| UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells JH Kim, A Sharma, SS Dhar, SH Lee, B Gu, CH Chan, HK Lin, MG Lee Cancer research 74 (6), 1705-1717, 2014 | 242 | 2014 |
| Depletion of BRCA1 impairs differentiation but enhances proliferation of mammary epithelial cells S Furuta, X Jiang, B Gu, E Cheng, PL Chen, WH Lee Proceedings of the National Academy of Sciences 102 (26), 9176-9181, 2005 | 184 | 2005 |
| Inactivation of CtIP Leads to Early Embryonic Lethality Mediated by G1 Restraint and to Tumorigenesis by Haploid Insufficiency PL Chen, F Liu, S Cai, X Lin, A Li, Y Chen, B Gu, EYHP Lee, WH Lee Molecular and cellular biology 25 (9), 3535-3542, 2005 | 160 | 2005 |
| KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer H Alam, M Tang, M Maitituoheti, SS Dhar, M Kumar, CY Han, CR Ambati, ... Cancer cell 37 (4), 599-617. e7, 2020 | 151 | 2020 |
| Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation B Gu, P Sun, Y Yuan, RC Moraes, A Li, A Teng, A Agrawal, C Rhéaume, ... Journal of cell biology 185 (5), 811-826, 2009 | 145 | 2009 |
| MLL4 is required to maintain broad H3K4me3 peaks and super-enhancers at tumor suppressor genes SS Dhar, D Zhao, T Lin, B Gu, K Pal, SJ Wu, H Alam, J Lv, K Yun, ... Molecular cell 70 (5), 825-841. e6, 2018 | 127 | 2018 |
| Histone H3 lysine 4 methyltransferases and demethylases in self-renewal anddifferentiation of stem cells B Gu, MG Lee Cell & bioscience 3, 1-14, 2013 | 118 | 2013 |
| Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature S Furuta, JM Wang, S Wei, YM Jeng, X Jiang, B Gu, PL Chen, YHPL Eva, ... Cancer cell 10 (1), 13-24, 2006 | 116 | 2006 |
| Histone methylation modifiers in cellular signaling pathways H Alam, B Gu, MG Lee Cellular and molecular life sciences 72, 4577-4592, 2015 | 111 | 2015 |
| Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells B Gu, K Watanabe, P Sun, M Fallahi, X Dai Cell stem cell 13 (1), 48-61, 2013 | 99 | 2013 |
| BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1 S Zhu, D Zhao, L Yan, W Jiang, JS Kim, B Gu, Q Liu, R Wang, B Xia, ... Nature communications 9 (1), 500, 2018 | 85 | 2018 |
| Pygopus and the Wnt signaling pathway: a diverse set of connections S Jessen, B Gu, X Dai Bioessays 30 (5), 448-456, 2008 | 81 | 2008 |
| A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness SH Lee, TY Chen, SS Dhar, B Gu, K Chen, YZ Kim, W Li, MG Lee Nucleic acids research 44 (22), 10603-10618, 2016 | 74 | 2016 |
| Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells B Gu, K Watanabe, X Dai Cell cycle 11 (1), 79-87, 2012 | 41 | 2012 |
| Expression of PCNA-binding domain of CtIP, a motif required for CtIP localization at DNA replication foci, causes DNA damage and activation of DNA damage checkpoint B Gu, PL Chen Cell Cycle 8 (9), 1409-1420, 2009 | 37 | 2009 |
| Epithelial stem cells: An epigenetic and wnt‐centric perspective B Gu, K Watanabe, X Dai Journal of cellular biochemistry 110 (6), 1279-1287, 2010 | 35 | 2010 |
| Akt phosphorylates Wnt coactivator and chromatin effector Pygo2 at serine 48 to antagonize its ubiquitin/proteasome-mediated degradation Q Li, Y Li, B Gu, L Fang, P Zhou, S Bao, L Huang, X Dai Journal of Biological Chemistry 290 (35), 21553-21567, 2015 | 14 | 2015 |
| Establishment of a scalable manufacturing platform for in-silico-derived ancestral adeno-associated virus vectors B Gu, V Bhat, W Dong, H Pham, S Pubill, N Kasaraneni, E Onishi, F Vitelli, ... Cell Gene Therapy Insights, 2018 | 10 | 2018 |
