Jonathan Lei
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Proteogenomics connects somatic mutations to signalling in breast cancer
P Mertins, DR Mani, KV Ruggles, MA Gillette, KR Clauser, P Wang, ...
Nature 534 (7605), 55-62, 2016
Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRα gene in the X chromosome pseudoautosomal region 1
M Martinez-Moczygemba, ML Doan, O Elidemir, LL Fan, SW Cheung, ...
The Journal of experimental medicine 205 (12), 2711-2716, 2008
JAK kinases control IL‐5 receptor ubiquitination, degradation, and internalization
M Martinez‐Moczygemba, DP Huston, JT Lei
Journal of leukocyte biology 81 (4), 1137-1148, 2007
Functional annotation of ESR1 gene fusions in estrogen receptor-positive breast cancer
JT Lei, J Shao, J Zhang, M Iglesia, DW Chan, J Cao, M Anurag, P Singh, ...
Cell reports 24 (6), 1434-1444. e7, 2018
Separate endocytic pathways regulate IL‐5 receptor internalization and signaling
JT Lei, M Martinez‐Moczygemba
Journal of leukocyte biology 84 (2), 499-509, 2008
Loss of MutL disrupts CHK2-dependent cell-cycle control through CDK4/6 to promote intrinsic endocrine therapy resistance in primary breast cancer
S Haricharan, N Punturi, P Singh, KR Holloway, M Anurag, J Schmelz, ...
Cancer discovery 7 (10), 1168-1183, 2017
ESR1 alterations and metastasis in estrogen receptor positive breast cancer
JT Lei, X Gou, S Seker, MJ Ellis
Journal of cancer metastasis and treatment 5, 2019
Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets
LA Gates, G Gu, Y Chen, AD Rohira, JT Lei, RA Hamilton, Y Yu, ...
Oncogene 37 (33), 4581-4598, 2018
DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer
R Matsunuma, DW Chan, BJ Kim, P Singh, A Han, AB Saltzman, C Cheng, ...
Proceedings of the National Academy of Sciences 115 (51), E11978-E11987, 2018
Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling
JT Lei, T Mazumdar, M Martinez-Moczygemba
Journal of Biological Chemistry 286 (46), 40091-40103, 2011
Neurofibromin is an estrogen receptor-α transcriptional co-repressor in breast cancer
ZY Zheng, M Anurag, JT Lei, J Cao, P Singh, J Peng, H Kennedy, ...
Cancer Cell 37 (3), 387-402. e7, 2020
ESR1 fusions drive endocrine therapy resistance and metastasis in breast cancer
JT Lei, X Gou, MJ Ellis
Molecular & cellular oncology 5 (6), e1526005, 2018
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
C Huang, L Chen, SR Savage, RV Eguez, Y Dou, Y Li, ...
Cancer cell 39 (3), 361-379. e16, 2021
Proteogenomic landscape of breast cancer tumorigenesis and targeted therapy
K Krug, EJ Jaehnig, S Satpathy, L Blumenberg, A Karpova, M Anurag, ...
Cell 183 (5), 1436-1456. e31, 2020
Endocrine therapy resistance: new insights
JT Lei, M Anurag, S Haricharan, X Gou, MJ Ellis
The Breast 48, S26-S30, 2019
Mammary ductal environment is necessary for faithful maintenance of estrogen signaling in ER+ breast cancer
S Haricharan, J Lei, M Ellis
Cancer Cell 29 (3), 249-250, 2016
Copy number alterations associated with clinical features in an underrepresented population with breast cancer
RM Rodrigues‐Peres, B de S Carvalho, M Anurag, JT Lei, L Conz, ...
Molecular genetics & genomic medicine 7 (7), e00750, 2019
Proteogenomic and metabolomic characterization of human glioblastoma
LB Wang, A Karpova, MA Gritsenko, JE Kyle, S Cao, Y Li, D Rykunov, ...
Cancer cell 39 (4), 509-528. e20, 2021
Abstract PD8-03: ESR1 gene fusions drive endocrine therapy resistance and metastasis in breast cancer
JT Lei, J Shao, J Zhang, M Iglesia, DW Chan, J Cao, M Anurag, P Singh, ...
Cancer Research 78 (4 Supplement), PD8-03-PD8-03, 2018
NF1 as an estrogen receptor-α co-repressor in breast cancer
EC Chang, M Anurag, J Gao, B Cakar, X Du, J Li, P Lavere, JT Lei, ...
Cancer Research 78 (13 Supplement), 1814-1814, 2018
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