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Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease M Chen, VO Ona, M Li, RJ Ferrante, KB Fink, S Zhu, J Bian, L Guo, ... Nature medicine 6 (7), 797-801, 2000 | 1355 | 2000 |
Regional and progressive thinning of the cortical ribbon in Huntington’s disease HD Rosas, AK Liu, S Hersch, M Glessner, RJ Ferrante, DH Salat, ... Neurology 58 (5), 695-701, 2002 | 1261 | 2002 |
Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice IA Klement, PJ Skinner, MD Kaytor, H Yi, SM Hersch, HB Clark, ... Cell 95 (1), 41-53, 1998 | 1163 | 1998 |
Nuclear and neuropil aggregates in Huntington’s disease: relationship to neuropathology CA Gutekunst, SH Li, H Yi, JS Mulroy, S Kuemmerle, R Jones, D Rye, ... Journal of Neuroscience 19 (7), 2522-2534, 1999 | 1079 | 1999 |
A YAC mouse model for Huntington’s disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration JG Hodgson, N Agopyan, CA Gutekunst, BR Leavitt, F LePiane, DJ Smith, ... Neuron 23 (1), 181-192, 1999 | 1037 | 1999 |
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease AW Dunah, H Jeong, A Griffin, YM Kim, DG Standaert, SM Hersch, ... Science 296 (5576), 2238-2243, 2002 | 850 | 2002 |
Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice RJ Ferrante, JK Kubilus, J Lee, H Ryu, A Beesen, B Zucker, K Smith, ... Journal of Neuroscience 23 (28), 9418-9427, 2003 | 824 | 2003 |
Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. AI Levey, SM Hersch, DB Rye, RK Sunahara, HB Niznik, CA Kitt, DL Price, ... Proceedings of the National Academy of Sciences 90 (19), 8861-8865, 1993 | 781 | 1993 |
Resistance of α-synuclein null mice to the parkinsonian neurotoxin MPTP W Dauer, N Kholodilov, M Vila, AC Trillat, R Goodchild, KE Larsen, ... Proceedings of the National Academy of Sciences 99 (22), 14524-14529, 2002 | 722 | 2002 |
The dopamine transporter: immunochemical characterization and localization in brain BJ Ciliax, C Heilman, LL Demchyshyn, ZB Pristupa, E Ince, SM Hersch, ... Journal of Neuroscience 15 (3), 1714-1723, 1995 | 680 | 1995 |
Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy KKL Yung, JP Bolam, AD Smith, SM Hersch, BJ Ciliax, AI Levey Neuroscience 65 (3), 709-730, 1995 | 675 | 1995 |
Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes Y Feng, CA Gutekunst, DE Eberhart, H Yi, ST Warren, SM Hersch Journal of neuroscience 17 (5), 1539-1547, 1997 | 670 | 1997 |
Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease RJ Ferrante, OA Andreassen, BG Jenkins, A Dedeoglu, S Kuemmerle, ... Journal of Neuroscience 20 (12), 4389-4397, 2000 | 654 | 2000 |
Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents SM Hersch, BJ Ciliax, CA Gutekunst, HD Rees, CJ Heilman, KK Yung, ... Journal of Neuroscience 15 (7), 5222-5237, 1995 | 591 | 1995 |
Cerebral cortex and the clinical expression of Huntington's disease: complexity and heterogeneity HD Rosas, DH Salat, SY Lee, AK Zaleta, V Pappu, B Fischl, D Greve, ... Brain 131 (4), 1057-1068, 2008 | 574 | 2008 |
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice VC Wheeler, JK White, CA Gutekunst, V Vrbanac, M Weaver, XJ Li, SH Li, ... Human molecular genetics 9 (4), 503-513, 2000 | 535 | 2000 |
Huntingtin aggregates may not predict neuronal death in Huntington's disease S Kuemmerle, CA Gutekunst, AM Klein, XJ Li, SH Li, MF Beal, SM Hersch, ... Annals of neurology 46 (6), 842-849, 1999 | 510 | 1999 |
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease CL Wellington, LM Ellerby, CA Gutekunst, D Rogers, S Warby, ... Journal of Neuroscience 22 (18), 7862-7872, 2002 | 500 | 2002 |
Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease F Borovecki, L Lovrecic, J Zhou, H Jeong, F Then, HD Rosas, SM Hersch, ... Proceedings of the National Academy of Sciences 102 (31), 11023-11028, 2005 | 497 | 2005 |