TGF-β/BMP proteins as therapeutic targets in renal fibrosis. Where have we arrived after 25 years of trials and tribulations? JM Munoz-Felix, M Gonzalez-Nunez, C Martinez-Salgado, ... Pharmacology & therapeutics 156, 44-58, 2015 | 85 | 2015 |
The ALK-1/Smad1 pathway in cardiovascular physiopathology. A new target for therapy? M González-Núñez, JM Muñoz-Félix, JM López-Novoa Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (10 …, 2013 | 74 | 2013 |
ALK1-Smad1/5 signaling pathway in fibrosis development: friend or foe? JM Muñoz-Félix, M González-Núñez, JM López-Novoa Cytokine & growth factor reviews 24 (6), 523-537, 2013 | 73 | 2013 |
Cancer burden is controlled by mural cell-β3-integrin regulated crosstalk with tumor cells PP Wong, JM Muñoz-Félix, M Hijazi, H Kim, SD Robinson, ... Cell 181 (6), 1346-1363. e21, 2020 | 60 | 2020 |
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth T Lechertier, LE Reynolds, H Kim, AR Pedrosa, J Gómez-Escudero, ... Nature Communications 11 (1), 2810, 2020 | 42 | 2020 |
L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction B Oujo, JM Munoz-Felix, M Arevalo, E Nunez-Gomez, L Perez-Roque, ... PLoS One 9 (10), e110365, 2014 | 38 | 2014 |
The role of endoglin in kidney fibrosis JM Muñoz-Felix, B Oujo, JM Lopez-Novoa Expert reviews in molecular medicine 16, e18, 2014 | 34 | 2014 |
Overcoming the lack of oral availability of cyclic hexapeptides: design of a selective and orally available ligand for the Integrin αvβ3 M Weinmüller, F Rechenmacher, U Kiran Marelli, F Reichart, TG Kapp, ... Angewandte Chemie International Edition 56 (51), 16405-16409, 2017 | 33 | 2017 |
Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro JM Muñoz-Félix, C Cuesta, N Perretta-Tejedor, M Subileau, ... Cellular signalling 28 (9), 1252-1261, 2016 | 32 | 2016 |
ALK1 heterozygosity increases extracellular matrix protein expression, proliferation and migration in fibroblasts JM Munoz-Felix, N Perretta-Tejedor, N Eleno, JM Lopez-Novoa, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (6), 1111-1122, 2014 | 32 | 2014 |
Dual role of pericyte α6β1-integrin in tumour blood vessels LE Reynolds, G D'amico, T Lechertier, A Papachristodoulou, ... Journal of cell science 130 (9), 1583-1595, 2017 | 31 | 2017 |
Impaired erythropoietin synthesis in chronic kidney disease is caused by alterations in extracellular matrix composition G Olmos, JM Muñoz‐Félix, I Mora, AG Müller, MP Ruiz‐Torres, ... Journal of Cellular and Molecular Medicine 22 (1), 302-314, 2018 | 28 | 2018 |
Heterozygous disruption of activin receptor–like kinase 1 is associated with increased renal fibrosis in a mouse model of obstructive nephropathy JM Muñoz-Félix, JM López-Novoa, C Martínez-Salgado Kidney international 85 (2), 319-332, 2014 | 27 | 2014 |
Novel pure αVβ3 integrin antagonists that do not induce receptor extension, prime the receptor, or enhance angiogenesis at low concentrations J Li, Y Fukase, Y Shang, W Zou, JM Muñoz-Félix, L Buitrago, ... ACS Pharmacology & Translational Science 2 (6), 387-401, 2019 | 24 | 2019 |
Overexpression of the short endoglin isoform reduces renal fibrosis and inflammation after unilateral ureteral obstruction JM Munoz-Felix, L Perez-Roque, E Nunez-Gomez, B Oujo, M Arevalo, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (9 …, 2016 | 18 | 2016 |
Cardiotrophin‐1 opposes renal fibrosis in mice: Potential prevention of chronic kidney disease N Perretta‐Tejedor, JM Muñoz‐Félix, A Düwel, Y Quiros‐Luis, ... Acta Physiologica 226 (2), e13247, 2019 | 15 | 2019 |
Improved immunotherapy efficacy by vascular modulation EL Newport, AR Pedrosa, A Njegic, KM Hodivala-Dilke, JM Muñoz-Félix Cancers 13 (20), 5207, 2021 | 14 | 2021 |
Absence of K‐Ras reduces proliferation and migration but increases extracellular matrix synthesis in fibroblasts JM Muñoz‐Félix, I Fuentes‐Calvo, C Cuesta, N Eleno, P Crespo, ... Journal of Cellular Physiology 231 (10), 2224-2235, 2016 | 13 | 2016 |
The Dual Effect of the BMP9–ALK1 Pathway in Blood Vessels: An Opportunity for Cancer Therapy Improvement? B Ayuso-Íñigo, L Méndez-García, M Pericacho, JM Muñoz-Félix Cancers 13 (21), 5412, 2021 | 11 | 2021 |
“Splitting the matrix”: intussusceptive angiogenesis meets MT 1‐MMP G D'Amico, JM Muñoz‐Félix, AR Pedrosa, KM Hodivala‐Dilke EMBO molecular medicine 12 (2), e11663, 2020 | 10 | 2020 |