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Joana Bicker
Joana Bicker
Coimbra Institute for Biomedical Imaging and Translational Research; Faculty of Pharmacy of UC
Dirección de correo verificada de ff.uc.pt
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Blood–brain barrier models and their relevance for a successful development of CNS drug delivery systems: a review
J Bicker, G Alves, A Fortuna, A Falcão
European Journal of Pharmaceutics and Biopharmaceutics 87 (3), 409-432, 2014
3032014
Liquid chromatographic methods for the quantification of catecholamines and their metabolites in several biological samples—a review
J Bicker, A Fortuna, G Alves, A Falcao
Analytica chimica acta 768, 12-34, 2013
2052013
ABC transporters in drug-resistant epilepsy: mechanisms of upregulation and therapeutic approaches
K Leandro, J Bicker, G Alves, A Falcão, A Fortuna
Pharmacological research, 2019
572019
A new PAMPA model using an in-house brain lipid extract for screening the blood–brain barrier permeability of drug candidates
J Bicker, G Alves, A Fortuna, P Soares-da-Silva, A Falcão
International journal of pharmaceutics 501 (1-2), 102-111, 2016
542016
Nose-to-brain delivery of levetiracetam after intranasal administration to mice
J Gonçalves, J Bicker, F Gouveia, J Liberal, RC Oliveira, G Alves, ...
International journal of pharmaceutics 564, 329-339, 2019
512019
Development, validation and application of a new HPLC-DAD method for simultaneous quantification of apixaban, dabigatran, edoxaban and rivaroxaban in human plasma
F Gouveia, J Bicker, J Santos, M Rocha, G Alves, A Falcão, A Fortuna
Journal of Pharmaceutical and Biomedical Analysis, 113109, 2020
492020
Timing in drug absorption and disposition: the past, present and future of chronopharmacokinetics
J Bicker, G Alves, A Falcão, A Fortuna
British Journal of Pharmacology, 0
45
Liquid chromatographic methods for the determination of direct oral anticoagulant drugs in biological samples: A critical review
F Gouveia, J Bicker, J Gonçalves, G Alves, A Falcão, A Fortuna
Analytica chimica acta, 2019
342019
Antidepressants and nose-to-brain delivery: drivers, restraints, opportunities and challenges
C Vitorino, S Silva, J Bicker, A Falcão, A Fortuna
Drug discovery today, 2019
302019
A chiral HPLC‐UV method for the quantification of dibenz [b, f] azepine‐5‐carboxamide derivatives in mouse plasma and brain tissue: Eslicarbazepine acetate, carbamazepine and …
A Fortuna, J Bicker, G Alves, A Falcão, P Soares‐da‐Silva
Journal of separation science 34 (12), 1391-1401, 2011
242011
Development and full validation of an innovative HPLC-diode array detection technique to simultaneously quantify lacosamide, levetiracetam and zonisamide in human plasma
J Gonçalves, G Alves, J Bicker, A Falcão, A Fortuna
Bioanalysis 10 (8), 541-557, 2018
232018
Elucidation of the impact of p-glycoprotein and breast cancer resistance protein on the brain distribution of catechol-o-methyltransferase inhibitors
J Bicker, A Fortuna, G Alves, P Soares-da-Silva, A Falcão
Drug Metabolism and Disposition 45 (12), 1282-1291, 2017
232017
Anti-PD-1 immunotherapy in advanced metastatic melanoma: State of the art and future challenges
RS Moreira, J Bicker, F Musicco, A Persichetti, AMPT Pereira
Life sciences 240, 117093, 2020
222020
Nose-to-brain Delivery of Natural Compounds for the Treatment of Central Nervous System Disorders
J Bicker, A Fortuna, G Alves, A Falcão
Current Pharmaceutical Design, 2019
192019
Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective
J Goncalves, J Bicker, G Alves, A Fortuna, A Falcao
Current drug metabolism 19 (12), 1021-1041, 2018
142018
In vitro assessment of the interactions of dopamine β-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein
J Bicker, G Alves, A Fortuna, P Soares-da-Silva, A Falcão
European Journal of Pharmaceutical Sciences 117, 35-40, 2018
92018
Screening of pharmacokinetic properties of fifty dihydropyrimidin (thi) one derivatives using a combo of in vitro and in silico assays
M Matias, A Fortuna, J Bicker, S Silvestre, A Falcão, G Alves
European Journal of Pharmaceutical Sciences 109, 334-346, 2017
92017
Therapeutic drug monitoring of levetiracetam: pharmacokinetic characterization and compliance assessment of epileptic patients
J Goncalves, R Silva, A Almeida, J Bicker, A Silva, F Sales, A Falcao, ...
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 220-220, 2019
2019
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