| A living biobank of breast cancer organoids captures disease heterogeneity N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ... Cell 172 (1), 373-386. e10, 2018 | 1468 | 2018 |
| Long-term culture of genome-stable bipotent stem cells from adult human liver M Huch, H Gehart, R Van Boxtel, K Hamer, F Blokzijl, MMA Verstegen, ... Cell 160 (1), 299-312, 2015 | 1441 | 2015 |
| Tissue-specific mutation accumulation in human adult stem cells during life F Blokzijl, J De Ligt, M Jager, V Sasselli, S Roerink, N Sasaki, M Huch, ... Nature 538 (7624), 260-264, 2016 | 880 | 2016 |
| MutationalPatterns: comprehensive genome-wide analysis of mutational processes F Blokzijl, R Janssen, R Van Boxtel, E Cuppen Genome medicine 10, 1-11, 2018 | 555 | 2018 |
| Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer J Drost, R Van Boxtel, F Blokzijl, T Mizutani, N Sasaki, V Sasselli, J de Ligt, ... Science 358 (6360), 234-238, 2017 | 415 | 2017 |
| Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia E Waanders, Z Gu, SM Dobson, Ž Antić, JC Crawford, X Ma, ... Blood cancer discovery 1 (1), 96-111, 2020 | 119 | 2020 |
| Genomic landscape of rat strain and substrain variation R Hermsen, J de Ligt, W Spee, F Blokzijl, S Schäfer, E Adami, S Boymans, ... BMC genomics 16, 1-14, 2015 | 93 | 2015 |
| Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer M Jager, F Blokzijl, E Kuijk, J Bertl, M Vougioukalaki, R Janssen, ... Genome research 29 (7), 1067-1077, 2019 | 79 | 2019 |
| Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure EW Kuijk, S Rasmussen, F Blokzijl, M Huch, H Gehart, P Toonen, ... Scientific reports 6 (1), 22154, 2016 | 61 | 2016 |
| Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures M Jager, F Blokzijl, V Sasselli, S Boymans, R Janssen, N Besselink, ... Nature protocols 13 (1), 59-78, 2018 | 60 | 2018 |
| Mutational processes in hepatocellular carcinoma: the story of aristolochic acid JC Nault, E Letouzé Seminars in liver disease 39 (03), 334-340, 2019 | 30 | 2019 |
| Early divergence of mutational processes in human fetal tissues E Kuijk, F Blokzijl, M Jager, N Besselink, S Boymans, ... Science advances 5 (5), eaaw1271, 2019 | 29 | 2019 |
| Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney F Schutgens, MB Rookmaaker, F Blokzijl, R van Boxtel, R Vries, ... Proceedings of the National Academy of Sciences 114 (52), E11190-E11198, 2017 | 28 | 2017 |
| Chuva de Sousa Lopes SM EW Kuijk, F Blokzijl, M Jager, N Besselink, S Boymans Early divergence of mutational processes in human fetal tissues. Sci Adv 5 (5), 2019 | 9 | 2019 |
| Deficiency of global genome nucleotide excision repair explains mutational signature observed in cancer M Jager, F Blokzijl, E Kuijk, M Vougioukalaki, R Janssen, N Besselink, ... bioRxiv, 221168, 2017 | 1 | 2017 |
| VIBE: An R-package for advanced RNA-seq data exploration, disease stratification and therapeutic targeting I Khatri, SD Asten, LF Moreno, BW Higgs, C Klijn, F Blokzijl, ICRM Kolder bioRxiv, 2023.10. 04.560641, 2023 | | 2023 |
| Decoding the mutational history of human stem cells: From patterns to mechanisms F Blokzijl Utrecht University, 2018 | | 2018 |
| Introduction to MutationalPatterns F Blokzijl, R Janssen, R Van Boxtel, E Cuppen | | 2018 |
| Higher mutation accumulation rate in human stem cells during fetal development than postnatal life F Blokzijl, E Kuijk, M Jager, SMC de Sousa Lopes, R van Boxtel, ... Decoding the mutational history of human stem cells, 117, 2018 | | 2018 |
