Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7 F Sierro, C Biben, L Martínez-Muñoz, M Mellado, RM Ransohoff, M Li, ... Proceedings of the National Academy of Sciences 104 (37), 14759-14764, 2007 | 781 | 2007 |
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4 M Schiraldi, A Raucci, LM Muñoz, E Livoti, B Celona, E Venereau, ... Journal of experimental medicine 209 (3), 551-563, 2012 | 707 | 2012 |
The chemokine SDF‐lα triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway AJ Vila‐Coro, JM Rodríguez‐Frade, AM De Ana, MAC Moreno‐Ortíz, ... The FASEB Journal 13 (13), 1699-1710, 1999 | 686 | 1999 |
Chemokine receptor homo-or heterodimerization activates distinct signaling pathways M Mellado, JM Rodríguez-Frade, AJ Vila-Coro, S Fernández, AM de Ana, ... The EMBO journal 20 (10), 2497-2507, 2001 | 558 | 2001 |
Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation M Mellado, JM Rodríguez-Frade, S Mañes, C Martínez-A Annual review of immunology 19 (1), 397-421, 2001 | 515 | 2001 |
CCL2 shapes macrophage polarization by GM-CSF and M-CSF: identification of CCL2/CCR2-dependent gene expression profile E Sierra-Filardi, C Nieto, A Dominguez-Soto, R Barroso, ... The Journal of Immunology 192 (8), 3858-3867, 2014 | 494 | 2014 |
CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity Á Teijeira, S Garasa, M Gato, C Alfaro, I Migueliz, A Cirella, C de Andrea, ... Immunity 52 (5), 856-871. e8, 2020 | 480 | 2020 |
The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2 JM Rodríguez-Frade, AJ Vila-Coro, A Martín de Ana, JP Albar, ... Proceedings of the National Academy of Sciences 96 (7), 3628-3633, 1999 | 312 | 1999 |
Role of the PI3K regulatory subunit in the control of actin organization and cell migration C Jiménez, RA Portela, M Mellado, JM Rodríguez-Frade, J Collard, ... The Journal of cell biology 151 (2), 249-262, 2000 | 296 | 2000 |
Expression of functional chemokine receptors CXCR3 and CXCR4 on human melanoma cells MM Robledo, RA Bartolomé, N Longo, JM Rodrıguez-Frade, M Mellado, ... Journal of Biological Chemistry 276 (48), 45098-45105, 2001 | 294 | 2001 |
DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production E Caparrós, P Munoz, E Sierra-Filardi, D Serrano-Gómez, ... Blood 107 (10), 3950-3958, 2006 | 293 | 2006 |
T cell migration in rheumatoid arthritis M Mellado, L Martinez-Munoz, G Cascio, P Lucas, JL Pablos, ... Frontiers in immunology 6, 384, 2015 | 289 | 2015 |
Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis M Nieto, JMR Frade, D Sancho, M Mellado, C Martinez-A, ... The Journal of experimental medicine 186 (1), 153-158, 1997 | 272 | 1997 |
Structures of T cell immunoglobulin mucin protein 4 show a metal-Ion-dependent ligand binding site where phosphatidylserine binds C Santiago, A Ballesteros, L Martínez-Muñoz, M Mellado, GG Kaplan, ... Immunity 27 (6), 941-951, 2007 | 253 | 2007 |
Identification of amino acid residues crucial for chemokine receptor dimerization P Hernanz-Falcon, JM Rodríguez-Frade, A Serrano, D Juan, A Del Sol, ... Nature immunology 5 (2), 216-223, 2004 | 232 | 2004 |
Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells. JM Frade, M Mellado, G del Real, JC Gutierrez-Ramos, P Lind, ... Journal of immunology (Baltimore, Md.: 1950) 159 (11), 5576-5584, 1997 | 225 | 1997 |
CXCR3 chemokine receptor distribution in normal and inflamed tissues: expression on activated lymphocytes, endothelial cells, and dendritic cells MÁ García-López, F Sánchez-Madrid, JM Rodríguez-Frade, M Mellado, ... Laboratory investigation 81 (3), 409-418, 2001 | 209 | 2001 |
Influence of the CCR2-V64I Polymorphism on Human Immunodeficiency Virus Type 1 Coreceptor Activity and on Chemokine Receptor Function of CCR2b, CCR3 … B Lee, BJ Doranz, S Rana, Y Yi, M Mellado, JMR Frade, C Martinez-A, ... Journal of virology 72 (9), 7450-7458, 1998 | 206 | 1998 |
Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1α-induced lymphocyte polarization and chemotaxis M Vicente-Manzanares, M Rey, DR Jones, D Sancho, M Mellado, ... The Journal of Immunology 163 (7), 4001-4012, 1999 | 192 | 1999 |
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization AJ Vila-Coro, M Mellado, A Martin de Ana, P Lucas, G Del Real, ... Proceedings of the National Academy of Sciences 97 (7), 3388-3393, 2000 | 186 | 2000 |