Matthew Redinbo
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Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
MR Redinbo, L Stewart, P Kuhn, JJ Champoux, WGJ Hol
Science 279 (5356), 1504-1513, 1998
The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity
RE Watkins, GB Wisely, LB Moore, JL Collins, MH Lambert, SP Williams, ...
Science 292 (5525), 2329-2333, 2001
A model for the mechanism of human topoisomerase I
L Stewart, MR Redinbo, X Qiu, WGJ Hol, JJ Champoux
Science 279 (5356), 1534-1541, 1998
Alleviating cancer drug toxicity by inhibiting a bacterial enzyme
BD Wallace, H Wang, KT Lane, JE Scott, J Orans, JS Koo, M Venkatesh, ...
Science 330 (6005), 831-835, 2010
Crystal structure of an ancient protein: evolution by conformational epistasis
EA Ortlund, JT Bridgham, MR Redinbo, JW Thornton
Science 317 (5844), 1544-1548, 2007
Regulation of cyp3a gene transcription by the pregnane x receptor
B Goodwin, MR Redinbo, SA Kliewer
Annual review of pharmacology and toxicology 42 (1), 1-23, 2002
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4
M Venkatesh, S Mukherjee, H Wang, H Li, K Sun, AP Benechet, Z Qiu, ...
Immunity 41 (2), 296-310, 2014
2.1 Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin,
RE Watkins, JM Maglich, LB Moore, GB Wisely, SM Noble, ...
Biochemistry 42 (6), 1430-1438, 2003
Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor
RE Watkins, PR Davis-Searles, MH Lambert, MR Redinbo
Journal of molecular biology 331 (4), 815-828, 2003
Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme
S Bencharit, CL Morton, Y Xue, PM Potter, MR Redinbo
Nature Structural & Molecular Biology 10 (5), 349-356, 2003
Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole
H Huang, H Wang, M Sinz, M Zoeckler, J Staudinger, MR Redinbo, ...
Oncogene 26 (2), 258-268, 2007
Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin
JE Chrencik, J Orans, LB Moore, Y Xue, L Peng, JL Collins, GB Wisely, ...
Molecular Endocrinology 19 (5), 1125-1134, 2005
Keynote review: Mammalian carboxylesterases: From drug targets to protein therapeutics
MR Redinbo, PM Potter
Drug discovery today 10 (5), 313-325, 2005
The role of the microbiome in cancer development and therapy
AP Bhatt, MR Redinbo, SJ Bultman
CA: a cancer journal for clinicians 67 (4), 326-344, 2017
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
G Schaaf, EA Ortlund, KR Tyeryar, CJ Mousley, KE Ile, TA Garrett, J Ren, ...
Molecular cell 29 (2), 191-206, 2008
Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
EA Ortlund, Y Lee, IH Solomon, JM Hager, R Safi, Y Choi, Z Guan, ...
Nature structural & molecular biology 12 (4), 357-363, 2005
Structural insights into CPT-11 activation by mammalian carboxylesterases
S Bencharit, CL Morton, EL Howard-Williams, MK Danks, PM Potter, ...
Nature structural biology 9 (5), 337-342, 2002
Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7
MJ Miley, AK Zielinska, JE Keenan, SM Bratton, A Radominska-Pandya, ...
Journal of molecular biology 369 (2), 498-511, 2007
Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA
MR Redinbo, JJ Champoux, WGJ Hol
Biochemistry 39 (23), 6832-6840, 2000
Plastocyanin: structural and functional analysis
MR Redinbo, TO Yeates, S Merchant
Journal of bioenergetics and biomembranes 26 (1), 49-66, 1994
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