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Manuel Izquierdo Pastor
Manuel Izquierdo Pastor
INVESTIGADOR CIENTIFICO, IIBM ALBERTO SOLS,CSIC-UAM
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p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes.
M Izquierdo, SJ Leevers, CJ Marshall, D Cantrell
The Journal of experimental medicine 178 (4), 1199-1208, 1993
2091993
The regulation and function of p21ras during T-cell activation and growth
M Izquierdo, K Reif, D Cantrell
Immunology Today 16 (3), 159-164, 1995
202*1995
Role of Protein Kinase C in T-Cell Antigen Receptor Regulation of p21ras: Evidence that Two p21ras Regulatory Pathways Coexist in Τ Cells
M Izquierdo, J Downward, JD Graves, DA Cantrell
Molecular and cellular biology 12 (7), 3305-3312, 1992
2001992
Role of diacylglycerol kinase α in the attenuation of receptor signaling
MA Sanjuán, DR Jones, M Izquierdo, I Mérida
The Journal of cell biology 153 (1), 207-220, 2001
1702001
Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes
R Alonso, C Mazzeo, MC Rodríguez, M Marsh, A Fraile-Ramos, V Calvo, ...
Cell Death & Differentiation 18 (7), 1161-1173, 2011
1662011
Diacylglycerol kinase α regulates the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes
R Alonso, MC Rodríguez, J Pindado, E Merino, I Mérida, M Izquierdo
Journal of Biological Chemistry 280 (31), 28439-28450, 2005
1512005
Calcium influx through receptor-operated channel induces mitochondria-triggered paraptotic cell death
E Jambrina, R Alonso, M Alcalde, M del Carmen Rodrıguez, A Serrano, ...
Journal of Biological Chemistry 278 (16), 14134-14145, 2003
1412003
Exosome secretion by eosinophils: A possible role in asthma pathogenesis
C Mazzeo, JA Cañas, MP Zafra, AR Marco, M Fernández-Nieto, V Sanz, ...
Journal of Allergy and Clinical Immunology 135 (6), 1603-1613, 2015
1232015
CD38 ligation results in activation of the Raf-1/mitogen-activated protein kinase and the CD3-zeta/zeta-associated protein-70 signaling pathways in Jurkat T lymphocytes.
M Zubiaur, M Izquierdo, C Terhorst, F Malavasi, J Sancho
Journal of immunology (Baltimore, Md.: 1950) 159 (1), 193-205, 1997
1151997
The growth factor IL-2 activates p21ras proteins in normal human T lymphocytes.
JD Graves, J Downward, M Izquierdo-Pastor, S Rayter, PH Warne, ...
Journal of immunology (Baltimore, Md.: 1950) 148 (8), 2417-2422, 1992
991992
Blocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor
M Izquierdo, A Grandien, LM Criado, S Robles, E Leonardo, JP Albar, ...
The EMBO journal 18 (1), 156-166, 1999
881999
Degradation of cellular mRNA is a general early apoptosis‐induced event
MJ Del Prete, MS Robles, A Guío, C Martínez‐A, M Izquierdo, ...
The FASEB journal 16 (14), 2003-2005, 2002
852002
A novel functional cell surface dimer (Kp43) expressed by natural killer cells and gamma/delta TCR+ T lymphocytes. II. Modulation of natural killer cytotoxicity by anti-Kp43 …
J Aramburu, MA Balboa, M Izquierdo, M Lopez-Botet
Journal of immunology (Baltimore, Md.: 1950) 147 (2), 714-721, 1991
831991
Protein kinase C inhibits CD95 (Fas/APO-1)-mediated apoptosis by at least two different mechanisms in Jurkat T cells
C Ruiz-Ruiz, G Robledo, J Font, M Izquierdo, A López-Rivas
The Journal of Immunology 163 (9), 4737-4746, 1999
821999
Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes
C Mazzeo, V Calvo, R Alonso, I Mérida, M Izquierdo
Cell Death & Differentiation 23 (1), 99-109, 2016
762016
Role of microvesicles in the spread of herpes simplex virus 1 in oligodendrocytic cells
R Bello-Morales, B Praena, C de la Nuez, MT Rejas, M Guerra, ...
Journal of virology 92 (10), 10.1128/jvi. 00088-18, 2018
732018
Exosomes from eosinophils autoregulate and promote eosinophil functions
JA Cañas, B Sastre, C Mazzeo, M Fernández-Nieto, JM Rodrigo-Muñoz, ...
Journal of Leucocyte Biology 101 (5), 1191-1199, 2017
722017
The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor.
M Izquierdo, S Bowden, D Cantrell
The Journal of experimental medicine 180 (1), 401-406, 1994
711994
A new role of diacylglycerol kinase α on the secretion of lethal exosomes bearing Fas ligand during activation-induced cell death of T lymphocytes
R Alonso, C Mazzeo, I Mérida, M Izquierdo
Biochimie 89 (2), 213-221, 2007
682007
Activation of protein kinase C attenuates early signals in Fas‐mediated apoptosis
MDC Ruiz‐Ruiz, M Izquierdo, G de Murcia, A López‐Rivas
European journal of immunology 27 (6), 1442-1450, 1997
661997
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