Georges Janssens
Georges Janssens
Postdoc Researcher, AMC, Amsterdam, The Netherlands
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Limitations and possibilities of small RNA digital gene expression profiling
SEV Linsen, E de Wit, G Janssens, S Heater, L Chapman, RK Parkin, ...
Nature methods 6 (7), 474-476, 2009
Next-generation sequencing in aging research: emerging applications, problems, pitfalls and possible solutions
JP De Magalhães, CE Finch, G Janssens
Ageing research reviews 9 (3), 315-323, 2010
Protein biogenesis machinery is a driver of replicative aging in yeast
GE Janssens, AC Meinema, J Gonzalez, JC Wolters, A Schmidt, V Guryev, ...
elife 4, e08527, 2015
The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource
T Craig, C Smelick, R Tacutu, D Wuttke, SH Wood, H Stanley, G Janssens, ...
Nucleic acids research 43 (D1), D873-D878, 2015
Evidence for the hallmarks of human aging in replicatively aging yeast
GE Janssens, LM Veenhoff
Microbial Cell 3 (7), 263, 2016
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
XX Lin, I Sen, GE Janssens, X Zhou, BR Fonslow, D Edgar, N Stroustrup, ...
Nature communications 9 (1), 1-15, 2018
Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease
YJ Liu, RL McIntyre, GE Janssens, RH Houtkooper
Mechanisms of ageing and development 186, 111212, 2020
Construction and use of a microfluidic dissection platform for long-term imaging of cellular processes in budding yeast
DHEW Huberts, SS Lee, J Gonzalez, GE Janssens, IA Vizcarra, ...
Nature protocols 8 (6), 1019-1027, 2013
The natural variation in lifespans of single yeast cells is related to variation in cell size, ribosomal protein, and division time
GE Janssens, LM Veenhoff
PloS one 11 (12), e0167394, 2016
Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics
IL Rempel, MM Crane, DJ Thaller, A Mishra, DPM Jansen, G Janssens, ...
Elife 8, e48186, 2019
A conserved mito-cytosolic translational balance links two longevity pathways
M Molenaars, GE Janssens, EG Williams, A Jongejan, J Lan, S Rabot, ...
Cell metabolism 31 (3), 549-563. e7, 2020
From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs
RL McIntyre, EG Daniels, M Molenaars, RH Houtkooper, GE Janssens
EMBO molecular medicine 11 (9), e9854, 2019
Disease progression in women with X-linked adrenoleukodystrophy is slow
IC Huffnagel, MGW Dijkgraaf, GE Janssens, M van Weeghel, ...
Orphanet journal of rare diseases 14 (1), 1-15, 2019
Transcriptomics-based screening identifies pharmacological inhibition of Hsp90 as a means to defer aging
GE Janssens, XX Lin, L Millan-Ariño, A Kavšek, I Sen, RI Seinstra, ...
Cell reports 27 (2), 467-480. e6, 2019
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion
YJ Liu, GE Janssens, RL McIntyre, M Molenaars, R Kamble, AW Gao, ...
PLoS genetics 15 (3), e1007633, 2019
Identification of key pathways and metabolic fingerprints of longevity in C. elegans
AW Gao, RL Smith, M Van Weeghel, R Kamble, GE Janssens, ...
Experimental gerontology 113, 128-140, 2018
Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-30
YJ Liu, RL McIntyre, GE Janssens, EG Williams, J Lan, M van Weeghel, ...
Journal of Cell Biology 219 (6), 2020
Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan
S Leupold, G Hubmann, A Litsios, AC Meinema, V Takhaveev, ...
Elife 8, e41046, 2019
HNRNPR variants that impair Homeobox gene expression drive developmental disorders in humans
FA Duijkers, A McDonald, GE Janssens, M Lezzerini, A Jongejan, ...
The American Journal of Human Genetics 104 (6), 1040-1059, 2019
Increased genome instability is not accompanied by sensitivity to DNA damaging agents in aged yeast cells
D Novarina, SN Mavrova, GE Janssens, IL Rempel, LM Veenhoff, ...
DNA repair 54, 1-7, 2017
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Artículos 1–20