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Ondrej Havranek
Ondrej Havranek
Group Leader, BIOCEV, First Faculty of Medicine, Charles University, Prague, Czech Republic
Dirección de correo verificada de lf1.cuni.cz - Página principal
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Tonic B-cell receptor signaling in diffuse large B-cell lymphoma
O Havranek, J Xu, S Köhrer, Z Wang, L Becker, JM Comer, J Henderson, ...
Blood, The Journal of the American Society of Hematology 130 (8), 995-1006, 2017
1032017
Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer
P Kleiblova, L Stolarova, K Krizova, F Lhota, J Hojny, P Zemankova, ...
International journal of cancer 145 (7), 1782-1797, 2019
842019
Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition
S Köhrer, O Havranek, F Seyfried, C Hurtz, GP Coffey, E Kim, ...
Leukemia 30 (6), 1246-1254, 2016
792016
Cotargeting of BCL2 with Venetoclax and MCL1 with S63845 Is Synthetically Lethal In Vivo in Relapsed Mantle Cell Lymphoma
D Prukova, L Andera, Z Nahacka, J Karolova, M Svaton, M Klanova, ...
Clinical Cancer Research 25 (14), 4455-4465, 2019
722019
Inhibition of demethylase KDM6B sensitizes diffuse large B-cell lymphoma to chemotherapeutic drugs
R Mathur, L Sehgal, O Havranek, S Köhrer, T Khashab, N Jain, JA Burger, ...
Haematologica 102 (2), 373, 2017
592017
B-cell receptor signaling regulates metabolism in chronic lymphocytic leukemia
HV Vangapandu, O Havranek, ML Ayres, BA Kaipparettu, K Balakrishnan, ...
Molecular Cancer Research 15 (12), 1692-1703, 2017
552017
Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma
N Jain, K Hartert, S Tadros, W Fiskus, O Havranek, MCJ Ma, A Bouska, ...
Science translational medicine 11 (497), eaav5599, 2019
542019
The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population
Z Kleibl, O Havranek, I Hlavata, J Novotny, J Sevcik, P Pohlreich, ...
European journal of cancer 45 (4), 618-624, 2009
502009
Association of germline CHEK2 gene variants with risk and prognosis of non-Hodgkin lymphoma
O Havranek, P Kleiblova, J Hojny, F Lhota, P Soucek, M Trneny, Z Kleibl
PLoS One 10 (10), e0140819, 2015
422015
Analysis of CHEK2 FHA domain in Czech patients with sporadic breast cancer revealed distinct rare genetic alterations
Z Kleibl, O Havranek, J Novotny, P Kleiblova, P Soucek, P Pohlreich
Breast cancer research and treatment 112, 159-164, 2008
382008
Overexpression of CD200 is a stem cell-specific mechanism of immune evasion in AML
S Herbrich, N Baran, T Cai, C Weng, MJL Aitken, SM Post, J Henderson, ...
Journal for immunotherapy of cancer 9 (7), 2021
282021
Targeting phosphatidylinositol 3 kinase-β and-δ for Bruton tyrosine kinase resistance in diffuse large B-cell lymphoma
N Jain, S Singh, G Laliotis, A Hart, E Muhowski, K Kupcova, T Chrbolkova, ...
Blood Advances 4 (18), 4382-4392, 2020
242020
Inhibition of PIM kinases in DLBCL targets MYC transcriptional program and augments the efficacy of anti-CD20 antibodies
M Szydłowski, F Garbicz, E Jabłońska, P Górniak, D Komar, B Pyrzyńska, ...
Cancer Research 81 (23), 6029-6043, 2021
232021
CHEK2 gene alterations in the forkhead-associated domain, 1100delC and del5395 do not modify the risk of sporadic pancreatic cancer
B Mohelnikova-Duchonova, O Havranek, I Hlavata, L Foretova, Z Kleibl, ...
Cancer epidemiology 34 (5), 656-658, 2010
182010
Alterations of CHEK2 forkhead-associated domain increase the risk of Hodgkin lymphoma
O Havranek, M Spacek, P Hubacek, H Mocikova, J Markova, M Trneny, ...
Neoplasma 58 (5), 392, 2011
172011
Anti-apoptotic MCL1 protein represents critical survival molecule for most Burkitt lymphomas and BCL2-negative diffuse large B-cell lymphomas
M Klanova, D Kazantsev, E Pokorna, T Zikmund, J Karolova, M Behounek, ...
Molecular Cancer Therapeutics 21 (1), 89-99, 2022
122022
Rapid detection of CAA/CAG repeat polymorphism in the AIB1 gene using DHPLC
Z Kleibl, O Havranek, J Prokopcova
Journal of biochemical and biophysical methods 70 (3), 511-513, 2007
102007
Detecting Förster resonance energy transfer in living cells by conventional and spectral flow cytometry
J Henderson, O Havranek, MCJ Ma, V Herman, K Kupcova, T Chrbolkova, ...
Cytometry Part A 101 (10), 818-834, 2022
82022
No association between the TP53 codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma
O Havranek, M Spacek, P Hubacek, H Mocikova, K Benesova, P Soucek, ...
Leukemia research 35 (8), 1117-1119, 2011
82011
Assessing regulated cell death modalities as an efficient tool for in vitro nanotoxicity screening: a review
A Tkachenko, A Onishchenko, V Myasoedov, S Yefimova, O Havranek
Nanotoxicology 17 (3), 218-248, 2023
72023
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