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Mercedes Tkach
Mercedes Tkach
Verified email at curie.fr
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ...
Journal of extracellular vesicles 7 (1), 1535750, 2018
82902018
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
J Kowal, G Arras, M Colombo, M Jouve, JP Morath, B Primdal-Bengtson, ...
Proceedings of the National Academy of Sciences 113 (8), E968-E977, 2016
31312016
Communication by extracellular vesicles: where we are and where we need to go
M Tkach, C Théry
Cell 164 (6), 1226-1232, 2016
30562016
Biogenesis and secretion of exosomes
J Kowal, M Tkach, C Théry
Current opinion in cell biology 29, 116-125, 2014
18202014
Qualitative differences in T‐cell activation by dendritic cell‐derived extracellular vesicle subtypes
M Tkach, J Kowal, AE Zucchetti, L Enserink, M Jouve, D Lankar, ...
The EMBO journal 36 (20), 3012-3028, 2017
3252017
Why the need and how to approach the functional diversity of extracellular vesicles
M Tkach, J Kowal, C Théry
Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018
3242018
Transmission of innate immune signaling by packaging of cGAMP in viral particles
M Gentili, J Kowal, M Tkach, T Satoh, X Lahaye, C Conrad, M Boyron, ...
Science 349 (6253), 1232-1236, 2015
3002015
Extracellular vesicles containing ACE2 efficiently prevent infection by SARS‐CoV‐2 Spike protein‐containing virus
F Cocozza, N Névo, E Piovesana, X Lahaye, J Buchrieser, O Schwartz, ...
Journal of extracellular vesicles 10 (2), e12050, 2020
1172020
Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3
W Béguelin, MC Díaz Flaqué, CJ Proietti, F Cayrol, MA Rivas, M Tkach, ...
Molecular and cellular biology 30 (23), 5456-5472, 2010
1172010
p42/p44 MAPK-mediated Stat3 Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth
M Tkach, C Rosemblit, MA Rivas, CJ Proietti Anastasi, MC Díaz Flaqué, ...
Bioscientifica, 2013
992013
Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance
RI Cordo Russo, W Beguelin, D Flaqué, CJ Proietti, L Venturutti, ...
Oncogene 34 (26), 3413-3428, 2015
612015
Dendritic cell extracellular vesicles
J Kowal, M Tkach
International review of cell and molecular biology 349, 213-249, 2019
562019
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells
M Tkach, L Coria, C Rosemblit, MA Rivas, CJ Proietti, MC Díaz Flaqué, ...
The Journal of Immunology 189 (3), 1162-1172, 2012
552012
Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome
M Tkach, J Thalmensi, E Timperi, P Gueguen, N Névo, E Grisard, P Sirven, ...
Proceedings of the National Academy of Sciences 119 (17), e2107394119, 2022
512022
Small interfering RNA targeted to IGF-IR delays tumor growth and induces proinflammatory cytokines in a mouse breast cancer model
T Durfort, M Tkach, MI Meschaninova, MA Rivas, PV Elizalde, ...
PLoS One 7 (1), e29213, 2012
512012
Transactivation of ErbB-2 induced by tumor necrosis factor α promotes NF-κB activation and breast cancer cell proliferation
MA Rivas, M Tkach, W Beguelin, CJ Proietti, C Rosemblit, EH Charreau, ...
Breast cancer research and treatment 122 (1), 111-124, 2010
462010
Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer …
MC Díaz Flaqué, NM Galigniana, W Béguelin, R Vicario, CJ Proietti, ...
Breast Cancer Research 15, 1-24, 2013
452013
Unbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV‐1 infection
L Martin‐Jaular, N Nevo, JP Schessner, M Tkach, M Jouve, F Dingli, ...
The EMBO Journal 40 (8), e105492, 2021
382021
Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth
F Izzo, F Mercogliano, L Venturutti, M Tkach, G Inurrigarro, R Schillaci, ...
Breast Cancer Research 16, 1-17, 2014
382014
A Brucella spp. protease inhibitor limits antigen lysosomal proteolysis, increases cross-presentation, and enhances CD8+ T cell responses
LM Coria, AE Ibanez, M Tkach, F Sabbione, L Bruno, MV Carabajal, ...
The Journal of Immunology 196 (10), 4014-4029, 2016
322016
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