Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ... Nature genetics 46 (2), 136-143, 2014 | 567 | 2014 |
Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis MN Weedon, I Cebola, AM Patch, SE Flanagan, E De Franco, R Caswell, ... Nature genetics 46 (1), 61-64, 2014 | 305 | 2014 |
TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors I Cebola, SA Rodríguez-Seguí, CHH Cho, J Bessa, M Rovira, M Luengo, ... Nature cell biology 17 (5), 615-626, 2015 | 233 | 2015 |
Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes I Miguel-Escalada, S Bonàs-Guarch, I Cebola, J Ponsa-Cobas, ... Nature genetics 51 (7), 1137-1148, 2019 | 231 | 2019 |
Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis CJ Rhodes, K Batai, M Bleda, M Haimel, L Southgate, M Germain, ... The lancet respiratory medicine 7 (3), 227-238, 2019 | 144 | 2019 |
Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells A Silva, A Girio, I Cebola, CI Santos, F Antunes, JT Barata Leukemia 25 (6), 960-967, 2011 | 129 | 2011 |
Epigenetic deregulation of the COX pathway in cancer I Cebola, MA Peinado Progress in lipid research 51 (4), 301-313, 2012 | 58 | 2012 |
Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer I Cebola, J Custodio, M Muñoz, A Díez-Villanueva, L Paré, P Prieto, ... Clinical epigenetics 7, 1-11, 2015 | 45 | 2015 |
MiR-184 expression is regulated by AMPK in pancreatic islets A Martinez-Sanchez, MS Nguyen-Tu, I Cebola, A Yavari, P Marchetti, ... The FASEB Journal 32 (5), 2587, 2018 | 44 | 2018 |
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits MC Costanzo, M von Grotthuss, J Massung, D Jang, L Caulkins, ... Cell metabolism 35 (4), 695-710. e6, 2023 | 37 | 2023 |
Epigenetics of hepatic insulin resistance H Maude, C Sanchez-Cabanillas, I Cebola Frontiers in Endocrinology 12, 681356, 2021 | 26 | 2021 |
Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease AM Jobbins, N Haberman, N Artigas, C Amourda, HAB Paterson, S Yu, ... Nucleic Acids Research 50 (6), 3379-3393, 2022 | 17 | 2022 |
Non-coding genome functions in diabetes I Cebola, L Pasquali Journal of molecular endocrinology 56 (1), R1-R20, 2016 | 17 | 2016 |
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice HAB Paterson, S Yu, N Artigas, MA Prado, N Haberman, YF Wang, ... Nature Metabolism 4 (12), 1812-1829, 2022 | 13 | 2022 |
GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements PH Dixon, AP Levine, I Cebola, MMY Chan, AS Amin, A Aich, M Mozere, ... Nature communications 13 (1), 4840, 2022 | 12 | 2022 |
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion M Hu, I Cebola, G Carrat, S Jiang, S Nawaz, A Khamis, M Canouil, ... Cell reports 34 (5), 2021 | 12 | 2021 |
Pancreatic islet transcriptional enhancers and diabetes I Cebola Current diabetes reports 19, 1-12, 2019 | 11 | 2019 |
SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension R Walters, E Vasilaki, J Aman, CN Chen, Y Wu, OD Liang, A Ashek, ... Circulation 147 (21), 1606-1621, 2023 | 9 | 2023 |
One-step dual CRISPR/Cas9 guide RNA cloning protocol A Beucher, I Cebola | 7 | 2019 |
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes L McAllan, D Baranasic, S Villicaña, S Brown, W Zhang, B Lehne, ... Nature Communications 14 (1), 2784, 2023 | 5 | 2023 |