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Gregory T Tietjen
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A holistic approach to targeting disease with polymeric nanoparticles
CJ Cheng, GT Tietjen, JK Saucier-Sawyer, WM Saltzman
Nature reviews Drug discovery 14 (4), 239-247, 2015
4692015
Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys
GT Tietjen, SA Hosgood, J DiRito, J Cui, D Deep, E Song, JR Kraehling, ...
Science translational medicine 9 (418), eaam6764, 2017
1292017
Focus on fundamentals: achieving effective nanoparticle targeting
GT Tietjen, LG Bracaglia, WM Saltzman, JS Pober
Trends in molecular medicine 24 (7), 598-606, 2018
1022018
Surface chemistry governs cellular tropism of nanoparticles in the brain
E Song, A Gaudin, AR King, YE Seo, HW Suh, Y Deng, J Cui, GT Tietjen, ...
Nature communications 8 (1), 15322, 2017
912017
A Molecular Mechanism for Differential Recognition of Membrane Phosphatidylserine by the Immune Regulatory Receptor Tim4
GT Tietjen, Z Gong, CH Chen, E Vargas, JE Crooks, KD Cao, CTR Heffern, ...
Biophysical Journal 106 (2), 17a, 2014
912014
Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells
J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li, GT Tietjen, G Tellides, ...
Nature Communications 8 (1), 191, 2017
892017
The future of marginal kidney repair in the context of normothermic machine perfusion
JR DiRito, SA Hosgood, GT Tietjen, ML Nicholson
American Journal of Transplantation 18 (10), 2400-2408, 2018
752018
Quantitating endosomal escape of a library of polymers for mRNA delivery
Y Jiang, Q Lu, Y Wang, E Xu, A Ho, P Singh, Y Wang, Z Jiang, F Yang, ...
Nano letters 20 (2), 1117-1123, 2020
692020
Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys
JR DiRito, SA Hosgood, M Reschke, C Albert, LG Bracaglia, ...
American Journal of Transplantation 21 (1), 161-173, 2021
552021
A “top-down” approach to actuate poly (amine-co-ester) terpolymers for potent and safe mRNA delivery
Y Jiang, A Gaudin, J Zhang, T Agarwal, E Song, AC Kauffman, GT Tietjen, ...
Biomaterials 176, 122-130, 2018
532018
Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro
N Kosyakova, DD Kao, M Figetakis, F López-Giráldez, S Spindler, ...
NPJ Regenerative medicine 5 (1), 1, 2020
462020
Cellular recovery after prolonged warm ischaemia of the whole body
D Andrijevic, Z Vrselja, T Lysyy, S Zhang, M Skarica, A Spajic, D Dellal, ...
Nature 608 (7922), 405-412, 2022
372022
Nanomedicine gets personal
GT Tietjen, WM Saltzman
Science translational medicine 7 (314), 314fs47-314fs47, 2015
372015
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes
C Fang, TD Manes, L Liu, K Liu, L Qin, G Li, Z Tobiasova, ...
Nature communications 10 (1), 2247, 2019
322019
Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression
J Merola, M Reschke, RW Pierce, L Qin, S Spindler, T Baltazar, TD Manes, ...
JCI insight 4 (20), 2019
272019
Poly (amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver
J Cui, AS Piotrowski-Daspit, J Zhang, M Shao, LG Bracaglia, T Utsumi, ...
Journal of controlled release 304, 259-267, 2019
272019
Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2, 3-dioxygenase 1
R Liu, J Merola, TD Manes, L Qin, GT Tietjen, F López-Giráldez, ...
JCI insight 3 (5), 2018
182018
Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins
D Kerr, GT Tietjen, Z Gong, E Tajkhorshid, EJ Adams, KYC Lee
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (10), 2126-2133, 2018
172018
Coupling X-ray reflectivity and in silico binding to yield dynamics of membrane recognition by Tim1
GT Tietjen, JL Baylon, D Kerr, Z Gong, JM Henderson, CTR Heffern, ...
Biophysical journal 113 (7), 1505-1519, 2017
172017
Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence
K Gavrilov, YE Seo, GT Tietjen, J Cui, CJ Cheng, WM Saltzman
Proceedings of the National Academy of Sciences 112 (48), E6597-E6605, 2015
162015
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