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Kristina Herbert
Kristina Herbert
University of Texas MD Anderson Cancer Center
Dirección de correo verificada de mdanderson.org
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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ...
Nature 586 (7827), 113-119, 2020
7272020
MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells
X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune, Y Yamamoto, K Sakai, ...
Cell reports 34 (2), 2021
3412021
Sequence-resolved detection of pausing by single RNA polymerase molecules
KM Herbert, A La Porta, BJ Wong, RA Mooney, KC Neuman, R Landick, ...
Cell 125 (6), 1083-1094, 2006
3262006
Single-molecule studies of RNA polymerase: motoring along
KM Herbert, WJ Greenleaf, SM Block
Annu. Rev. Biochem. 77, 149-176, 2008
2432008
Solution structure of an A-tract DNA bend
D MacDonald, K Herbert, X Zhang, T Polgruto, P Lu
Journal of molecular biology 306 (5), 1081-1098, 2001
1932001
E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase
KM Herbert, J Zhou, RA Mooney, A La Porta, R Landick, SM Block
Journal of molecular biology 399 (1), 17-30, 2010
1352010
Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile
KM Herbert, G Pimienta, SJ DeGregorio, A Alexandrov, JA Steitz
Cell reports 5 (4), 1070-1081, 2013
1212013
Pathways and intermediates in forced unfolding of spectrin repeats
SM Altmann, RG Grünberg, PF Lenne, J Ylänne, A Raae, K Herbert, ...
Structure 10 (8), 1085-1096, 2002
962002
A large-scale drug repositioning survey for SARS-CoV-2 antivirals
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, ...
BioRxiv, 2020.04. 16.044016, 2020
912020
A compound that inhibits the HOP-Hsp90 complex formation and has unique killing effects in breast cancer cell lines
G Pimienta, KM Herbert, L Regan
Molecular Pharmaceutics, 2011
702011
Sensor sensibility—HIV-1 and the innate immune response
X Yin, S Langer, Z Zhang, KM Herbert, S Yoh, R König, SK Chanda
Cells 9 (1), 254, 2020
652020
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses
S Langer, C Hammer, K Hopfensperger, L Klein, D Hotter, PD De Jesus, ...
Elife 8, e41930, 2019
652019
A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting
KM Herbert, SK Sarkar, M Mills, HCD De la Herran, KC Neuman, JA Steitz
rna 22 (2), 175-183, 2016
592016
Noncanonical function of DGCR8 controls mESC exit from pluripotency
D Cirera-Salinas, J Yu, M Bodak, RP Ngondo, KM Herbert, C Ciaudo
Journal of Cell Biology 216 (2), 355-366, 2017
472017
A tale of two RNAs during viral infection: how viruses antagonize mRNAs and small non-coding RNAs in the host cell
KM Herbert, A Nag
Viruses 8 (6), 154, 2016
292016
Consideration of Epstein-Barr virus-encoded noncoding RNAs EBER1 and EBER2 as a functional backup of viral oncoprotein latent membrane protein 1
KM Herbert, G Pimienta
MBio 7 (1), 10.1128/mbio. 01926-15, 2016
212016
Molecule by molecule, the physics and chemistry of life: SMB 2007
SM Block, MH Larson, WJ Greenleaf, KM Herbert, NR Guydosh, ...
Nature chemical biology 3 (4), 193-197, 2007
62007
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells
A Rodriguez-Frandsen, L Martin-Sancho, AP Gounder, MW Chang, ...
Journal of virology 94 (4), 10.1128/jvi. 01410-19, 2020
52020
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells (preprint)
X Yin, L Riva, Y Pu, L Martin-Sancho, J Kanamune, Y Yamamoto, K Sakai, ...
2020
Sequence Dependent Pausing by RNA Polymerase: A Single Molecule Optical Trapping Study
KM Herbert
Stanford University, 2008
2008
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Artículos 1–20