Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity D Tello, E Balsa, B Acosta-Iborra, E Fuertes-Yebra, A Elorza, Á Ordóñez, ... Cell metabolism 14 (6), 768-779, 2011 | 340 | 2011 |
HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5 A Elorza, I Soro-Arnáiz, F Meléndez-Rodríguez, V Rodríguez-Vaello, ... Molecular cell 48 (5), 681-691, 2012 | 216 | 2012 |
Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-γ production through the HIF-1α transcription factor B Acosta-Iborra, A Elorza, IM Olazabal, NB Martín-Cofreces, S Martin-Puig, ... The Journal of Immunology 182 (5), 3155-3164, 2009 | 116 | 2009 |
The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress A Anedda, E López-Bernardo, B Acosta-Iborra, MS Suleiman, ... Free radical biology and medicine 61, 395-407, 2013 | 98 | 2013 |
Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase E Temes, S Martín-Puig, B Acosta-Iborra, MC Castellanos, ... Journal of Biological Chemistry 280 (25), 24238-24244, 2005 | 66 | 2005 |
4-Hydroxynonenal induces Nrf2-mediated UCP3 upregulation in mouse cardiomyocytes E López-Bernardo, A Anedda, P Sánchez-Pérez, B Acosta-Iborra, ... Free Radical Biology and Medicine 88, 427-438, 2015 | 53 | 2015 |
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia M Tiana, B Acosta-Iborra, L Puente-Santamaría, P Hernansanz-Agustin, ... Nucleic acids research 46 (1), 120-133, 2018 | 51 | 2018 |
CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110 JM Domínguez, G Pérez-Chacón, MJ Guillén, MJ Muñoz-Alonso, ... Journal of Hematology & Oncology 13, 1-15, 2020 | 17 | 2020 |
Metabolic labeling of RNA uncovers the contribution of transcription and decay rates on hypoxia-induced changes in RNA levels M Tiana, B Acosta-Iborra, R Hernández, C Galiana, ... RNA 26 (8), 1006-1022, 2020 | 15 | 2020 |
Mutant versions of von Hippel-Lindau (VHL) can protect HIF1α from SART1-mediated degradation in clear-cell renal cell carcinoma A Ordonez-Navadijo, E Fuertes-Yebra, B Acosta-Iborra, E Balsa, A Elorza, ... Oncogene 35 (5), 587-594, 2016 | 13 | 2016 |
Hypoxia compensates cell cycle arrest with progenitor differentiation during angiogenesis B Acosta‐Iborra, M Tiana, L Maeso‐Alonso, R Hernández‐Sierra, ... The FASEB Journal 34 (5), 6654-6674, 2020 | 9 | 2020 |
Myeloid hypoxia-inducible factors in inflammatory diseases J Aragones, A Elorza, B Acosta-Iborra, MO Landazuri Critical Reviews™ in Immunology 31 (1), 2011 | 9 | 2011 |
An exploration of vascular cell development in mouse embryoid bodies under hypoxia through single cell RNA-seq B Acosta-Iborra, L Puente-Santamaría, Y Berrouayel, L del Peso, ... | | 2024 |
The mitotic cancer target plk1 modulates mouse endothelial homeostasis and in vitro angiogenesis M González-Ávarez, J Bandera, B Acosta-Iborra, MA García-Cabezas, ... | | 2023 |
The mitotic regulator PLK1 modulates mouse endothelial homeostasis and in vitro angiogenesis M González-Ávarez, J Bandera, B Acosta-Iborra, MA García-Cabezas, ... | | 2022 |
UCP3 upregulation in response to 4-hydroxynonenal is mediated by Nrf2 in mouse cardiomyocytes E López-Bernardo, A Anedda, P Sánchez-Pérez, B Acosta-Iborra, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics, e79, 2016 | | 2016 |
Uncoupling protein UCP3 up-regulation during cardioplegia-induced ischemia in the human heart E López-Bernardo, A Anedda, B Acosta-Iborra, C Vaca, J Salamanca, ... BBA-Bioenergetics, S43, 2012 | | 2012 |
Induction of uncoupling protein UCP3 by hydrogen peroxide increases survival in cardiac muscle cells: Implication of the antioxidant transcription factor Nrf2 A Anedda, B Acosta-Iborra, E López-Bernardo, C Vaca, MO Landázuri, ... BBA-Bioenergetics, S40-S41, 2012 | | 2012 |
Hydrogen peroxide induces the expression of uncoupling protein UCP3 in mouse cardiac muscle cells: a survival mechanism mediated by the transcription factor Nrf2 A Anedda, B Acosta-Iborra, E Lóez-Bernardo, C Vaca, MO Landázuri, ... Free Radical Biology and Medicine, S235-S236, 2012 | | 2012 |
La hipoxia induce la activación de los macrófagos potenciando la fagocitosis y la presentación antigénica, a través de la producción de IFN-gamma, mediada por el factor de … B Acosta Iborra | | 2009 |