Mitochondrial Ca2+ signaling T Pathak, M Trebak Pharmacology & therapeutics 192, 112-123, 2018 | 167 | 2018 |
Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels X Zhang, P Xin, RE Yoast, SM Emrich, MT Johnson, T Pathak, JC Benson, ... Cell calcium 91, 102281, 2020 | 96 | 2020 |
A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction X Zhang, T Pathak, R Yoast, S Emrich, P Xin, RM Nwokonko, M Johnson, ... Nature communications 10 (1), 1971, 2019 | 86 | 2019 |
Store-operated calcium entry through Orai is required for transcriptional maturation of the flight circuit in Drosophila T Pathak, T Agrawal, S Richhariya, S Sadaf, G Hasan Journal of Neuroscience 35 (40), 13784-13799, 2015 | 61 | 2015 |
Store-independent modulation of Ca2+ entry through Orai by Septin 7 BK Deb, T Pathak, G Hasan Nature Communications 7 (1), 11751, 2016 | 51 | 2016 |
Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis T Pathak, M Gueguinou, V Walter, C Delierneux, MT Johnson, X Zhang, ... Elife 9, e59686, 2020 | 47 | 2020 |
The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation RE Yoast, SM Emrich, X Zhang, P Xin, V Arige, T Pathak, JC Benson, ... Journal of Biological Chemistry 297 (4), 2021 | 36 | 2021 |
Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity SM Emrich, RE Yoast, P Xin, X Zhang, T Pathak, R Nwokonko, ... Journal of Biological Chemistry 294 (16), 6318-6332, 2019 | 35 | 2019 |
STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma MT Johnson, P Xin, JC Benson, T Pathak, V Walter, SM Emrich, RE Yoast, ... Proceedings of the National Academy of Sciences 119 (1), e2114557118, 2022 | 25 | 2022 |
CRISPR-Cas-Induced Mutants Identify a Requirement for dSTIM in Larval Dopaminergic Cells of Drosophila melanogaster T Pathak, D Trivedi, G Hasan G3: Genes, Genomes, Genetics 7 (3), 923-933, 2017 | 15 | 2017 |
Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells SM Emrich, RE Yoast, X Zhang, AJ Fike, YH Wang, KN Bricker, AY Tao, ... Elife 12, e84708, 2023 | 10 | 2023 |
Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer M Guéguinou, S Ibrahim, J Bourgeais, A Robert, T Pathak, X Zhang, ... Cellular and Molecular Life Sciences 79 (6), 284, 2022 | 10 | 2022 |
The airway smooth muscle sodium/calcium exchanger NCLX is critical for airway remodeling and hyperresponsiveness in asthma MT Johnson, JC Benson, T Pathak, P Xin, AS McKernan, SM Emrich, ... Journal of Biological Chemistry 298 (8), 2022 | 7 | 2022 |
A multiple-oscillator mechanism underlies antigen-induced Ca2+ oscillations in Jurkat T-cells JC Benson, O Romito, AE Abdelnaby, P Xin, T Pathak, SE Weir, V Kirk, ... Journal of Biological Chemistry 299 (11), 2023 | 3 | 2023 |
Regulation of Interorganellar Ca2+ Transfer and NFAT Activation by the Mitochondrial Ca2+ Uniporter RE Yoast, SM Emrich, X Zhang, P Xin, V Arige, T Pathak, JC Benson, ... bioRxiv, 2021.04. 07.438854, 2021 | 2 | 2021 |
NCLX pumps up the heat T Pathak, M Trebak Cell Calcium 92, 102280, 2020 | 2 | 2020 |
Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway T Pathak, JC Benson, MT Johnson, P Xin, AE Abdelnaby, V Walter, ... bioRxiv, 2023 | 1 | 2023 |
L’échangeur ionique NCLX-Un rôle ambivalent dans la chronologie du cancer colorectal M Guéguinou, T Pathak, A Robert, C Vandier, M Trebak, T Lecomte, ... médecine/sciences 37 (2), 124-126, 2021 | 1 | 2021 |
Colorectal adenocarcinomas downregulate the mitochondrial Na+/Ca2+ exchanger NCLX to drive metastatic spread T Pathak, M Gueguinou, V Walter, C Delierneux, MT Johnson, X Zhang, ... bioRxiv, 2020.05. 07.083071, 2020 | 1 | 2020 |
Dichotomous role of the human mitochondrial Na+/Ca2 (+)/Li+ exchanger NCLX in colorectal cancer growth and metastasis (vol 9, e59686, 2020) T Pathak, M Gueguinou, V Walter, C Delierneux, MT Johnson, X Zhang, ... ELIFE 12, 2023 | | 2023 |