| Inhibition of LRRK2 kinase activity stimulates macroautophagy C Manzoni, A Mamais, S Dihanich, R Abeti, MPM Soutar, H Plun-Favreau, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 2900-2910, 2013 | 173 | 2013 |
| Evidence that glycogen synthase kinase‐3 isoforms have distinct substrate preference in the brain MPM Soutar, WY Kim, R Williamson, M Peggie, CJ Hastie, H McLauchlan, ... Journal of neurochemistry 115 (4), 974-983, 2010 | 147 | 2010 |
| Intracellular pH modulates autophagy and mitophagy AV Berezhnov, MPM Soutar, EI Fedotova, MS Frolova, H Plun-Favreau, ... Journal of Biological Chemistry 291 (16), 8701-8708, 2016 | 129 | 2016 |
| mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1 C Manzoni, A Mamais, DA Roosen, S Dihanich, MPM Soutar, ... Scientific reports 6 (1), 35106, 2016 | 92 | 2016 |
| Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation M Delgado-Camprubi, N Esteras, MPM Soutar, H Plun-Favreau, ... Cell Death & Differentiation 24 (1), 120-131, 2017 | 68 | 2017 |
| FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy MPM Soutar, L Kempthorne, E Annuario, C Luft, S Wray, R Ketteler, ... Autophagy 15 (11), 2002-2011, 2019 | 67 | 2019 |
| Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation AR Cole, MPM Soutar, M Rembutsu, L van Aalten, CJ Hastie, ... Journal of Biological Chemistry 283 (26), 18227-18237, 2008 | 66 | 2008 |
| Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour C Beall, DL Hamilton, J Gallagher, L Logie, K Wright, MP Soutar, S Dadak, ... Diabetologia 55, 2432-2444, 2012 | 65 | 2012 |
| Increased CRMP2 phosphorylation is observed in Alzheimer's disease; does this tell us anything about disease development? MPM Soutar, P Thornhill, AR Cole, C Sutherland Current Alzheimer Research 6 (3), 269-278, 2009 | 61 | 2009 |
| AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons MPM Soutar, L Kempthorne, S Miyakawa, E Annuario, D Melandri, ... Scientific reports 8 (1), 8855, 2018 | 60 | 2018 |
| Bi-allelic JAM2 variants lead to early-onset recessive primary familial brain calcification LV Schottlaender, R Abeti, Z Jaunmuktane, C Macmillan, V Chelban, ... The American Journal of Human Genetics 106 (3), 412-421, 2020 | 54 | 2020 |
| Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11. 2 and MAPT H1 loci MPM Soutar, D Melandri, B O’Callaghan, E Annuario, AE Monaghan, ... Brain 145 (12), 4349-4367, 2022 | 28 | 2022 |
| mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition C Manzoni, A Mamais, S Dihanich, MPM Soutar, H Plun-Favreau, ... Bioscience reports 38 (2), BSR20171669, 2018 | 19 | 2018 |
| Novel procedure to investigate the effect of phosphorylation on protein complex formation in vitro and in cells M Rembutsu, MPM Soutar, L Van Aalten, R Gourlay, CJ Hastie, ... Biochemistry 47 (7), 2153-2161, 2008 | 18 | 2008 |
| Oleate induces KATP channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge S Dadak, C Beall, JMV Walker, MPM Soutar, RJ McCrimmon, ... Neuroscience 346, 29-42, 2017 | 12 | 2017 |
| Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at Chr16q11. 2 and on the MAPT H1 allele MPM Soutar, D Melandri, B O’Callaghan, E Annuario, AE Monaghan, ... BioRxiv, 2020.01. 06.896241, 2020 | 11 | 2020 |
| Haploinsufficiency of progranulin causes impairments in PINK/PARKIN mitophagy: Molecular and cell biology/TDP‐43 JM Casey, D Melandri, C Arber, M Soutar, CJ Holler, T Kukar, AM Isaacs, ... Alzheimer's & Dementia 16, e042104, 2020 | 1 | 2020 |
| A novel gene causing primary familial brain calcification: jAM2 LV Schottlaender, R Abeti, Z Jaunmuktane, M Soutar, J Mckinley, ... European Journal of Neurology 25 (2, SI), 672, 2018 | 1 | 2018 |
| KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy C de Talhouët, N Esteras Gallego, M Soutar, B O’Callaghan, ... bioRxiv, 2023.08. 03.551835, 2023 | | 2023 |
| Haploinsufficiency of progranulin causes cell type specific impairments in PINK1/Parkin mitophagy JM Casey, D Melandri, C Arber, M Soutar, CJ Holler, T Kukar, AM Isaacs, ... Alzheimer's & Dementia 19, e064195, 2023 | | 2023 |
