Update of TTD: therapeutic target database F Zhu, BC Han, P Kumar, XH Liu, XH Ma, XN Wei, L Huang, YF Guo, ... Nucleic acids research 38 (suppl_1), D787-D791, 2010 | 327 | 2010 |
Combination therapy and the evolution of resistance: the theoretical merits of synergism and antagonism in cancer EC Saputra, L Huang, Y Chen, L Tucker-Kellogg Cancer research 78 (9), 2419-2431, 2018 | 93 | 2018 |
In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors FXR Sutandy, S Ebersberger, L Huang, A Busch, M Bach, HS Kang, ... Genome research 28 (5), 699-713, 2018 | 78 | 2018 |
Predicting drug combination index and simulating the network-regulation dynamics by mathematical modeling of drug-targeted EGFR-ERK signaling pathway L Huang, Y Jiang, Y Chen Scientific reports 7 (1), 40752, 2017 | 76 | 2017 |
Virtual populations for quantitative systems pharmacology models Y Cheng, R Straube, AE Alnaif, L Huang, TA Leil, BJ Schmidt Systems Medicine, 129-179, 2022 | 32 | 2022 |
Integrative network modeling reveals mechanisms underlying T cell exhaustion H Bolouri, M Young, J Beilke, R Johnson, B Fox, L Huang, CC Santini, ... Scientific reports 10 (1), 1915, 2020 | 27 | 2020 |
Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin L Huang, CQ Pan, B Li, L Tucker-Kellogg, B Tidor, Y Chen, BC Low Plos one 6 (8), e22933, 2011 | 22 | 2011 |
From cold to hot: changing perceptions and future opportunities for quantitative systems pharmacology modeling in cancer immunotherapy V Lemaire, D Bassen, M Reed, R Song, S Khalili, YT Lien, L Huang, ... Clinical Pharmacology & Therapeutics 113 (5), 963-972, 2023 | 12 | 2023 |
A perspective on the current use of the phase distribution model for predicting milk‐to‐plasma drug concentration ratio M Zhang, C Sychterz, M Chang, L Huang, BJ Schmidt, L Gaohua CPT: Pharmacometrics & Systems Pharmacology 11 (12), 1547-1551, 2022 | 1 | 2022 |
Synergistic drug combinations promote expansion of partially-resistant subpopulations in computational modeling of cancer heterogeneity and graded plasticity EC Saputra, L Huang, L Tucker-Kellogg Cancer Research 78 (13_Supplement), 1185-1185, 2018 | | 2018 |