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Michele Cioffi
Michele Cioffi
MSL Oncology at MSD
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Year
Extracellular vesicle and particle biomarkers define multiple human cancers
A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ...
Cell 182 (4), 1044-1061. e18, 2020
8042020
A human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids
L Yang, Y Han, BE Nilsson-Payant, V Gupta, P Wang, X Duan, X Tang, ...
Cell stem cell 27 (1), 125-136. e7, 2020
6542020
Cancer stem cells in solid tumors
PC Hermann, S Bhaskar, M Cioffi, C Heeschen
Seminars in cancer biology 20 (2), 77-84, 2010
2522010
Intracellular autofluorescence: a biomarker for epithelial cancer stem cells
I Miranda-Lorenzo, J Dorado, E Lonardo, S Alcala, AG Serrano, ...
Nature methods 11 (11), 1161-1169, 2014
2202014
Inhibition of CD47 effectively targets pancreatic cancer stem cells via dual mechanisms
M Cioffi, S Trabulo, M Hidalgo, E Costello, W Greenhalf, M Erkan, J Kleeff, ...
Clinical cancer research 21 (10), 2325-2337, 2015
1982015
Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells
E Lonardo, M Cioffi, P Sancho, Y Sanchez-Ripoll, SM Trabulo, J Dorado, ...
PLOS ONE 8 (10), e76518, 2013
1792013
EpCAM/CD3-Bispecific T-cell engaging antibody MT110 eliminates primary human pancreatic cancer stem cells
M Cioffi, J Dorado, PA Baeuerle, C Heeschen
Clinical Cancer Research 18 (2), 465-474, 2012
1702012
Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling
A Balic, MD Sørensen, SM Trabulo, B Sainz Jr, M Cioffi, CR Vieira, ...
Molecular cancer therapeutics 13 (7), 1758-1771, 2014
1632014
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment
B Sainz, S Alcala, E Garcia, Y Sanchez-Ripoll, MM Azevedo, M Cioffi, ...
Gut 64 (12), 1921-1935, 2015
1412015
The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells
M Cioffi, SM Trabulo, Y Sanchez-Ripoll, I Miranda-Lorenzo, E Lonardo, ...
Gut 64 (12), 1936-1948, 2015
1362015
Identification of a distinct population of CD133+CXCR4+ cancer stem cells in ovarian cancer
M Cioffi, C D’Alterio, R Camerlingo, V Tirino, C Consales, A Riccio, ...
Scientific reports 5 (1), 10357, 2015
1152015
Concomitant CXCR4 and CXCR7 expression predicts poor prognosis in renal cancer
C D'alterio, C Consales, M Polimeno, R Franco, L Cindolo, L Portella, ...
Current cancer drug targets 10 (7), 772-781, 2010
1072010
MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3
M Cioffi, M Vallespinos-Serrano, SM Trabulo, PJ Fernandez-Marcos, ...
Cell reports 12 (10), 1594-1605, 2015
1052015
Differential role of CD133 and CXCR4 in renal cell carcinoma
C D’Alterio, L Cindolo, L Portella, M Polimeno, C Consales, A Riccio, ...
Cell Cycle 9 (22), 4492-4500, 2010
742010
The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1
M Cioffi, SM Trabulo, M Vallespinos, D Raj, TB Kheir, ML Lin, J Begum, ...
Oncotarget 8 (13), 21609, 2017
732017
Extracellular vesicle–and particle-mediated communication shapes innate and adaptive immune responses
FA Pelissier Vatter, M Cioffi, SJ Hanna, I Castarede, S Caielli, V Pascual, ...
Journal of Experimental Medicine 218 (8), e20202579, 2021
542021
Tumour extracellular vesicles and particles induce liver metabolic dysfunction
G Wang, J Li, L Bojmar, H Chen, Z Li, GC Tobias, M Hu, EA Homan, ...
Nature 618 (7964), 374-382, 2023
382023
Calcium signaling induces a partial EMT
RJ Norgard, JR Pitarresi, R Maddipati, NM Aiello‐Couzo, D Balli, J Li, ...
EMBO reports 22 (9), e51872, 2021
352021
Studying pancreatic cancer stem cell characteristics for developing new treatment strategies
E Lonardo, M Cioffi, P Sancho, S Crusz, C Heeschen
JoVE (Journal of Visualized Experiments), e52801, 2015
342015
Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection
JA Brown, KZ Sanidad, S Lucotti, CM Lieber, RM Cox, ...
Gut microbes 14 (1), 2105609, 2022
302022
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