| Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ... Science 324 (5933), 1457-1461, 2009 | 3337 | 2009 |
| SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth T Porstmann, CR Santos, B Griffiths, M Cully, M Wu, S Leevers, ... Cell metabolism 8 (3), 224-236, 2008 | 1438 | 2008 |
| Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations PJ Pollard, JJ Briere, NA Alam, J Barwell, E Barclay, NC Wortham, T Hunt, ... Human molecular genetics 14 (15), 2231-2239, 2005 | 986 | 2005 |
| Causes and consequences of tumour acidity and implications for treatment M Stubbs, PMJ McSheehy, JR Griffiths, CL Bashford Molecular medicine today 6 (1), 15-19, 2000 | 921 | 2000 |
| Imaging biomarker roadmap for cancer studies JPB O'Connor, EO Aboagye, JE Adams, HJWL Aerts, SF Barrington, ... Nature reviews Clinical oncology 14 (3), 169-186, 2017 | 899 | 2017 |
| Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy FA Howe, SJ Barton, SA Cudlip, M Stubbs, DE Saunders, M Murphy, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2003 | 721 | 2003 |
| The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis CE Massie, A Lynch, A Ramos‐Montoya, J Boren, R Stark, L Fazli, ... The EMBO journal 30 (13), 2719-2733, 2011 | 662 | 2011 |
| The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations MO Leach, KM Brindle, JL Evelhoch, JR Griffiths, MR Horsman, A Jackson, ... British journal of cancer 92 (9), 1599-1610, 2005 | 599 | 2005 |
| PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP T Porstmann, B Griffiths, YL Chung, O Delpuech, JR Griffiths, J Downward, ... Oncogene 24 (43), 6465-6481, 2005 | 492 | 2005 |
| Dynamic asymmetry of phosphocreatine concentration and O2 uptake between the on‐ and off‐transients of moderate‐ and high‐intensity exercise in humans HB Rossiter, SA Ward, JM Kowalchuk, FA Howe, JR Griffiths, BJ Whipp The Journal of physiology 541 (3), 991-1002, 2002 | 435 | 2002 |
| Inferences from pulmonary O2 uptake with respect to intramuscular [phosphocreatine] kinetics during moderate exercise in humans HB Rossiter, SA Ward, VL Doyle, FA Howe, JR Griffiths, BJ Whipp The Journal of physiology 518 (3), 921-932, 1999 | 374 | 1999 |
| S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate PA Tyrakis, A Palazon, D Macias, KL Lee, AT Phan, P Veliça, J You, ... Nature 540 (7632), 236-241, 2016 | 305 | 2016 |
| Application of magnetic resonance neurography in the evaluation of patients with peripheral nerve pathology AG Filler, M Kliot, FA Howe, CE Hayes, DE Saunders, R Goodkin, BA Bell, ... Journal of neurosurgery 85 (2), 299-309, 1996 | 295 | 1996 |
| Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra AR Tate, J Underwood, DM Acosta, M Juliŕ‐Sapé, C Majós, ... NMR in Biomedicine 19 (4), 411-434, 2006 | 278 | 2006 |
| Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous 19F and 31P probes ASE Ojugo, PMJ McSheehy, DJO McIntyre, C McCoy, M Stubbs, ... NMR in Biomedicine: An International Journal Devoted to the Development and …, 1999 | 262 | 1999 |
| RF coils for MRI JT Vaughan, JR Griffiths John Wiley & Sons, 2012 | 249 | 2012 |
| Magnetic resonance neurography AG Filler, M Kliot, HR Winn, JS Tsuruda, CE Hayes, FA Howe, JR Griffiths, ... The Lancet 341 (8846), 659-661, 1993 | 249 | 1993 |
| Magnetic resonance neurography FA Howe, AG Filler, BA Bell, JR Griffiths Magnetic resonance in medicine 28 (2), 328-338, 1992 | 249 | 1992 |
| Effects of prior exercise on oxygen uptake and phosphocreatine kinetics during high‐intensity knee‐extension exercise in humans HB Rossiter, SA Ward, JM Kowalchuk, FA Howe, JR Griffiths, BJ Whipp The Journal of physiology 537 (1), 291-303, 2001 | 246 | 2001 |
| Automated classification of short echo time in in vivo 1H brain tumor spectra: A multicenter study AR Tate, C Majós, A Moreno, FA Howe, JR Griffiths, C Arús Magnetic Resonance in Medicine: An Official Journal of the International …, 2003 | 244 | 2003 |
Franklyn Arron HOWEProfessor of Magnetic Resonance Imaging, St George's, University of LondonVerified email at sgul.ac.uk
