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Valerie Uytterhoeven
Valerie Uytterhoeven
Staff Scientist
Dirección de correo verificada de kuleuven.vib.be
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Loss of skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteins
V Uytterhoeven, S Kuenen, J Kasprowicz, K Miskiewicz, P Verstreken
Cell 145 (1), 117-132, 2011
2282011
Hsc70-4 deforms membranes to promote synaptic protein turnover by endosomal microautophagy
V Uytterhoeven, E Lauwers, I Maes, K Miskiewicz, MN Melo, J Swerts, ...
Neuron 88 (4), 735-748, 2015
1692015
Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration
AC Fernandes, V Uytterhoeven, S Kuenen, YC Wang, JR Slabbaert, ...
Journal of Cell Biology 207 (4), 453-462, 2014
1002014
Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein.
TDR Gomes LA, Hipp SA, Rijal Upadhaya A, Balakrishnan K, Ospitalieri S ...
Acta Neuropathologica, 2019
942019
Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function
B Fischer, K Lüthy, J Paesmans, C De Koninck, I Maes, J Swerts, ...
Nature structural & molecular biology 23 (11), 965-973, 2016
612016
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
P Largo-Barrientos, N Apostolo, E Creemers, Z Callaerts-Vegh, J Swerts, ...
Neuron 109 (5), 767-777. e5, 2021
502021
Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation
LA Gomes, V Uytterhoeven, D Lopez-Sanmartin, SO Tomé, T Tousseyn, ...
Acta Neuropathologica, 1-20, 0
36
Shawn, the Drosophila homolog of SLC25A39/40, is a mitochondrial carrier that promotes neuronal survival
JR Slabbaert, S Kuenen, J Swerts, I Maes, V Uytterhoeven, J Kasprowicz, ...
Journal of Neuroscience 36 (6), 1914-1929, 2016
312016
Mitochondria re-set epilepsy
V Uytterhoeven, N Kaempf, P Verstreken
Neuron 102 (5), 907-910, 2019
92019
Synaptic tau and synaptogyrin‐3 are promising targets to tackle tauopathies
P Largo‐Barrientos, V Uytterhoeven, J de Wit, B De Strooper, ...
Alzheimer's & Dementia 17, e054187, 2021
42021
Tackling Alzheimer’s Disease pathology by modulating the binding of Tau to synaptic vesicles.
P Largo-Barrientos, V Uytterhoeven, P Verstreken
Belgian Brain Congress 2018 — Belgian Brain Council., 2019
22019
Increased endosomal microautophagy reduces Tau driven synaptic dysfunction.
V Uytterhoeven, L Deaulmerie, P Verstreken
Belgian Brain Congress 2018 — Belgian Brain Council., 10.3389/conf.fnins …, 2019
22019
Identification of novel genes involved in synaptic communication
AC Fernandes, J Slabbaert, S Kuenen, J Kasprowicz, V Uytterhoeven, ...
Journal of neurogenetics 24, 42-42, 2010
12010
Combined proteomic and genetic screens identify Crmp as a mediator of Tau-induced synapse degeneration
P Largo-Barrientos, R Praschberger, F Impens, V Uytterhoeven, ...
Alzheimer's Association International Conference, 2023
2023
Lowering Synaptogyrin‐3 Expression Rescues Tau‐Induced Memory Deficits and Synaptic Loss in the Presence of Microglial Activation
P Largo‐Barrientos, B De Strooper, TL Spires‐Jones, J de Wit, ...
Alzheimer's & Dementia 18, e064090, 2022
2022
Tau, synapses and brain disease
P Largo Barrientos
2022
The pathogenic mutation in tau defines the route of tau accumulation at presynapses
V Uytterhoeven, L Deaulmerie, N Schoovaerts, P Verstreken
Alzheimer's & Dementia 17, e053728, 2021
2021
Loss of synaptogyrin‐3 rescues tau‐induced memory defects and synaptic loss in the presence of microglial activation: Developing topics
P Largo‐Barrientos, B de Strooper, T Spires‐Jones, J de Wit, ...
Alzheimer's & Dementia 16, e047527, 2020
2020
Increased HSC70‐4/HSPA8 regulated autophagy reduces tau‐mediated synaptic dysfunction: Molecular and cell biology/tau
V Uytterhoeven, L Deaulmerie, P Verstreken
Alzheimer's & Dementia 16, e037892, 2020
2020
Pathogenic forms of Tau accumulate diversely at presynapses
V Uytterhoeven, L Deaulmerie, N Schoovaerts, P Verstreken
AAIC Neuroscience Next, 2020
2020
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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