Mucins in the pathogenesis of breast cancer: implications in diagnosis, prognosis and therapy P Mukhopadhyay, S Chakraborty, MP Ponnusamy, I Lakshmanan, M Jain, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1815 (2), 224-240, 2011 | 237 | 2011 |
MUC16 as a novel target for cancer therapy A Aithal, S Rauth, P Kshirsagar, A Shah, I Lakshmanan, WM Junker, ... Expert opinion on therapeutic targets 22 (8), 675-686, 2018 | 194 | 2018 |
MUC4 mucin-induced epithelial to mesenchymal transition: a novel mechanism for metastasis of human ovarian cancer cells MP Ponnusamy, I Lakshmanan, M Jain, S Das, S Chakraborty, P Dey, ... Oncogene 29 (42), 5741-5754, 2010 | 161 | 2010 |
MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells I Lakshmanan, MP Ponnusamy, S Das, S Chakraborty, D Haridas, ... Oncogene 31 (7), 805-817, 2012 | 156 | 2012 |
Pathobiological implications of MUC16 expression in pancreatic cancer D Haridas, S Chakraborty, MP Ponnusamy, I Lakshmanan, S Rachagani, ... PloS one 6 (10), e26839, 2011 | 154 | 2011 |
MUC16: molecular analysis and its functional implications in benign and malignant conditions D Haridas, MP Ponnusamy, S Chugh, I Lakshmanan, P Seshacharyulu, ... The FASEB Journal 28 (10), 4183-4199, 2014 | 153 | 2014 |
Mucins in lung cancer: diagnostic, prognostic, and therapeutic implications I Lakshmanan, MP Ponnusamy, MA Macha, D Haridas, PD Majhi, S Kaur, ... Journal of Thoracic Oncology 10 (1), 19-27, 2015 | 136 | 2015 |
Pancreatic tumor microenvironment factor promotes cancer stemness via SPP1–CD44 Axis P Nallasamy, RK Nimmakayala, S Karmakar, F Leon, P Seshacharyulu, ... Gastroenterology 161 (6), 1998-2013. e7, 2021 | 122 | 2021 |
Protocol for apoptosis assay by flow cytometry using annexin V staining method I Lakshmanan, SK Batra Bio-protocol 3 (6), e374-e374, 2013 | 118 | 2013 |
Molecular implications of MUC5AC-CD44 axis in colorectal cancer progression and chemoresistance R Pothuraju, S Rachagani, SR Krishn, S Chaudhary, RK Nimmakayala, ... Molecular cancer 19, 1-14, 2020 | 107 | 2020 |
Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells S Das, S Rachagani, MP Torres-Gonzalez, I Lakshmanan, PD Majhi, ... Oncotarget 6 (8), 5772, 2015 | 89 | 2015 |
Cigarette smoke induces stem cell features of pancreatic cancer cells via PAF1 RK Nimmakayala, P Seshacharyulu, I Lakshmanan, S Rachagani, ... Gastroenterology 155 (3), 892-908. e6, 2018 | 84 | 2018 |
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation CB Gurumurthy, AR O’brien, RM Quadros, J Adams, P Alcaide, S Ayabe, ... Genome biology 20 (1), 1-14, 2019 | 81 | 2019 |
MUC16 regulates TSPYL5 for lung cancer cell growth and chemoresistance by suppressing p53 I Lakshmanan, S Salfity, P Seshacharyulu, S Rachagani, A Thomas, ... Clinical Cancer Research 23 (14), 3906-3917, 2017 | 79 | 2017 |
RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment AL Hein, CM Post, YM Sheinin, I Lakshmanan, A Natarajan, CA Enke, ... Oncogene 35 (49), 6319-6329, 2016 | 79 | 2016 |
MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism S Muniyan, D Haridas, S Chugh, S Rachagani, I Lakshmanan, S Gupta, ... Genes & cancer 7 (3-4), 110, 2016 | 78 | 2016 |
MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling I Lakshmanan, S Rachagani, R Hauke, SR Krishn, S Paknikar, ... Oncogene 35 (31), 4112-4121, 2016 | 77 | 2016 |
MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells P Mukhopadhyay, I Lakshmanan, MP Ponnusamy, S Chakraborty, M Jain, ... PloS one 8 (2), e54455, 2013 | 71 | 2013 |
Emerging role of mucins in epithelial to mesenchymal transition M P Ponnusamy, P Seshacharyulu, I Lakshmanan, A P Vaz, S Chugh, ... Current cancer drug targets 13 (9), 945-956, 2013 | 63 | 2013 |
RNA-based therapies: a cog in the wheel of lung cancer defense P Khan, JA Siddiqui, I Lakshmanan, AK Ganti, R Salgia, M Jain, SK Batra, ... Molecular cancer 20, 1-24, 2021 | 59 | 2021 |