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Sara Saez-Atienzar
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Genetic risk factors in Parkinson’s disease
KJ Billingsley, S Bandres-Ciga, S Saez-Atienzar, AB Singleton
Cell and tissue research 373, 9-20, 2018
2202018
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
R Chia, MS Sabir, S Bandres-Ciga, S Saez-Atienzar, RH Reynolds, ...
Nature genetics 53 (3), 294-303, 2021
2072021
Cellular senescence and Alzheimer disease: the egg and the chicken scenario
S Saez-Atienzar, E Masliah
Nature Reviews Neuroscience 21 (8), 433-444, 2020
1762020
LRRK2 mediates tubulation and vesicle sorting from lysosomes
L Bonet-Ponce, A Beilina, CD Williamson, E Lindberg, JH Kluss, ...
Science advances 6 (46), eabb2454, 2020
1442020
The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling
S Saez-Atienzar, L Bonet-Ponce, JR Blesa, FJ Romero, MP Murphy, ...
Cell death & disease 5 (8), e1368-e1368, 2014
1102014
Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease
S Bandres-Ciga, S Saez-Atienzar, JJ Kim, MB Makarious, F Faghri, ...
Acta neuropathologica 140, 341-358, 2020
802020
The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease
S Bandres‐Ciga, S Saez‐Atienzar, L Bonet‐Ponce, K Billingsley, D Vitale, ...
Movement Disorders 34 (4), 460-468, 2019
762019
On the mechanism underlying ethanol-induced mitochondrial dynamic disruption and autophagy response
L Bonet-Ponce, S Saez-Atienzar, C da Casa, M Flores-Bellver, JM Barcia, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (7 …, 2015
692015
Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types
S Saez-Atienzar, S Bandres-Ciga, RG Langston, JJ Kim, SW Choi, ...
Science advances 7 (3), eabd9036, 2021
652021
Characterization of mitophagy in the 6-hydoxydopamine Parkinson’s disease model
ME Solesio, S Saez-Atienzar, J Jordán, MF Galindo
Toxicological Sciences 129 (2), 411-420, 2012
592012
The Parkinson’s disease protein LRRK2 interacts with the GARP complex to promote retrograde transport to the trans-Golgi network
A Beilina, L Bonet-Ponce, R Kumaran, JJ Kordich, M Ishida, A Mamais, ...
Cell reports 31 (5), 2020
572020
3‐Nitropropionic acid induces autophagy by forming mitochondrial permeability transition pores rather than activatiing the mitochondrial fission pathway
ME Solesio, S Saez‐Atienzar, J Jordan, MF Galindo
British journal of pharmacology 168 (1), 63-75, 2013
562013
The genetic architecture of Parkinson disease in Spain: characterizing population‐specific risk, differential haplotype structures, and providing etiologic insight
S Bandres‐Ciga, S Ahmed, MS Sabir, C Blauwendraat, ...
Movement Disorders 34 (12), 1851-1863, 2019
542019
Autophagy and mitochondrial alterations in human retinal pigment epithelial cells induced by ethanol: implications of 4-hydroxy-nonenal
M Flores-Bellver, L Bonet-Ponce, JM Barcia, JM Garcia-Verdugo, ...
Cell death & disease 5 (7), e1328-e1328, 2014
502014
Distinct connectivity and functionality of aldehyde dehydrogenase 1a1-positive nigrostriatal dopaminergic neurons in motor learning
J Wu, J Kung, J Dong, L Chang, C Xie, A Habib, S Hawes, N Yang, ...
Cell reports 28 (5), 1167-1181. e7, 2019
492019
Rotenone induces the formation of 4-hydroxynonenal aggresomes. Role of ROS-mediated tubulin hyperacetylation and autophagic flux disruption
L Bonet-Ponce, S Saez-Atienzar, C Da Casa, J Sancho-Pelluz, JM Barcia, ...
Molecular neurobiology 53, 6194-6208, 2016
492016
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
DM Baron, AR Fenton, S Saez-Atienzar, A Giampetruzzi, A Sreeram, ...
Cell reports 39 (1), 2022
442022
Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study
R Chia, S Saez-Atienzar, N Murphy, A Chiò, C Blauwendraat, ...
Proceedings of the National Academy of Sciences 119 (5), e2108672119, 2022
432022
Glutathione-sensitive nanoplatform for monitored intracellular delivery and controlled release of Camptothecin
C Muniesa, V Vicente, M Quesada, S Sáez-Atiénzar, JR Blesa, I Abasolo, ...
RSC advances 3 (35), 15121-15131, 2013
242013
ALDH1A1 regulates postsynaptic μ–opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling
J Pan, J Yu, L Sun, C Xie, L Chang, J Wu, S Hawes, S Saez–Atienzar, ...
Scientific Reports 9 (1), 3602, 2019
232019
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