Scientific Reports 8 (1), 11127, 2018 | 13 | 2018 |
Bacterial histidine kinases as novel antibacterial drug targets. ACS Chem Biol 10: 213–224 AE Bem, N Velikova, MT Pellicer, P Baarlen, A Marina, JM Wells | 11 | 2015 |
Rationale and prospects of targeting bacterial two-component systems for antibacterial treatment of cystic fibrosis patients N Velikova, J M Wells Current Drug Targets 18 (6), 687-695, 2017 | 4 | 2017 |
Synthesis and SAR of phenylazoles, active against Staphylococcus aureus Newman VV Solomin, BF Ciruelos, N Velikova, J Wells, M Albanese, A Adhav, ... Chemistry of Heterocyclic Compounds 58 (12), 737-748, 2022 | 3 | 2022 |
The VraSR regulatory system contributes to virulence in Streptococcus suis via resistance to innate immune defenses N Velikova Virulence 9 (1), 681-682, 2018 | 1 | 2018 |
Histidine kinase inhibitors with antibacterial activity A Marina, N Velikova, P Finn, S Fulle, JM Wells | 1 | 2016 |
Repurposing Hsp90 inhibitors as antimicrobials targeting two-component systems identifies compounds leading to loss of bacterial membrane integrity BM Fernandez-Ciruelos, M Albanese, A Adhav, V Solomin, ... bioRxiv, 2023.12. 13.571547, 2023 | | 2023 |
Use of 3, 4-diarylpyrazoles as antibacterial agents J Wells, N Velikova EP Patent 3,827,825, 2021 | | 2021 |
Inhibidores de la histidina quinasa con actividad antibacteriana A Marina, N Velikova, P Finn, S Fulle, JM Wells | | 2016 |
Histidine kinase inhibitors with antibacterial activity A Marina Moreno, NR Velikova, P Finn, S Fulle, JM Wells | | 2016 |
HISTIDINE-KINASE INHIBITORS WITH BROAD-SPECTRUM ANTIBACTERIAL EFFECT IDENTIFIED BY FRAGMENT-BASED SCREENS N Velikova, S Fulle, AS Manso, M Mechkarska, N Taverne, P Finn, ... Discovery of Inhibitors of Bacterial Histidine Kinases, 67, 2014 | | 2014 |
Discovery of inhibitors of bacterial histidine kinases N Velikova PQDT-Global, 2014 | | 2014 |
STAPHYLOCOCCUS EPIDERMIDIS N Velikova, S Fulle, AS Manso, N Taverne, M Mechkarska, JM Conlon, ... Discovery of Inhibitors of Bacterial Histidine Kinases, 31, 2014 | | 2014 |