|Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia|
JC Byrd, RR Furman, SE Coutre, IW Flinn, JA Burger, KA Blum, B Grant, ...
New England Journal of Medicine 369 (1), 32-42, 2013
|CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment|
JA Burger, TJ Kipps
Blood 107 (5), 1761-1767, 2006
|Ibrutinib as initial therapy for patients with chronic lymphocytic leukemia|
JA Burger, A Tedeschi, PM Barr, T Robak, C Owen, P Ghia, O Bairey, ...
New England Journal of Medicine 373 (25), 2425-2437, 2015
|Mesenchymal precursor cells in the blood of normal individuals|
NJ Zvaifler, L Marinova-Mutafchieva, G Adams, CJ Edwards, J Moss, ...
Arthritis Research & Therapy 2 (6), 1-12, 2000
|Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell–derived factor-1|
JA Burger, N Tsukada, M Burger, NJ Zvaifler, M Dell'Aquila, TJ Kipps
Blood, The Journal of the American Society of Hematology 96 (8), 2655-2663, 2000
|Three-year follow-up of treatment-naive and previously treated patients with CLL and SLL receiving single-agent ibrutinib|
JC Byrd, RR Furman, SE Coutre, JA Burger, KA Blum, M Coleman, ...
Blood 125 (16), 2497-2506, 2015
|The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo|
S Ponader, SS Chen, JJ Buggy, K Balakrishnan, V Gandhi, WG Wierda, ...
Blood 119 (5), 1182-1189, 2012
|Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma: an open-label, multicentre, phase 1b/2 trial|
S O'Brien, RR Furman, SE Coutre, JP Sharman, JA Burger, KA Blum, ...
The lancet oncology 15 (1), 48-58, 2014
|The microenvironment in mature B-cell malignancies: a target for new treatment strategies|
JA Burger, P Ghia, A Rosenwald, F Caligaris-Cappio
Blood, The Journal of the American Society of Hematology 114 (16), 3367-3375, 2009
|Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells|
JA Burger, M Burger, TJ Kipps
Blood, The Journal of the American Society of Hematology 94 (11), 3658-3667, 1999
|The phosphoinositide 3′-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia|
J Hoellenriegel, SA Meadows, M Sivina, WG Wierda, H Kantarjian, ...
Blood 118 (13), 3603-3612, 2011
|CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers|
JA Burger, A Peled
Leukemia 23 (1), 43-52, 2009
|ICOS deficiency is associated with a severe reduction of CXCR5+ CD4 germinal center Th cells|
L Bossaller, J Burger, R Draeger, B Grimbacher, R Knoth, A Plebani, ...
The Journal of Immunology 177 (7), 4927-4932, 2006
|Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study|
JA Burger, MJ Keating, WG Wierda, E Hartmann, J Hoellenriegel, ...
The Lancet Oncology 15 (10), 1090-1099, 2014
|Phase 2 study of azacytidine plus sorafenib in patients with acute myeloid leukemia and FLT-3 internal tandem duplication mutation|
F Ravandi, ML Alattar, MR Grunwald, MA Rudek, T Rajkhowa, MA Richie, ...
Blood 121 (23), 4655-4662, 2013
|Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion …|
AV Kurtova, K Balakrishnan, R Chen, W Ding, S Schnabl, MP Quiroga, ...
Blood, The Journal of the American Society of Hematology 114 (20), 4441-4450, 2009
|First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia|
F Ravandi, S O'Brien, D Thomas, S Faderl, D Jones, R Garris, S Dara, ...
Blood 116 (12), 2070-2077, 2010
|CXCR4 is a prognostic marker in acute myelogenous leukemia|
AC Spoo, M Lübbert, WG Wierda, JA Burger
Blood 109 (2), 786-791, 2007
|High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation|
JA Burger, MP Quiroga, E Hartmann, A Bürkle, WG Wierda, MJ Keating, ...
Blood, The Journal of the American Society of Hematology 113 (13), 3050-3058, 2009
|Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells|
M Burger, T Hartmann, M Krome, J Rawluk, H Tamamura, N Fujii, ...
Blood 106 (5), 1824-1830, 2005