Margarita Vega-Holm
Margarita Vega-Holm
Universidad de Sevilla, Departamento de Química Orgánica y Farmacéutica
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Isoprenyl-thiourea and urea derivatives as new farnesyl diphosphate analogues: Synthesis and in vitro antimicrobial and cytotoxic activities
JM Vega-Pérez, I Periñán, M Argandoña, M Vega-Holm, C Palo-Nieto, ...
European journal of medicinal chemistry 58, 591-612, 2012
GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery
G Carullo, S Mazzotta, M Vega-Holm, F Iglesias-Guerra, JM Vega-Pérez, ...
Journal of Medicinal Chemistry 64 (8), 4312-4332, 2021
New 4-acyl-1-phenylaminocarbonyl-2-phenylpiperazine derivatives as potential inhibitors of adenovirus infection. synthesis, biological evaluation, and structure–activity …
J Sánchez-Céspedes, P Martínez-Aguado, M Vega-Holm, ...
Journal of medicinal chemistry 59 (11), 5432-5448, 2016
Stereoselective synthesis of oxiranes using oxazolidines derived from 2-amino-2-deoxy-d-allose as chiral auxiliaries
JM Vega-Pérez, M Vega, E Blanco, F Iglesias-Guerra
Tetrahedron: Asymmetry 12 (22), 3189-3203, 2001
Aziridines from alkenyl-β-D-galactopyranoside derivatives: Stereoselective synthesis and in vitro selective anticancer activity
JM Vega-Pérez, C Palo-Nieto, M Vega-Holm, P Góngora-Vargas, ...
European journal of medicinal chemistry 70, 380-392, 2013
Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agents
S Mazzotta, JA Marrugal-Lorenzo, M Vega-Holm, A Serna-Gallego, ...
European Journal of Medicinal Chemistry 185, 111840, 2020
New mannose-derived ketones as organocatalysts for enantioselective dioxirane-mediated epoxidation of arylalkenes. Part 3: Chiral ketones from sugars
JM Vega-Pérez, I Periñán, M Vega-Holm, C Palo-Nieto, F Iglesias-Guerra
Tetrahedron 67 (37), 7057-7065, 2011
Stereoselective epoxidation of alkenylidene acetals derived from carbohydrates with d-allo, d-altro, d-galacto, d-gluco and d-xylo configurations
JM Vega-Pérez, M Vega, E Blanco, F Iglesias-Guerra
Tetrahedron: Asymmetry 18 (15), 1850-1867, 2007
New Oleoyl Hybrids of Natural Antioxidants: Synthesis and In Vitro Evaluation as Inducers of Apoptosis in Colorectal Cancer Cells
G Carullo, S Mazzotta, A Koch, KM Hartmann, O Friedrich, DF Gilbert, ...
Antioxidants 9 (11), 1077, 2020
Stereoselective cyclopropanation of unsaturated acetals, using carbohydrates with d-gluco, l-rhamno and d-xylo configurations as chiral auxiliaries
JM Vega-Pérez, I Periñán, M Vega, F Iglesias-Guerra
Tetrahedron: Asymmetry 19 (14), 1720-1729, 2008
Stereoselective synthesis of oxiranes as a source of isoserine analogues using d-glucosamine and d-glucose derivatives as chiral templates
JM Vega-Pérez, M Vega, E Blanco, F Iglesias-Guerra
Tetrahedron: Asymmetry 15 (22), 3617-3633, 2004
A general method for synthesis of alkyl 2-N-substituted and 2-N, N-disubstituted d-altrosamines
JM Vega-Pérez, JI Candela, M Vega, F Iglesias-Guerra
Carbohydrate research 279, C5-C8, 1995
Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter …
S Mazzotta, T Cebrero-Cangueiro, L Frattaruolo, M Vega-Holm, ...
Bioorganic & Medicinal Chemistry Letters, 127411, 2020
Alkenyl β-d-galactopyranoside derivatives as efficient chiral templates in stereoselective cyclopropanation and epoxidation reactions
JM Vega-Pérez, I Periñán, C Palo-Nieto, M Vega-Holm, F Iglesias-Guerra
Tetrahedron: Asymmetry 21 (1), 81-95, 2010
Synthesis of new carbohydrate-derived ketones as organocatalysts in the enantioselective epoxidation of arylalkenes. Part 2: Chiral ketones from sugars
JM Vega-Pérez, M Vega-Holm, I Periñán, C Palo-Nieto, F Iglesias-Guerra
Tetrahedron 67 (2), 364-372, 2011
Design, Synthesis and In Vitro Experimental Validation of Novel TRPV4 Antagonists Inspired by Labdane Diterpenes
S Mazzotta, G Carullo, A Schiano Moriello, P Amodeo, V Di Marzo, ...
Marine drugs 18 (10), 519, 2020
Stereoselective synthesis of oxazolidines from 2-amino-2-deoxy-d-allose derivatives and their reactivity with nucleophiles
JM Vega-Pérez, M Vega, E Blanco, F Iglesias-Guerra
Tetrahedron: Asymmetry 12 (1), 135-147, 2001
Synthesis of New Chiral Ketones from D‐Glucose Derivatives and Their Use in the Enantioselective Epoxidation of Arylalkenes
JM Vega‐Pérez, M Vega Holm, ML Martínez, E Blanco, F Iglesias‐Guerra
European Journal of Organic Chemistry 2009 (34), 6018-6009, 2009
Serinol-Based Benzoic Acid Esters as New Scaffolds for the Development of Adenovirus Infection Inhibitors: Design, Synthesis, and In Vitro Biological Evaluation
S Mazzotta, J Berastegui-Cabrera, G Carullo, M Vega-Holm, ...
ACS Infectious Diseases, 2020
Design, synthesis and in vitro biological evaluation of a novel class of anti-adenovirus agents based on 3-amino-1, 2-propanediol
S Mazzotta, J Berastegui-Cabrera, M Vega-Holm, ...
Bioorganic Chemistry 114, 105095, 2021
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