Structure and dynamics of the active human parathyroid hormone receptor-1 LH Zhao, S Ma, I Sutkeviciute, DD Shen, XE Zhou, PW de Waal, CY Li, ... Science 364 (6436), 148-153, 2019 | 194 | 2019 |
A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus N Varga, I Sutkeviciute, R Ribeiro-Viana, A Berzi, R Ramdasi, A Daghetti, ... Biomaterials 35 (13), 4175-4184, 2014 | 131 | 2014 |
Pseudosaccharide functionalized dendrimers as potent inhibitors of DC-SIGN dependent Ebola pseudotyped viral infection J Luczkowiak, S Sattin, I Sutkeviciute, JJ Reina, M Sánchez-Navarro, ... Bioconjugate chemistry 22 (7), 1354-1365, 2011 | 117 | 2011 |
Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design M Thépaut, C Guzzi, I Sutkeviciute, S Sattin, R Ribeiro-Viana, N Varga, ... Journal of the American Chemical Society 135 (7), 2518-2529, 2013 | 96 | 2013 |
A glycomimetic compound inhibits DC-SIGN-mediated HIV infection in cellular and cervical explant models A Berzi, JJ Reina, R Ottria, I Sutkeviciute, P Antonazzo, ... Aids 26 (2), 127-137, 2012 | 74 | 2012 |
Second generation of fucose-based DC-SIGN ligands: affinity improvement and specificity versus Langerin M Andreini, D Doknic, I Sutkeviciute, JJ Reina, J Duan, E Chabrol, ... Organic & biomolecular chemistry 9 (16), 5778-5786, 2011 | 74 | 2011 |
Selective targeting of dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin (DC‐SIGN) with mannose‐based glycomimetics: synthesis and interaction … N Varga, I Sutkeviciute, C Guzzi, J McGeagh, I Petit‐Haertlein, S Gugliotta, ... Chemistry–A European Journal 19 (15), 4786-4797, 2013 | 70 | 2013 |
Structural insights into emergent signaling modes of G protein–coupled receptors I Sutkeviciute, JP Vilardaga Journal of Biological Chemistry 295 (33), 11626-11642, 2020 | 68 | 2020 |
Rational-differential design of highly specific glycomimetic ligands: targeting DC-SIGN and excluding langerin recognition V Porkolab, E Chabrol, N Varga, S Ordanini, I Sutkevičiu̅tė, ... ACS chemical biology 13 (3), 600-608, 2017 | 66 | 2017 |
PTH/PTHrP receptor signaling, allostery, and structures I Sutkeviciute, LJ Clark, AD White, TJ Gardella, JP Vilardaga Trends in Endocrinology & Metabolism 30 (11), 860-874, 2019 | 64 | 2019 |
Unique DC-SIGN clustering activity of a small glycomimetic: A lesson for ligand design I Sutkeviciute, M Thépaut, S Sattin, A Berzi, J McGeagh, S Grudinin, ... ACS chemical biology 9 (6), 1377-1385, 2014 | 60 | 2014 |
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation AD White, KA Peña, LJ Clark, CS Maria, S Liu, FG Jean-Alphonse, JY Lee, ... Science signaling 14 (703), eabc5944, 2021 | 48 | 2021 |
Ca2+ allostery in PTH-receptor signaling AD White, F Fang, FG Jean-Alphonse, LJ Clark, HJ An, H Liu, Y Zhao, ... Proceedings of the National Academy of Sciences 116 (8), 3294-3299, 2019 | 47 | 2019 |
Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation LJ Clark, J Krieger, AD White, V Bondarenko, S Lei, F Fang, JY Lee, ... Nature chemical biology 16 (10), 1096-1104, 2020 | 40 | 2020 |
Development of C-type lectin-oriented surfaces for high avidity glycoconjugates: towards mimicking multivalent interactions on the cell surface V Porkolab, C Pifferi, I Sutkeviciute, S Ordanini, M Taouai, M Thepaut, ... Organic & Biomolecular Chemistry 18 (25), 4763-4772, 2020 | 39 | 2020 |
Synthesis of a selective inhibitor of a fucose binding bacterial lectin from Burkholderia ambifaria B Richichi, A Imberty, E Gillon, R Bosco, I Sutkeviciute, F Fieschi, C Nativi Organic & Biomolecular Chemistry 11 (24), 4086-4094, 2013 | 37 | 2013 |
Transmission electron microscopy for the evaluation and optimization of crystal growth HP Stevenson, G Lin, CO Barnes, I Sutkeviciute, T Krzysiak, SC Weiss, ... Acta Crystallographica Section D: Structural Biology 72 (5), 603-615, 2016 | 34 | 2016 |
Polyvalent C-glycomimetics based on l-fucose or d-mannose as potent DC-SIGN antagonists B Bertolotti, I Sutkeviciute, M Ambrosini, R Ribeiro-Viana, J Rojo, ... Organic & Biomolecular Chemistry 15 (18), 3995-4004, 2017 | 26 | 2017 |
Synthesis and characterization of linker‐armed fucose‐based glycomimetics D Doknic, M Abramo, I Sutkeviciute, A Reinhardt, C Guzzi, MK Schlegel, ... European Journal of Organic Chemistry 2013 (24), 5303-5314, 2013 | 24 | 2013 |
Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering C Guzzi, P Alfarano, I Sutkeviciute, S Sattin, R Ribeiro-Viana, F Fieschi, ... Organic & Biomolecular Chemistry 14 (1), 335-344, 2016 | 19 | 2016 |