Direct Catalytic Enantio‐and Diastereoselective Mannich Reaction of Isocyanoacetates and Ketimines I Ortín, DJ Dixon Angewandte Chemie International Edition 53 (13), 3462-3465, 2014 | 124 | 2014 |
Direct Catalytic Enantio‐and Diastereoselective Ketone Aldol Reactions of Isocyanoacetates R de la Campa, I Ortín, DJ Dixon Angewandte Chemie 127 (16), 4977-4980, 2015 | 98 | 2015 |
Privileged scaffolds in synthesis: 2, 5-piperazinediones as templates for the preparation of structurally diverse heterocycles JF González, I Ortín, E de la Cuesta, JC Menéndez Chemical Society Reviews 41 (21), 6902-6915, 2012 | 72 | 2012 |
Catalytic enantio-and diastereoselective Mannich reaction of α-substituted isocyanoacetates and ketimines R de la Campa, ADG Yamagata, I Ortín, A Franchino, AL Thompson, ... Chemical Communications 52 (70), 10632-10635, 2016 | 62 | 2016 |
Mechanistic Investigations into the Enantioselective Conia‐Ene Reaction Catalyzed by Cinchona‐Derived Amino Urea Pre‐Catalysts and CuI F Sladojevich, ÁL Fuentes de Arriba, I Ortín, T Yang, A Ferrali, RS Paton, ... Chemistry-A European Journal 19 (42), 14286-14295, 2013 | 39 | 2013 |
Pyrazino [1, 2-b] isoquinolines: synthesis and study of their cytostatic and cytotoxic properties I Ortín, JF González, E de la Cuesta, C Manguan-García, R Perona, ... Bioorganic & medicinal chemistry 16 (19), 9065-9078, 2008 | 38 | 2008 |
Synthesis of a novel tetrahydroisoquinoline pentacyclic framework I Ortín, JF González, E de la Cuesta, C Avendano Tetrahedron 65 (11), 2201-2211, 2009 | 19 | 2009 |
Cytotoxicity of new pyrazino [1, 2-b] isoquinoline and 6, 15-iminoisoquino [3, 2-b] 3-benzazocine compounds I Ortín, JF González, E de la Cuesta, C Avendaño Bioorganic & medicinal chemistry 18 (18), 6813-6821, 2010 | 14 | 2010 |
C (3)-alkylation and cyclization of pyrazino [1, 2-b] isoquinolin-4-ones I Ortín, JF González, E de la Cuesta, C Avendaño Tetrahedron 65 (48), 9944-9951, 2009 | 13 | 2009 |
Cytotoxicity mechanisms of pyrazino [1, 2-b] isoquinoline-4-ones and SAR studies I Ortín, JF González, E de la Cuesta, C Manguan-García, R Perona, ... Bioorganic & medicinal chemistry 17 (23), 8040-8047, 2009 | 11 | 2009 |
Synthesis of tetramic acids with a benzo[f]indolizine skeleton. Transannular rearrangements in pyrazino[1,2-b]isoquinolin-4-ones I Ortín, JF González, E de la Cuesta, C Avendaño Tetrahedron 66 (45), 8707-8713, 2010 | 6 | 2010 |
Reactions promoted by [hydroxy (tosyloxy) iodo] benzene in pyrazino [1, 2–b] isoquinolines I Ortín, JF González, E de la Cuesta, C Avendaño Tetrahedron 66 (3), 646-652, 2010 | 4 | 2010 |
Multi-gram synthesis of precursors of bibrachial diaza-paracyclophanes. Complexes with Zn 2, Cu 2 and Co 2 ions C Avendaño, E de la Cuesta, L Huck, I Ortín, J Francisco ARKIVOC 3, 200-211, 2010 | 3 | 2010 |
Supplementary Material Multi-gram synthesis of precursors of bibrachial diaza-paracyclophanes. Complexes with Zn 2, Cu 2 and Co 2 ions C Avendaño, E de la Cuesta, L Huck, I Ortín, JF González ARKIVOC 3, S1-S15, 2011 | | 2011 |
Pirazino [1, 2-b] isoquinolinas: síntesis, manipulación estructural y actividad biológica IO Remón | | 2010 |
CYTOTOXICITY MECHANISMS OF PYRAZINO [1, 2-b] ISOQUINOLINE-4-ONE DERIVATIVES AND SAR STUDIES I Ortin, J Francisco Gonzalez, E de la Cuesta, C Manguan-Garcia, ... DRUGS OF THE FUTURE 34, 169-169, 2009 | | 2009 |