María del Mar Noblejas López
María del Mar Noblejas López
Centro Regional de Investigaciones Biomédicas (UCLM)
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Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer
MM Noblejas-López, C Nieto-Jimenez, M Burgos, M Gómez-Juárez, ...
Journal of Experimental & Clinical Cancer Research 38, 1-9, 2019
Controlled delivery of BET-PROTACs: in vitro evaluation of MZ1-loaded polymeric antibody conjugated nanoparticles in breast cancer
FJ Cimas, E Niza, A Juan, MM Noblejas-López, I Bravo, A Lara-Sanchez, ...
Pharmaceutics 12 (10), 986, 2020
Expression of MHC class I, HLA-A and HLA-B identifies immune-activated breast tumors with favorable outcome
MDM Noblejas-López, C Nieto-Jiménez, S Morcillo Garcia, J Pérez-Peña, ...
Oncoimmunology 8 (10), e1629780, 2019
Trastuzumab-targeted biodegradable nanoparticles for enhanced delivery of dasatinib in HER2+ metastasic breast cancer
E Niza, MM Noblejas-López, I Bravo, C Nieto-Jiménez, JA Castro-Osma, ...
Nanomaterials 9 (12), 1793, 2019
Poly (cyclohexene phthalate) nanoparticles for controlled dasatinib delivery in breast cancer therapy
E Niza, C Nieto-Jiménez, MM Noblejas-López, I Bravo, JA Castro-Osma, ...
Nanomaterials 9 (9), 1208, 2019
Evaluation of transcriptionally regulated genes identifies NCOR1 in hormone receptor negative breast tumors and lung adenocarcinomas as a potential tumor suppressor gene
MM Noblejas-López, S Morcillo-Garcia, C Nieto-Jiménez, ...
PloS one 13 (11), e0207776, 2018
Options to improve the action of PROTACs in cancer: development of controlled delivery nanoparticles
A Juan, MM Noblejas-López, M Arenas-Moreira, C Alonso-Moreno, ...
Frontiers in Cell and Developmental Biology, 3912, 2021
Inhibition of the mitotic kinase PLK1 overcomes therapeutic resistance to BET inhibitors in triple negative breast cancer
C Nieto-Jimenez, EM Galan-Moya, V Corrales-Sanchez, ...
Cancer Letters 491, 50-59, 2020
Genetic mutational status of genes regulating epigenetics: Role of the histone methyltransferase KMT2D in triple negative breast tumors
S Morcillo-Garcia, MM Noblejas-Lopez, C Nieto-Jimenez, J Perez-Peña, ...
PLoS One 14 (4), e0209134, 2019
Mapping of genomic vulnerabilities in the post-translational ubiquitination, SUMOylation and neddylation machinery in breast cancer
J Fuentes-Antrás, AL Alcaraz-Sanabria, EC Morafraile, ...
Cancers 13 (4), 833, 2021
Pharmacological screening and transcriptomic functional analyses identify a synergistic interaction between dasatinib and olaparib in triple‐negative breast cancer
V Corrales‐Sánchez, MM Noblejas‐López, C Nieto‐Jiménez, ...
Journal of Cellular and Molecular Medicine 24 (5), 3117-3127, 2020
MZ1 co-operates with trastuzumab in HER2 positive breast cancer
MM Noblejas-López, C Nieto-Jiménez, EM Galán-Moya, D Tebar-García, ...
Journal of Experimental & Clinical Cancer Research 40, 1-12, 2021
Antitumoral activity of a CDK9 PROTAC compound in HER2-positive breast cancer
MM Noblejas-López, L Gandullo-Sánchez, EM Galán-Moya, ...
International Journal of Molecular Sciences 23 (10), 5476, 2022
Genomic Mapping of Splicing-Related Genes Identify Amplifications in LSM1, CLNS1A, and ILF2 in Luminal Breast Cancer
MM Noblejas-López, I López-Cade, J Fuentes-Antrás, ...
Cancers 13 (16), 4118, 2021
Enhanced antitumoral activity of encapsulated BET inhibitors when combined with PARP inhibitors for the treatment of triple-negative breast and ovarian cancers
A Juan, MM Noblejas-López, I Bravo, M Arenas-Moreira, ...
Cancers 14 (18), 4474, 2022
Transcriptomic profiles of CD47 in breast tumors predict outcome and are associated with immune activation
MM Noblejas-López, M Baliu-Piqué, C Nieto-Jiménez, FJ Cimas, ...
International Journal of Molecular Sciences 22 (8), 3836, 2021
TACkling Cancer by Targeting Selective Protein Degradation
MM Noblejas-López, D Tébar-García, R López-Rosa, A Alcaraz-Sanabria, ...
Pharmaceutics 15 (10), 2442, 2023
T-reg transcriptomic signatures identify response to check-point inhibitors
MM Noblejas-López, E García-Gil, P Pérez-Segura, A Pandiella, B Győrffy, ...
Scientific Reports 14 (1), 10396, 2024
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