Henk Granzier
Henk Granzier
Professor of Cellular and Molecular Medicine, Physiology, Biomedical Engineering
Verified email at email.arizona.edu
Cited by
Cited by
Folding-unfolding transitions in single titin molecules characterized with laser tweezers
MSZ Kellermayer, SB Smith, HL Granzier, C Bustamante
Science 276 (5315), 1112-1116, 1997
The complete gene sequence of titin, expression of an unusual≈ 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system
ML Bang, T Centner, F Fornoff, AJ Geach, M Gotthardt, M McNabb, ...
Circulation research 89 (11), 1065-1072, 2001
Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments
HL Granzier, TC Irving
Biophysical journal 68 (3), 1027-1044, 1995
The giant protein titin: a major player in myocardial mechanics, signaling, and disease
HL Granzier, S Labeit
Circulation research 94 (3), 284-295, 2004
Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy
B Gerull, M Gramlich, J Atherton, M McNabb, K Trombitás, ...
Nature genetics 30 (2), 201-204, 2002
Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy
SF Nagueh, G Shah, Y Wu, G Torre-Amione, NMP King, S Lahmers, ...
Circulation 110 (2), 155-162, 2004
Differential expression of cardiac titin isoforms and modulation of cellular stiffness
O Cazorla, A Freiburg, M Helmes, T Centner, M McNabb, Y Wu, ...
Circulation research 86 (1), 59-67, 2000
Myocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titin
MR Zile, CF Baicu, J S. Ikonomidis, RE Stroud, PJ Nietert, AD Bradshaw, ...
Circulation 131 (14), 1247-1259, 2015
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain
T Centner, J Yano, E Kimura, AS McElhinny, K Pelin, CC Witt, ML Bang, ...
Journal of molecular biology 306 (4), 717-726, 2001
Muscle assembly: a titanic achievement?
CC Gregorio, H Granzier, H Sorimachi, S Labeit
Current opinion in cell biology 11 (1), 18-25, 1999
Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity
A Freiburg, K Trombitas, W Hell, O Cazorla, F Fougerousse, T Centner, ...
Circulation research 86 (11), 1114-1121, 2000
Calcium-dependent molecular spring elements in the giant protein titin
D Labeit, K Watanabe, C Witt, H Fujita, Y Wu, S Lahmers, T Funck, ...
Proceedings of the National Academy of Sciences 100 (23), 13716-13721, 2003
The NH2 Terminus of Titin Spans the Z-Disc: Its Interaction with a Novel 19-kD Ligand (T-cap) Is Required for Sarcomeric Integrity
CC Gregorio, K Trombitás, T Centner, B Kolmerer, G Stier, K Kunke, ...
The Journal of cell biology 143 (4), 1013-1027, 1998
The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules
MK Miller, ML Bang, CC Witt, D Labeit, C Trombitas, K Watanabe, ...
Journal of molecular biology 333 (5), 951-964, 2003
Protein kinase A phosphorylates titin’s cardiac-specific N2B domain and reduces passive tension in rat cardiac myocytes
R Yamasaki, Y Wu, M McNabb, M Greaser, S Labeit, H Granzier
Circulation research 90 (11), 1181-1188, 2002
Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium
S Lahmers, Y Wu, DR Call, S Labeit, H Granzier
Circulation research 94 (4), 505-513, 2004
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies
ML Bang, RE Mudry, AS McElhinny, K Trombitás, AJ Geach, R Yamasaki, ...
The Journal of cell biology 153 (2), 413-428, 2001
MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination
SH Witt, H Granzier, CC Witt, S Labeit
Journal of molecular biology 350 (4), 713-722, 2005
Right ventricular diastolic impairment in patients with pulmonary arterial hypertension
S Rain, ML Handoko, P Trip, CTJ Gan, N Westerhof, GJ Stienen, ...
Circulation 128 (18), 2016-2025, 2013
Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy–overlap syndromes
M Taylor, S Graw, G Sinagra, C Barnes, D Slavov, F Brun, B Pinamonti, ...
Circulation 124 (8), 876-885, 2011
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