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Lu Huang
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Update of TTD: therapeutic target database
F Zhu, BC Han, P Kumar, XH Liu, XH Ma, XN Wei, L Huang, YF Guo, ...
Nucleic acids research 38 (suppl_1), D787-D791, 2010
3152010
Combination therapy and the evolution of resistance: the theoretical merits of synergism and antagonism in cancer
EC Saputra, L Huang, Y Chen, L Tucker-Kellogg
Cancer research 78 (9), 2419-2431, 2018
852018
In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors
FXR Sutandy, S Ebersberger, L Huang, A Busch, M Bach, HS Kang, ...
Genome research 28 (5), 699-713, 2018
712018
Predicting drug combination index and simulating the network-regulation dynamics by mathematical modeling of drug-targeted EGFR-ERK signaling pathway
L Huang, Y Jiang, Y Chen
Scientific reports 7 (1), 40752, 2017
692017
Integrative network modeling reveals mechanisms underlying T cell exhaustion
H Bolouri, M Young, J Beilke, R Johnson, B Fox, L Huang, CC Santini, ...
Scientific reports 10 (1), 1915, 2020
242020
Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin
L Huang, CQ Pan, B Li, L Tucker-Kellogg, B Tidor, Y Chen, BC Low
PLoS One 6 (8), e22933, 2011
222011
Virtual populations for quantitative systems pharmacology models
Y Cheng, R Straube, AE Alnaif, L Huang, TA Leil, BJ Schmidt
Systems Medicine, 129-179, 2022
182022
From cold to hot: changing perceptions and future opportunities for quantitative systems pharmacology modeling in cancer immunotherapy
V Lemaire, D Bassen, M Reed, R Song, S Khalili, YT Lien, L Huang, ...
Clinical Pharmacology & Therapeutics 113 (5), 963-972, 2023
82023
A perspective on the current use of the phase distribution model for predicting milk‐to‐plasma drug concentration ratio
M Zhang, C Sychterz, M Chang, L Huang, BJ Schmidt, L Gaohua
CPT: Pharmacometrics & Systems Pharmacology 11 (12), 1547-1551, 2022
2022
Synergistic drug combinations promote expansion of partially-resistant subpopulations in computational modeling of cancer heterogeneity and graded plasticity
EC Saputra, L Huang, L Tucker-Kellogg
Cancer Research 78 (13_Supplement), 1185-1185, 2018
2018
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