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Asier Unciti-Broceta
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Palladium-mediated intracellular chemistry
RM Yusop, A Unciti-Broceta, EMV Johansson, RM Sánchez-Martín, ...
Nature Chemistry 3 (3), 239-243, 2011
4962011
Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach
JT Weiss, JC Dawson, KG Macleod, W Rybski, C Fraser, ...
Nature communications 5 (1), 3277, 2014
3142014
Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis
M Sancho-Albero, B Rubio-Ruiz, AM Pérez-López, V Sebastián, ...
Nature catalysis 2 (10), 864-872, 2019
2302019
Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine
JT Weiss, JC Dawson, C Fraser, W Rybski, C Torres-Sánchez, M Bradley, ...
Journal of medicinal chemistry 57 (12), 5395-5404, 2014
2062014
AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective: Miniperspective
SH Myers, VG Brunton, A Unciti-Broceta
Journal of medicinal chemistry 59 (8), 3593-3608, 2016
1992016
Gold‐triggered uncaging chemistry in living systems
AM Pérez‐López, B Rubio‐Ruiz, V Sebastián, L Hamilton, C Adam, ...
Angewandte Chemie International Edition 56 (41), 12548-12552, 2017
1562017
Small molecule kinase inhibitor drugs (1995–2021): medical indication, pharmacology, and synthesis
CC Ayala-Aguilera, T Valero, A Lorente-Macias, DJ Baillache, S Croke, ...
Journal of Medicinal Chemistry 65 (2), 1047-1131, 2021
1462021
Synthesis of polystyrene microspheres and functionalization with Pd0 nanoparticles to perform bioorthogonal organometallic chemistry in living cells
A Unciti-Broceta, EMV Johansson, RM Yusop, RM Sánchez-Martín, ...
nature protocols 7 (6), 1207-1218, 2012
1362012
Efficient palladium-triggered release of vorinostat from a bioorthogonal precursor
B Rubio-Ruiz, JT Weiss, A Unciti-Broceta
Journal of Medicinal Chemistry 59 (21), 9974-9980, 2016
1122016
Bright insights into palladium-triggered local chemotherapy
TL Bray, M Salji, A Brombin, AM Pérez-López, B Rubio-Ruiz, ...
Chemical Science 9 (37), 7354-7361, 2018
852018
Synthesis, penetrability and intracellular targeting of fluorescein-tagged peptoids and peptide–peptoid hybrids
A Unciti-Broceta, F Diezmann, CY Ou-Yang, MA Fara, M Bradley
Bioorganic & medicinal chemistry 17 (3), 959-966, 2009
822009
Palladium-Mediated Dealkylation of N-Propargyl-Floxuridine as a Bioorthogonal Oxygen-Independent Prodrug Strategy
JT Weiss, NO Carragher, A Unciti-Broceta
Scientific reports 5 (1), 9329, 2015
782015
Transition metal catalysts for the bioorthogonal synthesis of bioactive agents
MON van de L'Isle, MC Ortega-Liebana, A Unciti-Broceta
Current opinion in chemical biology 61, 32-42, 2021
692021
Rapid discovery and structure–activity relationships of pyrazolopyrimidines that potently suppress breast cancer cell growth via SRC kinase inhibition with exceptional …
C Fraser, JC Dawson, R Dowling, DR Houston, JT Weiss, AF Munro, ...
Journal of medicinal chemistry 59 (10), 4697-4710, 2016
612016
Cationic lipids
A Unciti-Broceta, A Liberska, M Bradley
US Patent 8,759,104, 2014
592014
Bioorthogonal uncaging of the active metabolite of irinotecan by palladium‐functionalized microdevices
C Adam, AM Pérez‐López, L Hamilton, B Rubio‐Ruiz, TL Bray, D Sieger, ...
Chemistry–A European Journal 24 (63), 16783-16790, 2018
572018
ALDH1 bio-activates nifuroxazide to eradicate ALDHHigh melanoma-initiating cells
S Sarvi, R Crispin, Y Lu, L Zeng, TD Hurley, DR Houston, ...
Cell chemical biology 25 (12), 1456-1469. e6, 2018
502018
Next-generation phenotypic screening
SJ Warchal, A Unciti-Broceta, NO Carragher
Future medicinal chemistry 8 (11), 1331-1347, 2016
502016
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
JDG Leach, N Vlahov, P Tsantoulis, RA Ridgway, DJ Flanagan, K Gilroy, ...
Nature communications 12 (1), 3464, 2021
442021
Recent developments in anticancer kinase inhibitors based on the pyrazolo [3, 4-d] pyrimidine scaffold
DJ Baillache, A Unciti-Broceta
RSC medicinal chemistry 11 (10), 1112-1135, 2020
382020
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