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Álvaro Curiel García
Álvaro Curiel García
Postdoctoral Research Fellow, The Herbert Irving Comprehensive Cancer Center - Columbia University
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
Functional Classification of BRCA2 DNA Variants by Splicing Assays in a Large Minigene with 9 Exons.
A Acedo, C Hernández Moro, Á Curiel-García, EA Velasco
Human Mutation, 2014
642014
Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling
B Oldrini, Á Curiel-García, C Marques, V Matia, Ö Uluçkan, ...
Nature communications 9 (1), 1466, 2018
602018
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
B Oldrini, WY Hsieh, H Erdjument-Bromage, P Codega, MS Carro, ...
Nature communications 8 (1), 2035, 2017
252017
Pancreatic ductal adenocarcinoma comprises coexisting regulatory states with both common and distinct dependencies
P Laise, M Turunen, HC Maurer, AG Curiel, E Elyada, B Schmierer, ...
Biorxiv, preprint, 2020
152020
Dianhydrogalactitol overcomes multiple temozolomide resistance mechanisms in glioblastoma
M Jiménez-Alcázar, Á Curiel-García, P Nogales, J Perales-Patón, ...
Molecular cancer therapeutics 20 (6), 1029-1038, 2021
72021
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression
MC Hasselluhn, AR Decker-Farrell, L Vlahos, DH Thomas, ...
Cancer Discovery 14 (2), 348-361, 2024
52024
Generation of orthotopic patient-derived xenograft models for pancreatic cancer using tumor slices
A Curiel-Garcia, AR Decker-Farrell, SA Sastra, KP Olive
STAR protocols 3 (4), 101899, 2022
32022
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma
UN Wasko, J Jiang, A Curiel-Garcia, Y Wang, B Lee, M Orlen, ...
bioRxiv, 2023
22023
Pharmacological targeting of the receptor ALK inhibits tumorigenicity and overcomes chemoresistance in pancreatic ductal adenocarcinoma
B Parejo-Alonso, A Royo-García, P Espiau-Romera, S Courtois, ...
Biomedicine & Pharmacotherapy 158, 114162, 2023
22023
Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer
HC Maurer, A Curiel-Garcia, S Holmstrom, P Laise, CF Palermo, ...
bioRxiv, 2023
12023
Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer
P Laise, M Turunen, AC Garcia, L Tomassoni, HC Maurer, E Elyada, ...
bioRxiv, 2020.10. 27.357269, 2020
12020
DRES-12. FUNCTIONAL GENETIC APPROACHES TO OVERCOME TEMOZOLOMIDE RESISTANCE IN GLIOBLASTOMA
P Nogales-Gomez, J Perales-Patón, A Jimenez-Schuhmacher, ...
Neuro-oncology 20 (Suppl 6), vi78, 2018
12018
Tumor-selective activity of RAS-GTP inhibition in pancreatic cancer
UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ...
Nature, 1-3, 2024
2024
Disrupting local immunosuppression by combined myCAF/myeloid targeting in pancreatic cancer
MC Hasselluhn, D Thomas, L Vlahos, A Curiel-Garcia, AR Decker-Farrell, ...
Cancer Research 84 (6_Supplement), 1596-1596, 2024
2024
Adaptive heterogeneity enables the survival of residual malignant PDAC cells in response to RAS-GTP inhibition
L Tomassoni, UN Wasko, AC Garcia, TC Dalton, P Laise, SA Sastra, ...
Cancer Research 84 (6_Supplement), 3874-3874, 2024
2024
RAS-GTP inhibition modulates Hedgehog signaling, suppressing myCAFs and promoting iCAFs in pancreatic ductal adenocarcinoma
M Hasselluhn, L Tomassoni, U Wasko, A Curiel-Garcia, T Dalton, ...
Cancer Research 84 (6_Supplement), 1578-1578, 2024
2024
RNA-based precision medicine predicts sensitivity to selinexor in select pancreatic ductal adenocarcinoma patients
A Curiel-Garcia, L Tomassoni, TC Dalton, AR Decker-Farrell, CF Palermo, ...
Cancer Research 84 (6_Supplement), 934-934, 2024
2024
Resistance to RAS-GTP inhibition in models of pancreatic ductal adenocarcinoma arises downstream of RAS effectors
UN Wasko, J Jiang, TC Dalton, A Curiel-Garcia, AC Edwards, Y Wang, ...
Cancer Research 84 (6_Supplement), 1927-1927, 2024
2024
BMAL2 is a KRAS-dependent master regulator of hypoxic response in pancreatic ductal adenocarcinoma
AC Garcia, CH Maurer, K Hollinshead, P Laise, A Andren, SA Sastra, ...
Cancer Research 83 (7_Supplement), 4803-4803, 2023
2023
Combination CAF/myeloid targeting in PDAC.
MC Hasselluhn, LJ Vlahos, D Thomas, AC Garcia, AR Decker, TC Dalton, ...
CANCER RESEARCH 82 (22), 131-132, 2022
2022
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