Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits G Gerenu, E Martisova, H Ferrero, M Carracedo, T Rantamäki, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (4), 991 …, 2017 | 81 | 2017 |
Propranolol reduces cognitive deficits, amyloid and tau pathology in Alzheimer's transgenic mice M Dobarro, G Gerenu, MJ Ramírez International Journal of Neuropsychopharmacology 16 (10), 2245-2257, 2013 | 79 | 2013 |
Curcumin/Melatonin Hybrid 5-(4-Hydroxy-phenyl)-3-oxo-pentanoic Acid [2-(5-Methoxy-1H-indol-3-yl)-ethyl]-amide Ameliorates AD-Like Pathology in the APP/PS1 … G Gerenu, K Liu, JE Chojnacki, JM Saathoff, P Martínez-Martín, G Perry, ... ACS chemical neuroscience 6 (8), 1393-1399, 2015 | 66 | 2015 |
Effects of early maternal separation on biobehavioral and neuropathological markers of Alzheimer's disease in adult male rats. RMJ Martisova E, Aisa B, Guereñu G Curr Alzheimer Res 10 (4), 420-32, 2013 | 65 | 2013 |
Down‐regulation of glutamatergic terminals (VGLUT1) driven by Aβ in Alzheimer's disease M Rodriguez‐Perdigon, RM Tordera, FJ Gil‐Bea, G Gerenu, MJ Ramirez, ... Hippocampus 26 (10), 1303-1312, 2016 | 44 | 2016 |
Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice FJ Gil-Bea, G Gerenu, B Aisa, LP Kirazov, R Schliebs, MJ Ramírez Neurobiology of disease 48 (3), 439-446, 2012 | 37 | 2012 |
Connecting the brain cholesterol and renin–angiotensin systems: potential role of statins and RAS‐modifying medications in dementia B Petek, M Villa‐Lopez, R Loera‐Valencia, G Gerenu, B Winblad, ... Journal of internal medicine 284 (6), 620-642, 2018 | 34 | 2018 |
Mineralocorticoid receptor activation induces insulin resistance through c‐Jun N‐terminal kinases in response to chronic corticosterone: cognitive implications M Solas, G Gerenu, FJ Gil‐Bea, MJ Ramírez Journal of neuroendocrinology 25 (4), 350-356, 2013 | 33 | 2013 |
The skeletal muscle emerges as a new disease target in amyotrophic lateral sclerosis O Pikatza-Menoio, A Elicegui, X Bengoetxea, N Naldaiz-Gastesi, ... Journal of personalized medicine 11 (7), 671, 2021 | 31 | 2021 |
Early cognitive stimulation compensates for memory and pathological changes in Tg2576 mice G Gerenu, M Dobarro, MJ Ramirez, FJ Gil-Bea Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (6), 837-847, 2013 | 30 | 2013 |
A comprehensive serum lipidome profiling of amyotrophic lateral sclerosis G FernÁndez-Eulate, JÉI Ruiz-Sanz, J Riancho, M ZufirÍa, G GereÑu, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 21 (3-4), 252-262, 2020 | 26 | 2020 |
High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus R Loera-Valencia, E Vazquez-Juarez, A Muñoz, G Gerenu, ... Scientific Reports 11 (1), 3736, 2021 | 23 | 2021 |
Mechanisms involved in BACE upregulation associated to stress E Martisova, M Solas, G Gerenu, F I Milagro, J Campion, M J Ramirez Current Alzheimer Research 9 (7), 822-829, 2012 | 18 | 2012 |
Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation G Gerenu, T Persson, J Goikolea, J Calvo-Garrido, R Loera-Valencia, ... Molecular Psychiatry 26 (4), 1410-1423, 2021 | 14 | 2021 |
Serum Thioredoxin-80 is associated with age, ApoE4, and neuropathological biomarkers in Alzheimer’s disease: a potential early sign of AD J Goikolea, G Gerenu, M Daniilidou, F Mangialasche, P Mecocci, ... Alzheimer's Research & Therapy 14 (1), 37, 2022 | 13 | 2022 |
Defects of nutrient signaling and autophagy in neurodegeneration J Ondaro, H Hernandez-Eguiazu, M Garciandia-Arcelus, ... Frontiers in Cell and Developmental Biology 10, 836196, 2022 | 11 | 2022 |
Senescence plays a role in myotonic dystrophy type 1 M García-Puga, A Saenz-Antoñanzas, G Gerenu, A Arrieta-Legorburu, ... JCI insight 7 (19), 2022 | 8 | 2022 |
Targeting the ubiquitin-proteasome system in limb-girdle muscular dystrophy with CAPN3 mutations J Lasa-Elgarresta, L Mosqueira-Martín, K González-Imaz, ... Frontiers in Cell and Developmental Biology 10, 822563, 2022 | 3 | 2022 |
Biallelic variants in SNUPN cause a limb girdle muscular dystrophy with myofibrillar-like features P Iruzubieta, A Damborenea, M Ioghen, S Bajew, R Fernandez-Torrón, ... Brain, awae046, 2024 | | 2024 |
Elevated cholesterol in ATAD3 mutants is a compensatory mechanism that leads to membrane cholesterol aggregation M Muñoz-Oreja, A Sandoval, O Bruland, D Perez-Rodriguez, ... Brain, awae018, 2024 | | 2024 |