Alvaro Aytes
Alvaro Aytes
Group Leader, Institut d'Investigacions Biomediques de Bellvitge
Verified email at columbia.edu - Homepage
TitleCited byYear
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
S Melo, A Villanueva, C Moutinho, V Davalos, R Spizzo, C Ivan, S Rossi, ...
Proceedings of the National Academy of Sciences 108 (11), 4394-4399, 2011
1742011
Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy
A Aytes, A Mitrofanova, C Lefebvre, MJ Alvarez, M Castillo-Martin, ...
Cancer cell 25 (5), 638-651, 2014
1622014
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer
V Fernandez-Majada, C Aguilera, A Villanueva, F Vilardell, ...
Proceedings of the National Academy of Sciences 104 (1), 276-281, 2007
1352007
A molecular signature predictive of indolent prostate cancer
S Irshad, M Bansal, M Castillo-Martin, T Zheng, A Aytes, S Wenske, ...
Science translational medicine 5 (202), 202ra122-202ra122, 2013
1142013
DNA-PKcs-mediated transcriptional regulation drives prostate cancer progression and metastasis
JF Goodwin, V Kothari, JM Drake, S Zhao, E Dylgjeri, JL Dean, ...
Cancer cell 28 (1), 97-113, 2015
842015
ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer
A Aytes, A Mitrofanova, CW Kinkade, C Lefebvre, M Lei, V Phelan, ...
Proceedings of the National Academy of Sciences 110 (37), E3506-E3515, 2013
812013
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
CA Maxwell, J Benítez, L Gómez-Baldó, A Osorio, N Bonifaci, ...
PLoS biology 9 (11), e1001199, 2011
762011
B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer
J Wang, T Kobayashi, N Floc'h, CW Kinkade, A Aytes, D Dankort, ...
Cancer research 72 (18), 4765-4776, 2012
702012
Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model
N Floc'h, CW Kinkade, T Kobayashi, A Aytes, C Lefebvre, A Mitrofanova, ...
Cancer research 72 (17), 4483-4493, 2012
612012
Stromal interaction molecule 2 (STIM2) is frequently overexpressed in colorectal tumors and confers a tumor cell growth suppressor phenotype
A Aytes, DG Molleví, M Martinez‐Iniesta, M Nadal, A Vidal, A Morales, ...
Molecular carcinogenesis 51 (9), 746-753, 2012
502012
PRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressiveness
DG Mollevi, A Aytes, L Padulles, M Martínez-Iniesta, N Baixeras, ...
British journal of cancer 99 (10), 1718, 2008
452008
Predicting drug response in human prostate cancer from preclinical analysis of in vivo mouse models
A Mitrofanova, A Aytes, M Zou, MM Shen, C Abate-Shen, A Califano
Cell reports 12 (12), 2060-2071, 2015
202015
Cross-species analysis of genome-wide regulatory networks identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy
A Aytes, A Mitrofanova, C Lefebvre, MJ Alvarez, M Castillo-Martin, ...
Cancer Cell 25 (5), 638, 2014
132014
PRL-3 overexpression in epithelial cells is induced by surrounding stromal fibroblasts
DG Molleví, A Aytes, M Berdiel, L Padullés, M Martínez-Iniesta, X Sanjuan, ...
Molecular cancer 8 (1), 46, 2009
102009
Epigenetic regulation in prostate cancer progression
K Ruggero, S Farran-Matas, A Martinez-Tebar, A Aytes
Current molecular biology reports 4 (2), 101-115, 2018
92018
BRCA2 and other DDR genes in prostate cancer
P Nombela, R Lozano, A Aytes, J Mateo, D Olmos, E Castro
Cancers 11 (3), 352, 2019
32019
Orthoxenografts of testicular germ cell tumors demonstrate genomic changes associated with cisplatin resistance and identify PDMP as a resensitizing agent
JM Piulats, A Vidal, FJ García-Rodríguez, C Muñoz, M Nadal, C Moutinho, ...
Clinical Cancer Research 24 (15), 3755-3766, 2018
22018
NSD2 is a conserved driver of metastatic prostate cancer progression
A Aytes, A Giacobbe, A Mitrofanova, K Ruggero, J Cyrta, J Arriaga, ...
Nature communications 9 (1), 5201, 2018
12018
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing (vol 108, pg 4394, 2011)
S Melo, A Villanueva, C Moutinho, V Davalos, R Spizzo, C Ivan, S Rossi, ...
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF …, 2017
12017
Defining a mutational signature for endometrial cancer screening and early detection
L Costas, L Palomero, Y Benavente, M Guardiola, J Frias-Gomez, ...
Cancer epidemiology 61, 129-132, 2019
2019
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