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Christopher T Chan
Christopher T Chan
Postdoctoral Fellow, Massachusetts General Hospital, Harvard Medical School
Dirección de correo verificada de mgh.harvard.edu
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Sleep modulates haematopoiesis and protects against atherosclerosis
CS McAlpine, MG Kiss, S Rattik, S He, A Vassalli, C Valet, A Anzai, ...
Nature 566 (7744), 383-387, 2019
3422019
Obligatory role for B cells in the development of angiotensin II–dependent hypertension
CT Chan, CG Sobey, M Lieu, D Ferens, MM Kett, H Diep, HA Kim, ...
Hypertension 66 (5), 1023-1033, 2015
2352015
Immune cell infiltration in malignant middle cerebral artery infarction: comparison with transient cerebral ischemia
HX Chu, HA Kim, S Lee, JP Moore, CT Chan, A Vinh, M Gelderblom, ...
Journal of Cerebral Blood Flow & Metabolism 34 (3), 450-459, 2014
2272014
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension
SM Krishnan, YH Ling, BM Huuskes, DM Ferens, N Saini, CT Chan, ...
Cardiovascular Research 115 (4), 776-787, 2019
2142019
The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes
A Anzai, JL Choi, S He, AM Fenn, M Nairz, S Rattik, CS McAlpine, ...
Journal of Experimental Medicine 214 (11), 3293-3310, 2017
1852017
Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice
SM Krishnan, JK Dowling, YH Ling, H Diep, CT Chan, D Ferens, MM Kett, ...
British journal of pharmacology 173 (4), 752-765, 2016
1822016
Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease
CS McAlpine, J Park, A Griciuc, E Kim, SH Choi, Y Iwamoto, MG Kiss, ...
Nature 595 (7869), 701-706, 2021
1812021
M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure
JP Moore, A Vinh, KL Tuck, S Sakkal, SM Krishnan, CT Chan, M Lieu, ...
American Journal of Physiology-Heart and Circulatory Physiology 309 (5 …, 2015
1482015
Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease
S He, F Kahles, S Rattik, M Nairz, CS McAlpine, A Anzai, D Selgrade, ...
Nature 566 (7742), 115-119, 2019
1402019
Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
EE To, R Vlahos, R Luong, ML Halls, PC Reading, PT King, C Chan, ...
Nature communications 8 (1), 69, 2017
1322017
Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice
CT Chan, JP Moore, K Budzyn, E Guida, H Diep, A Vinh, ES Jones, ...
Hypertension 60 (5), 1207-1212, 2012
1322012
Brain motor and fear circuits regulate leukocytes during acute stress
WC Poller, J Downey, AA Mooslechner, N Khan, L Li, CT Chan, ...
Nature 607 (7919), 578-584, 2022
802022
Acute or delayed systemic administration of human amnion epithelial cells improves outcomes in experimental stroke
MA Evans, R Lim, HA Kim, HX Chu, CV Gardiner-Mann, KWE Taylor, ...
Stroke 49 (3), 700-709, 2018
672018
Advanced atherosclerosis is associated with inflammation, vascular dysfunction and oxidative stress, but not hypertension
QN Dinh, S Chrissobolis, H Diep, CT Chan, D Ferens, GR Drummond, ...
Pharmacological research 116, 70-76, 2017
562017
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension
YH Ling, SM Krishnan, CT Chan, H Diep, D Ferens, J Chin-Dusting, ...
Pharmacological research 116, 77-86, 2017
552017
Antibodies in the pathogenesis of hypertension
CT Chan, M Lieu, BH Toh, TS Kyaw, A Bobik, CG Sobey, GR Drummond
BioMed Research International 2014, 2014
532014
Monocytes re-enter the bone marrow during fasting and alter the host response to infection
H Janssen, F Kahles, D Liu, J Downey, LL Koekkoek, V Roudko, ...
Immunity 56 (4), 783-796. e7, 2023
462023
Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis
A Anzai, JE Mindur, L Halle, S Sano, JL Choi, S He, CS McAlpine, ...
Journal of Experimental Medicine 216 (2), 369-383, 2019
452019
Sleep exerts lasting effects on hematopoietic stem cell function and diversity
CS McAlpine, MG Kiss, FM Zuraikat, D Cheek, G Schiroli, H Amatullah, ...
Journal of Experimental Medicine 219 (11), e20220081, 2022
312022
Liver X receptors are required for thymic resilience and T cell output
CT Chan, AM Fenn, NK Harder, JE Mindur, CS McAlpine, J Patel, C Valet, ...
Journal of Experimental Medicine 217 (10), 2020
272020
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