Carlos Santos-Ocaña
Carlos Santos-Ocaña
Professor of Cell Biology
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COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
SF Heeringa, G Chernin, M Chaki, W Zhou, AJ Sloan, Z Ji, LX Xie, ...
The Journal of clinical investigation 121 (5), 2013-2024, 2011
Biosynthesis of ascorbic acid in kidney bean. L-Galactono-γ-lactone dehydrogenase is an intrinsic protein located at the mitochondrial inner membrane
E Siendones, JA González-Reyes, C Santos-Ocana, P Navas, F Córdoba
Plant Physiology 120 (3), 907-912, 1999
Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis
JM López-Martín, L Salviati, E Trevisson, G Montini, S DiMauro, C Quinzii, ...
Human molecular genetics 16 (9), 1091-1097, 2007
Uptake of exogenous coenzyme Q and transport to mitochondria is required for BC 1 complex stability in yeastcoq mutants
C Santos-Ocaña, TQ Do, S Padilla, P Navas, CF Clarke
Journal of Biological Chemistry 277 (13), 10973-10981, 2002
Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency
L Salviati, E Trevisson, MAR Hernandez, A Casarin, V Pertegato, ...
Journal of medical genetics 49 (3), 187-191, 2012
Is coenzyme Q a key factor in aging?
G López-Lluch, JC Rodríguez-Aguilera, C Santos-Ocaña, P Navas
Mechanisms of ageing and development 131 (4), 225-235, 2010
Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity
S Padilla, T Jonassen, MA Jiménez-Hidalgo, DJM Fernández-Ayala, ...
Journal of Biological Chemistry 279 (25), 25995-26004, 2004
Genetic evidence for coenzyme Q requirement in plasma membrane electron transport
C Santos–Ocaña, JM Villalba, F Córdoba, S Padilla, FL Crane, CF Clarke, ...
Journal of bioenergetics and biomembranes 30 (5), 465-475, 1998
Analysis of the sorting signals directing NADH-cytochrome b5 reductase to two locations within yeast mitochondria.
V Haucke, CS Ocana, A Hönlinger, K Tokatlidis, N Pfanner, G Schatz
Molecular and cellular biology 17 (7), 4024-4032, 1997
Coenzyme Q6 and Iron Reduction Are Responsible for the Extracellular Ascorbate Stabilization at the Plasma Membrane ofSaccharomyces cerevisiae
C Santos-Ocaña, F Córdoba, FL Crane, CF Clarke, P Navas
Journal of Biological Chemistry 273 (14), 8099-8105, 1998
Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency
M Doimo, E Trevisson, R Airik, M Bergdoll, C Santos-Ocaña, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (1), 1-6, 2014
Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis
A Casarin, JC Jimenez-Ortega, E Trevisson, V Pertegato, M Doimo, ...
Biochemical and biophysical research communications 372 (1), 35-39, 2008
Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis
S Padilla, UC Tran, M Jiménez-Hidalgo, JM López-Martín, ...
Cellular and molecular life sciences 66 (1), 173, 2009
Mitochondrial responsibility in ageing process: innocent, suspect or guilty
G López-Lluch, C Santos-Ocaña, JA Sánchez-Alcázar, ...
Biogerontology 16 (5), 599-620, 2015
Regulation of coenzyme Q biosynthesis in yeast: a new complex in the block
I González‐Mariscal, E García‐Testón, S Padilla, A Martín‐Montalvo, ...
IUBMB life 66 (2), 63-70, 2014
The phosphatase Ptc7 induces coenzyme Q biosynthesis by activating the hydroxylase Coq7 in yeast
A Martín-Montalvo, I González-Mariscal, T Pomares-Viciana, ...
Journal of Biological Chemistry 288 (39), 28126-28137, 2013
NQR1 controls lifespan by regulating the promotion of respiratory metabolism in yeast
M Jiménez‐Hidalgo, C Santos‐Ocaña, S Padilla, JM Villalba, ...
Aging cell 8 (2), 140-151, 2009
Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis
TPT Nguyen, A Casarin, MA Desbats, M Doimo, E Trevisson, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014
Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p
A Martín-Montalvo, I González-Mariscal, S Padilla, M Ballesteros, ...
Biochemical Journal 440 (1), 107-114, 2011
The regulation of coenzyme q biosynthesis in eukaryotic cells: all that yeast can tell us
I González-Mariscal, E García-Testón, S Padilla, A Martín-Montalvo, ...
Molecular syndromology 5 (3-4), 107-118, 2014
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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