Matthew Redinbo
Title
Cited by
Cited by
Year
Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
MR Redinbo, L Stewart, P Kuhn, JJ Champoux, WGJ Hol
Science 279 (5356), 1504-1513, 1998
10141998
The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity
RE Watkins, GB Wisely, LB Moore, JL Collins, MH Lambert, SP Williams, ...
Science 292 (5525), 2329-2333, 2001
8572001
A model for the mechanism of human topoisomerase I
L Stewart, MR Redinbo, X Qiu, WGJ Hol, JJ Champoux
Science 279 (5356), 1534-1541, 1998
7871998
Alleviating cancer drug toxicity by inhibiting a bacterial enzyme
BD Wallace, H Wang, KT Lane, JE Scott, J Orans, JS Koo, M Venkatesh, ...
Science 330 (6005), 831-835, 2010
6252010
Crystal structure of an ancient protein: evolution by conformational epistasis
EA Ortlund, JT Bridgham, MR Redinbo, JW Thornton
Science 317 (5844), 1544-1548, 2007
4192007
Regulation of cyp3a gene transcription by the pregnane x receptor
B Goodwin, MR Redinbo, SA Kliewer
Annual review of pharmacology and toxicology 42 (1), 1-23, 2002
4002002
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4
M Venkatesh, S Mukherjee, H Wang, H Li, K Sun, AP Benechet, Z Qiu, ...
Immunity 41 (2), 296-310, 2014
3952014
2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin,
RE Watkins, JM Maglich, LB Moore, GB Wisely, SM Noble, ...
Biochemistry 42 (6), 1430-1438, 2003
3762003
Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor
RE Watkins, PR Davis-Searles, MH Lambert, MR Redinbo
Journal of molecular biology 331 (4), 815-828, 2003
2292003
Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme
S Bencharit, CL Morton, Y Xue, PM Potter, MR Redinbo
Nature Structural & Molecular Biology 10 (5), 349-356, 2003
2182003
Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole
H Huang, H Wang, M Sinz, M Zoeckler, J Staudinger, MR Redinbo, ...
Oncogene 26 (2), 258-268, 2007
2172007
Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin
JE Chrencik, J Orans, LB Moore, Y Xue, L Peng, JL Collins, GB Wisely, ...
Molecular Endocrinology 19 (5), 1125-1134, 2005
2102005
Keynote review: Mammalian carboxylesterases: From drug targets to protein therapeutics
MR Redinbo, PM Potter
Drug discovery today 10 (5), 313-325, 2005
2102005
The role of the microbiome in cancer development and therapy
AP Bhatt, MR Redinbo, SJ Bultman
CA: a cancer journal for clinicians 67 (4), 326-344, 2017
2092017
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
G Schaaf, EA Ortlund, KR Tyeryar, CJ Mousley, KE Ile, TA Garrett, J Ren, ...
Molecular cell 29 (2), 191-206, 2008
2082008
Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP
EA Ortlund, Y Lee, IH Solomon, JM Hager, R Safi, Y Choi, Z Guan, ...
Nature structural & molecular biology 12 (4), 357-363, 2005
1962005
Structural insights into CPT-11 activation by mammalian carboxylesterases
S Bencharit, CL Morton, EL Howard-Williams, MK Danks, PM Potter, ...
Nature structural biology 9 (5), 337-342, 2002
1952002
Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7
MJ Miley, AK Zielinska, JE Keenan, SM Bratton, A Radominska-Pandya, ...
Journal of molecular biology 369 (2), 498-511, 2007
1892007
Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA
MR Redinbo, JJ Champoux, WGJ Hol
Biochemistry 39 (23), 6832-6840, 2000
1892000
Plastocyanin: structural and functional analysis
MR Redinbo, TO Yeates, S Merchant
Journal of bioenergetics and biomembranes 26 (1), 49-66, 1994
1871994
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Articles 1–20