| Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy C Delettre, G Lenaers, JM Griffoin, N Gigarel, C Lorenzo, P Belenguer, ... Nature genetics 26 (2), 207-210, 2000 | 1691 | 2000 |
| Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis A Olichon, L Baricault, N Gas, E Guillou, A Valette, P Belenguer, ... Journal of Biological Chemistry 278 (10), 7743-7746, 2003 | 1368 | 2003 |
| OPA1 mutations induce mitochondrial DNA instability and optic atrophy ‘plus’ phenotypes P Amati-Bonneau, ML Valentino, P Reynier, ME Gallardo, B Bornstein, ... Brain 131 (2), 338-351, 2008 | 562 | 2008 |
| The human dynamin‐related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter‐membrane space A Olichon, LJ Emorine, E Descoins, L Pelloquin, L Brichese, N Gas, ... FEBS letters 523 (1-3), 171-176, 2002 | 529 | 2002 |
| Mutation spectrum and splicing variants in the OPA1 gene C Delettre, JM Griffoin, J Kaplan, H Dollfus, B Lorenz, L Faivre, G Lenaers, ... Human genetics 109, 584-591, 2001 | 451 | 2001 |
| Multi-system neurological disease is common in patients with OPA1 mutations P Yu-Wai-Man, PG Griffiths, GS Gorman, CM Lourenco, AF Wright, ... Brain 133 (3), 771-786, 2010 | 438 | 2010 |
| p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. JB Millar, CH McGowan, G Lenaers, R Jones, P Russell The EMBO journal 10 (13), 4301-4309, 1991 | 426 | 1991 |
| Dominant optic atrophy G Lenaers, C Hamel, C Delettre, P Amati-Bonneau, V Procaccio, ... Orphanet journal of rare diseases 7, 1-12, 2012 | 277 | 2012 |
| Mitochondrial dynamics and disease, OPA1 A Olichon, E Guillou, C Delettre, T Landes, L Arnauné-Pelloquin, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1763 (5-6), 500-509, 2006 | 272 | 2006 |
| OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution G Elachouri, S Vidoni, C Zanna, A Pattyn, H Boukhaddaoui, K Gaget, ... Genome research 21 (1), 12-20, 2011 | 256 | 2011 |
| OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosis A Olichon, G Elachouri, L Baricault, C Delettre, P Belenguer, G Lenaers Cell Death & Differentiation 14 (4), 682-692, 2007 | 253 | 2007 |
| TRPV4 channels mediate the infrared laser-evoked response in sensory neurons ES Albert, JM Bec, G Desmadryl, K Chekroud, C Travo, S Gaboyard, ... Journal of neurophysiology 107 (12), 3227-3234, 2012 | 251 | 2012 |
| OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease C Delettre, G Lenaers, L Pelloquin, P Belenguer, CP Hamel Molecular genetics and metabolism 75 (2), 97-107, 2002 | 239 | 2002 |
| OPA1 R445H mutation in optic atrophy associated with sensorineural deafness P Amati‐Bonneau, A Guichet, A Olichon, A Chevrollier, F Viala, S Miot, ... Annals of Neurology: Official Journal of the American Neurological …, 2005 | 197 | 2005 |
| OPA1 isoforms in the hierarchical organization of mitochondrial functions V Del Dotto, P Mishra, S Vidoni, M Fogazza, A Maresca, L Caporali, ... Cell reports 19 (12), 2557-2571, 2017 | 194 | 2017 |
| Mitochondrial fusion is frequent in skeletal muscle and supports excitation–contraction coupling V Eisner, G Lenaers, G Hajnóczky Journal of Cell Biology 205 (2), 179-195, 2014 | 187 | 2014 |
| Effects of OPA1 mutations on mitochondrial morphology and apoptosis: relevance to ADOA pathogenesis A Olichon, T Landes, L Arnauné‐Pelloquin, LJ Emorine, V Mils, A Guichet, ... Journal of cellular physiology 211 (2), 423-430, 2007 | 180 | 2007 |
| OPA1-associated disorders: phenotypes and pathophysiology P Amati-Bonneau, D Milea, D Bonneau, A Chevrollier, M Ferré, V Guillet, ... The international journal of biochemistry & cell biology 41 (10), 1855-1865, 2009 | 174 | 2009 |
| OPA3 gene mutations responsible for autosomal dominant optic atrophy and cataract P Reynier, P Amati-Bonneau, C Verny, A Olichon, G Simard, A Guichet, ... Journal of Medical Genetics 41 (9), e110-e110, 2004 | 173 | 2004 |
| Exploring the pharmacological properties of insect nicotinic acetylcholine receptors SH Thany, G Lenaers, V Raymond-Delpech, DB Sattelle, B Lapied Trends in pharmacological sciences 28 (1), 14-22, 2007 | 166 | 2007 |
