FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification IA N Kourtis, RS Moubarak, B Aranda-Orgilles, K Lui, IT Aydin, T Trimarchi ... Nature Cell Biology, 322–332, 2015 | 145 | 2015 |
GAB2—a scaffolding protein in cancer SJ Adams, IT Aydin, JT Celebi Molecular Cancer Research 10 (10), 1265-1270, 2012 | 101 | 2012 |
FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm IT Aydin, RD Melamed, SJ Adams, M Castillo-Martin, A Demir, D Bryk, ... Journal of the National Cancer Institute 106 (6), dju107, 2014 | 93 | 2014 |
Genomic characterization of dysplastic nevi unveils implications for diagnosis of melanoma RD Melamed, IT Aydin, GS Rajan, R Phelps, DN Silvers, KJ Emmett, ... Journal of Investigative Dermatology 137 (4), 905-909, 2017 | 63 | 2017 |
Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation B Badal, A Solovyov, S Di Cecilia, JM Chan, LW Chang, R Iqbal, IT Aydin, ... JCI insight 2 (9), 2017 | 57 | 2017 |
RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice K Schouwey, IT Aydin, F Radtke, F Beermann Oncogene 30 (3), 313-322, 2011 | 42 | 2011 |
Coat color dilution in mice because of inactivation of the melanoma antigen MART‐1 IT Aydin, E Hummler, NPM Smit, F Beermann Pigment cell & melanoma research 25 (1), 37-46, 2012 | 31 | 2012 |
A mart‐1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium IT Aydin, F Beermann Genesis 49 (5), 403-409, 2011 | 24 | 2011 |
FBXW 7 regulates a mitochondrial transcription program by modulating MITF F Abbate, B Badal, K Mendelson, IT Aydin, MN Serasinghe, R Iqbal, ... Pigment cell & melanoma research 31 (5), 636-640, 2018 | 15 | 2018 |
Alternatively spliced Robo2 isoforms in zebrafish and rat E Dalkic, C Kuscu, C Sucularli, IT Aydin, KC Akcali, O Konu Development Genes and Evolution 216, 555-563, 2006 | 13 | 2006 |
Cloning and expression profile of FLT3 gene during progenitor cell‐dependent liver regeneration IT Aydin, Z Tokcaer, A Dalgic, O Konu, KC Akcali Journal of gastroenterology and hepatology 22 (12), 2181-2188, 2007 | 10 | 2007 |
FBXW7 inactivation in a BrafV600E-driven mouse model leads to melanoma development IT Aydin, F Abbate, GS Rajan, B Badal, I Aifantis, G Desman, JT Celebi Pigment cell & melanoma research 30 (6), 571, 2017 | 8 | 2017 |
Melanocyte and RPE‐specific expression in transgenic mice by mouse MART‐1/Melan‐A/mlana regulatory sequences IT Aydin, F Beermann Pigment cell & melanoma research 22 (6), 854-856, 2009 | 6 | 2009 |
Expression from a bacterial artificial chromosome containing the Dct gene locus F Murisier, IT Aydin, S Guichard, S Brunschwiler, F Beermann Pigment cell & melanoma research 21 (2), 212-215, 2008 | 3 | 2008 |
AORTIC VASCULAR SMOOTH MUCLE CELL APOPTOSIS IN PATIENTS WITH TYPE-A AORTIC DISSECTION AR AKAR, KC AKÇALI, S DURDU, IT AYDIN, F ÇİVRİL, R TAŞÖZ, ... Turkish Journal of Vascular Surgery 14 (2), 2005 | 3 | 2005 |
First-in-human phase Ib study of ATRC-101, an engineered version of a patient-derived antibody targeting a tumor-restricted ribonucleoprotein complex. JE Benjamin, N Higgins, C Millward, J Defalco, A Manning-Bog, IT Aydin, ... Journal of Clinical Oncology 38 (15_suppl), TPS3168-TPS3168, 2020 | 2 | 2020 |
Expressional and functional profile of TRPC gene family in aging rat aorta Y Erac, C Selli, IT Aydin, B Kosova, CK Akcali, M Tosun Blackwell Publishing, 2006 | 2 | 2006 |
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101 A Scholz, J DeFalco, Y Leung, IT Aydin, CJ Czupalla, W Cao, D Santos, ... Proceedings of the National Academy of Sciences 119 (19), e2123483119, 2022 | 1 | 2022 |
Abstract CT203: First-in-human phase 1b study of ATRC-101, a patient-derived antibody with a tumor-specific target, as monotherapy or in combination with pembrolizumab, in … JE Benjamin, N Higgins, C Millward, J DeFalco, A Manning-Bog, IT Aydin, ... Cancer Research 81 (13_Supplement), CT203-CT203, 2021 | 1 | 2021 |
A human H1-HBB11-GFP reporter embryonic stem cell line (WAe001-A-2) generated using TALEN-based genome editing V Alexeeva, IT Aydin, C Schaniel, AW Stranahan, SL D'Souza, JJ Bieker Stem cell research 45, 101837, 2020 | 1 | 2020 |