The comprehensive antibiotic resistance database AG McArthur, N Waglechner, F Nizam, A Yan, MA Azad, AJ Baylay, ... Antimicrobial agents and chemotherapy 57 (7), 3348-3357, 2013 | 1108 | 2013 |
The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism P Spanogiannopoulos, EN Bess, RN Carmody, PJ Turnbaugh Nature Reviews Microbiology 14 (5), 273, 2016 | 383 | 2016 |
The tetracycline resistome M Thaker, P Spanogiannopoulos, GD Wright Cellular and Molecular Life Sciences 67 (3), 419-431, 2010 | 278 | 2010 |
Identifying producers of antibacterial compounds by screening for antibiotic resistance MN Thaker, W Wang, P Spanogiannopoulos, N Waglechner, AM King, ... Nature biotechnology 31 (10), 922-927, 2013 | 153 | 2013 |
Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance PJ Stogios, P Spanogiannopoulos, E Evdokimova, O Egorova, T Shakya, ... Biochemical Journal 454 (2), 191-200, 2013 | 42 | 2013 |
A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria P Spanogiannopoulos, N Waglechner, K Koteva, GD Wright Proceedings of the National Academy of Sciences 111 (19), 7102-7107, 2014 | 36 | 2014 |
Characterization of a rifampin-inactivating glycosyltransferase from a screen of environmental actinomycetes P Spanogiannopoulos, M Thaker, K Koteva, N Waglechner, GD Wright Antimicrobial agents and chemotherapy 56 (10), 5061-5069, 2012 | 36 | 2012 |
Cooking shapes the structure and function of the gut microbiome RN Carmody, JE Bisanz, BP Bowen, CF Maurice, S Lyalina, KB Louie, ... Nature microbiology 4 (12), 2052-2063, 2019 | 33 | 2019 |
Rifampin phosphotransferase is an unusual antibiotic resistance kinase PJ Stogios, G Cox, P Spanogiannopoulos, MC Pillon, N Waglechner, ... Nature communications 7 (1), 1-12, 2016 | 26 | 2016 |
How to determine the role of the microbiome in drug disposition JE Bisanz, P Spanogiannopoulos, LM Pieper, AE Bustion, PJ Turnbaugh Drug Metabolism and Disposition 46 (11), 1588-1595, 2018 | 21 | 2018 |
Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria EN Bess, JE Bisanz, F Yarza, A Bustion, BE Rich, X Li, S Kitamura, ... Nature microbiology 5 (1), 56-66, 2020 | 15 | 2020 |
Broad collateral damage of drugs against the gut microbiome P Spanogiannopoulos, PJ Turnbaugh Nature Reviews Gastroenterology & Hepatology 15 (8), 457-458, 2018 | 11 | 2018 |
The genetic basis for the cooperative bioactivation of plant lignans by a human gut bacterial consortium EN Bess, JE Bisanz, P Spanogiannopoulos, QY Ang, A Bustion, ... bioRxiv, 357640, 2018 | 10 | 2018 |
Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives L Zou, P Spanogiannopoulos, LM Pieper, HC Chien, W Cai, N Khuri, ... Proceedings of the National Academy of Sciences 117 (27), 16009-16018, 2020 | 5 | 2020 |
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiota KN Lam, P Spanogiannopoulos, P Soto-Perez, M Alexander, MJ Nalley, ... bioRxiv, 2020 | 3 | 2020 |
Drug resistant gut bacteria mimic a host mechanism for anticancer drug clearance P Spanogiannopoulos, PH Bradley, J Melamed, YNA Malig, KN Lam, ... BioRxiv, 820084, 2019 | | 2019 |
The Metabolism of Fluoropyrimidine Anticancer Drugs by the Human Gut Microbiome P Spanogiannopoulos, AD Patteron, PJ Turnbaugh The FASEB Journal 32, 534.22-534.22, 2018 | | 2018 |
INTERACTIONS OF AZO DYES COMMONLY USED IN ORAL DRUG PRODUCTS WITH THE ORGANIC ANION TRANSPORTING PEPTIDE 2B1 AND HUMAN GUT BACTERIA. L Zou, P Spanogiannopoulos, Z Ni, E Tsakalozou, L Zhang, P Turnbaugh, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S7-S7, 2018 | | 2018 |
Discovery of a bacterial gene in the gut microbiome encoding metabolism of dietary lignans E Bess, J Bisanz, P Spanogiannopoulos, E Waligurski, P Turnbaugh ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Strategies to investigate the xenobiotic-metabolizing capabilities of the human gut microbiome E Bess, J Bisanz, P Spanogiannopoulos, P Turnbaugh ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |