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George Poulogiannis
George Poulogiannis
Dirección de correo verificada de icr.ac.uk
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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
D Anastasiou, G Poulogiannis, JM Asara, MB Boxer, J Jiang, M Shen, ...
Science 334 (6060), 1278-1283, 2011
12172011
Reprogramming of fatty acid metabolism in cancer
N Koundouros, G Poulogiannis
British journal of cancer 122 (1), 4-22, 2020
9832020
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling
Y Yu, SO Yoon, G Poulogiannis, Q Yang, XM Ma, J Villén, N Kubica, ...
Science 332 (6035), 1322-1326, 2011
9702011
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4
A Csibi, SM Fendt, C Li, G Poulogiannis, AY Choo, DJ Chapski, SM Jeong, ...
Cell 153 (4), 840-854, 2013
6622013
Asparagine bioavailability governs metastasis in a model of breast cancer
SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ...
Nature 554 (7692), 378-381, 2018
4492018
Perioperative events influence cancer recurrence risk after surgery
JG Hiller, NJ Perry, G Poulogiannis, B Riedel, EK Sloan
Nature reviews Clinical oncology 15 (4), 205-218, 2018
4092018
Oncogenic KRAS regulates tumor cell signaling via stromal reciprocation
CJ Tape, S Ling, M Dimitriadi, KM McMahon, JD Worboys, HS Leong, ...
Cell 165 (4), 910-920, 2016
4082016
Phosphoinositide 3-kinase/Akt signaling and redox metabolism in cancer
N Koundouros, G Poulogiannis
Frontiers in oncology 8, 160, 2018
3402018
DNA mismatch repair deficiency in sporadic colorectal cancer and Lynch syndrome
G Poulogiannis, IM Frayling, MJ Arends
Histopathology 56 (2), 167-179, 2010
3022010
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
G Poulogiannis, RE McIntyre, M Dimitriadi, JR Apps, CH Wilson, ...
Proceedings of the National Academy of Sciences 107 (34), 15145-15150, 2010
2422010
DNA damage, repair, and cancer metabolism
MO Turgeon, NJS Perry, G Poulogiannis
Frontiers in oncology 8, 15, 2018
2312018
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex
SG Kim, GR Hoffman, G Poulogiannis, GR Buel, YJ Jang, KW Lee, ...
Molecular cell 49 (1), 172-185, 2013
2302013
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors
BM Emerling, JB Hurov, G Poulogiannis, KS Tsukazawa, R Choo-Wing, ...
Cell 155 (4), 844-857, 2013
1822013
Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance
LA Martin, R Ribas, N Simigdala, E Schuster, S Pancholi, T Tenev, ...
Nature communications 8 (1), 1865, 2017
1372017
PARK2 depletion connects energy and oxidative stress to PI3K/Akt activation via PTEN S-nitrosylation
A Gupta, S Anjomani-Virmouni, N Koundouros, M Dimitriadi, ...
Molecular cell 65 (6), 999-1013. e7, 2017
1262017
Metabolic fingerprinting links oncogenic PIK3CA with enhanced arachidonic acid-derived eicosanoids
N Koundouros, E Karali, A Tripp, A Valle, P Inglese, NJS Perry, DJ Magee, ...
Cell 181 (7), 1596-1611. e27, 2020
922020
Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation
A van Weverwijk, N Koundouros, M Iravani, M Ashenden, Q Gao, ...
Nature communications 10 (1), 2698, 2019
922019
A constitutively activated form of the p110β isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice
SH Lee, G Poulogiannis, S Pyne, S Jia, L Zou, S Signoretti, M Loda, ...
Proceedings of the National Academy of Sciences 107 (24), 11002-11007, 2010
822010
Mutated K‐rasAsp12 promotes tumourigenesis in ApcMin mice more in the large than the small intestines, with synergistic effects between K‐ras and Wnt pathways
F Luo, DG Brooks, H Ye, R Hamoudi, G Poulogiannis, CE Patek, ...
International journal of experimental pathology 90 (5), 558-574, 2009
752009
Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients
BM Emerling, CH Benes, G Poulogiannis, EL Bell, K Courtney, H Liu, ...
Proceedings of the National Academy of Sciences 110 (9), 3483-3488, 2013
732013
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Artículos 1–20