Peter Linsley
Peter Linsley
Member and Director | Systems Immunology Benaroya Research Institute at Virginia Mason 1201 Ninth
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Gene expression profiling predicts clinical outcome of breast cancer
LJ Van't Veer, H Dai, MJ Van De Vijver, YD He, AAM Hart, M Mao, ...
nature 415 (6871), 530-536, 2002
107212002
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
LP Lim, NC Lau, P Garrett-Engele, A Grimson, JM Schelter, J Castle, ...
Nature 433 (7027), 769-773, 2005
54432005
A microRNA component of the p53 tumour suppressor network
L He, X He, LP Lim, E De Stanchina, Z Xuan, Y Liang, W Xue, L Zender, ...
Nature 447 (7148), 1130-1134, 2007
30542007
Expression profiling reveals off-target gene regulation by RNAi
AL Jackson, SR Bartz, J Schelter, SV Kobayashi, J Burchard, M Mao, B Li, ...
Nature biotechnology 21 (6), 635-637, 2003
28242003
CTLA-4 can function as a negative regulator of T cell activation
TL Walunas, DJ Lenschow, CY Bakker, PS Linsley, GJ Freeman, ...
Immunity 1 (5), 405-413, 1994
23531994
CTLA-4 is a second receptor for the B cell activation antigen B7.
PS Linsley, W Brady, M Urnes, LS Grosmaire, NK Damle, JA Ledbetter
The Journal of experimental medicine 174 (3), 561-569, 1991
19931991
Genetics of gene expression surveyed in maize, mouse and man
EE Schadt, SA Monks, TA Drake, AJ Lusis, N Che, V Colinayo, TG Ruff, ...
Nature 422 (6929), 297-302, 2003
17902003
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
CP Larsen, ET Elwood, DZ Alexander, SC Ritchie, R Hendrix, ...
Nature 381 (6581), 434-438, 1996
16701996
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
RV Parry, JM Chemnitz, KA Frauwirth, AR Lanfranco, I Braunstein, ...
Molecular and cellular biology 25 (21), 9543-9553, 2005
16672005
The role of the CD28 receptor during T cell responses to antigen
PS Linsley, JA Ledbetter
Annual review of immunology 11 (1), 191-212, 1993
16631993
Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer
TR Hughes, M Mao, AR Jones, J Burchard, MJ Marton, KW Shannon, ...
Nature biotechnology 19 (4), 342-347, 2001
15712001
Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.
PS Linsley, W Brady, L Grosmaire, A Aruffo, NK Damle, JA Ledbetter
The Journal of experimental medicine 173 (3), 721-730, 1991
15401991
Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg
DJ Lenschow, Y Zeng, A Montag, W Brady, MG Gibson, PS Linsley, ...
Science 257 (5071), 789-792, 1992
14401992
Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
L Chen, S Ashe, WA Brady, I Hellström, KE Hellström, JA Ledbetter, ...
Cell 71 (7), 1093-1102, 1992
13701992
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
K Berns, EM Hijmans, J Mullenders, TR Brummelkamp, A Velds, ...
Nature 428 (6981), 431-437, 2004
13612004
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
PS Linsley, JAL Greene, W Brady, J Bajorath, JA Ledbetter, R Peach
Immunity 1 (9), 793-801, 1994
10941994
IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.
L Ding, PS Linsley, LY Huang, RN Germain, EM Shevach
The Journal of Immunology 151 (3), 1224-1234, 1993
10841993
Widespread siRNA “off-target” transcript silencing mediated by seed region sequence complementarity
AL Jackson, J Burchard, J Schelter, BN Chau, M Cleary, L Lim, PS Linsley
Rna 12 (7), 1179-1187, 2006
10762006
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
AL Jackson, PS Linsley
Nature reviews Drug discovery 9 (1), 57-67, 2010
10272010
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
G Gabriely, T Wurdinger, S Kesari, CC Esau, J Burchard, PS Linsley, ...
Molecular and cellular biology 28 (17), 5369-5380, 2008
10192008
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Artículos 1–20