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Karl Heilbron
Karl Heilbron
23andMe
Dirección de correo verificada de zoo.ox.ac.uk
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Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ...
The Lancet Neurology 18 (12), 1091-1102, 2019
15292019
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
DP Wightman, IE Jansen, JE Savage, AA Shadrin, S Bahrami, D Holland, ...
Nature genetics 53 (9), 1276-1282, 2021
5042021
Parkinson's disease age at onset genome‐wide association study: defining heritability, genetic loci, and α‐synuclein mechanisms
C Blauwendraat, K Heilbron, CL Vallerga, S Bandres‐Ciga, R Von Coelln, ...
Movement Disorders 34 (6), 866-875, 2019
2882019
A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity
DJ Marchant, CL Bellac, TJ Moraes, SJ Wadsworth, A Dufour, GS Butler, ...
Nature medicine 20 (5), 493-502, 2014
2582014
Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses
B Brumpton, E Sanderson, K Heilbron, FP Hartwig, S Harrison, GÅ Vie, ...
Nature communications 11 (1), 1-13, 2020
2412020
Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia
C Blauwendraat, X Reed, L Krohn, K Heilbron, S Bandres-Ciga, M Tan, ...
Brain 143 (1), 234-248, 2020
1782020
Positive epistasis between co-infecting plasmids promotes plasmid survival in bacterial populations
A San Millan, K Heilbron, RC MacLean
The ISME journal 8 (3), 601-612, 2014
1762014
Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders
C Eijsbouts, T Zheng, NA Kennedy, F Bonfiglio, CA Anderson, ...
Nature genetics 53 (11), 1543-1552, 2021
1292021
The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study
O Giannakopoulou, K Lin, X Meng, MH Su, PH Kuo, RE Peterson, ...
JAMA psychiatry 78 (11), 1258-1269, 2021
1022021
System Genomics of Parkinson’s Disease Consortium; International Parkinson’s Disease Genomics Consortium. Identification of novel risk loci, causal insights, and heritable risk …
MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ...
Lancet Neurol 18 (12), 1091-1102, 2019
942019
Parkinson’s disease determinants, prediction and gene–environment interactions in the UK Biobank
BM Jacobs, D Belete, J Bestwick, C Blauwendraat, S Bandres-Ciga, ...
Journal of Neurology, Neurosurgery & Psychiatry 91 (10), 1046-1054, 2020
692020
Fitness is strongly influenced by rare mutations of large effect in a microbial mutation accumulation experiment
K Heilbron, M Toll-Riera, M Kojadinovic, RC MacLean
Genetics 197 (3), 981-990, 2014
692014
The Parkinson's disease Mendelian randomization research portal
AJ Noyce, S Bandres‐Ciga, J Kim, K Heilbron, D Kia, G Hemani, A Xue, ...
Movement Disorders 34 (12), 1864-1872, 2019
582019
Characterizing the genetic architecture of Parkinson's disease in Latinos
DP Loesch, ARVR Horimoto, K Heilbron, EI Sarihan, M Inca‐Martinez, ...
Annals of neurology 90 (3), 353-365, 2021
552021
Fine‐Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies
L Krohn, RYJ Wu, K Heilbron, JA Ruskey, SB Laurent, C Blauwendraat, ...
Annals of neurology 87 (4), 584-598, 2020
432020
The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa
Q Qi, M Toll-Riera, K Heilbron, GM Preston, RC MacLean
Proceedings of the Royal Society B: Biological Sciences 283 (1822), 20152452, 2016
412016
Discriminating Selection on Lateral Plate Phenotype and Its Underlying Gene, Ectodysplasin, in Threespine Stickleback
DJ Rennison, K Heilbron, RDH Barrett, D Schluter
The American Naturalist 185 (1), 150-156, 2015
352015
The Parkinson’s phenome—traits associated with Parkinson’s disease in a broadly phenotyped cohort
K Heilbron, AJ Noyce, P Fontanillas, B Alipanahi, MA Nalls, P Cannon
NPJ Parkinson's disease 5 (1), 4, 2019
342019
Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects
L Krohn, K Heilbron, C Blauwendraat, RH Reynolds, E Yu, K Senkevich, ...
Nature communications 13 (1), 7496, 2022
282022
Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study
M Rizig, S Bandres-Ciga, MB Makarious, OO Ojo, PW Crea, OV Abiodun, ...
The Lancet Neurology 22 (11), 1015-1025, 2023
232023
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