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Jérôme Alexandre
Jérôme Alexandre
Université Paris Cité
Dirección de correo verificada de aphp.fr
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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
D Trachootham, J Alexandre, P Huang
Nature reviews Drug discovery 8 (7), 579-591, 2009
53662009
Controlling tumor growth by modulating endogenous production of reactive oxygen species
A Laurent, C Nicco, C Chéreau, C Goulvestre, J Alexandre, A Alves, ...
Cancer research 65 (3), 948-956, 2005
5942005
Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer
E Raymond, J Alexandre, S Faivre, K Vera, E Materman, J Boni, C Leister, ...
Journal of clinical oncology 22 (12), 2336-2347, 2004
5752004
Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species
J Alexandre, Y Hu, W Lu, H Pelicano, P Huang
Cancer research 67 (8), 3512-3517, 2007
4402007
Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel‐induced cancer cell death both in vitro and in vivo
J Alexandre, F Batteux, C Nicco, C Chéreau, A Laurent, L Guillevin, ...
International journal of cancer 119 (1), 41-48, 2006
3872006
Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients
A Yovine, M Riofrio, JY Blay, E Brain, J Alexandre, C Kahatt, A Taamma, ...
Journal of Clinical Oncology 22 (5), 890-899, 2004
3762004
Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study
SM Domchek, S Postel-Vinay, SA Im, YH Park, JP Delord, A Italiano, ...
The Lancet Oncology 21 (9), 1155-1164, 2020
3282020
Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir
J Alexandre, C Nicco, C Chéreau, A Laurent, B Weill, F Goldwasser, ...
Journal of the National Cancer Institute 98 (4), 236-244, 2006
2382006
Sorafenib-Induced Hepatocellular Carcinoma Cell Death Depends on Reactive Oxygen Species Production In Vitro and In Vivo
R Coriat, C Nicco, C Chéreau, O Mir, J Alexandre, S Ropert, B Weill, ...
Molecular cancer therapeutics 11 (10), 2284-2293, 2012
2132012
Pharmacokinetics and toxicity of docetaxel: Role of CYP3A, MDR1, and GST polymorphisms
A Tran, V Jullien, J Alexandre, E Rey, F Rabillon, V Girre, V Dieras, ...
Clinical pharmacology & therapeutics 79 (6), 570-580, 2006
1782006
Evaluation of the nutritional and inflammatory status in cancer patients for the risk assessment of severe haematological toxicity following chemotherapy
J Alexandre, M Gross-Goupil, B Falissard, ML Nguyen, JM Gornet, ...
Annals of Oncology 14 (1), 36-41, 2003
1652003
Randomized phase III trial of irinotecan plus cisplatin compared with paclitaxel plus carboplatin as first-line chemotherapy for ovarian clear cell carcinoma: JGOG3017/GCIG trial
T Sugiyama, A Okamoto, T Enomoto, T Hamano, E Aotani, Y Terao, ...
Journal of clinical oncology 34 (24), 2881-2887, 2016
1362016
Trabectedin in combination with doxorubicin for first-line treatment of advanced uterine or soft-tissue leiomyosarcoma (LMS-02): a non-randomised, multicentre, phase 2 trial
P Pautier, A Floquet, C Chevreau, N Penel, C Guillemet, C Delcambre, ...
The Lancet Oncology 16 (4), 457-464, 2015
1272015
Dimethyl fumarate, a two‐edged drug: current status and future directions
NEB Saidu, N Kavian, K Leroy, C Jacob, C Nicco, F Batteux, J Alexandre
Medicinal research reviews 39 (5), 1923-1952, 2019
1162019
Gynecologic Cancer InterGroup (GCIG) consensus review for mucinous ovarian carcinoma
JA Ledermann, D Luvero, A Shafer, D O’Connor, G Mangili, M Friedlander, ...
International Journal of Gynecologic Cancer 24 (Supp 3), 2014
1132014
Relation between hypermetabolism, cachexia, and survival in cancer patients: a prospective study in 390 cancer patients before initiation of anticancer therapy
C Vazeille, A Jouinot, JP Durand, N Neveux, P Boudou-Rouquette, ...
The American journal of clinical nutrition 105 (5), 1139-1147, 2017
1112017
Preliminary safety and efficacy of first-line pertuzumab combined with trastuzumab and taxane therapy for HER2-positive locally recurrent or metastatic breast cancer (PERUSE)
T Bachelot, E Ciruelos, A Schneeweiss, F Puglisi, T Peretz-Yablonski, ...
Annals of Oncology 30 (5), 766-773, 2019
1072019
Mucinous advanced epithelial ovarian carcinoma: clinical presentation and sensitivity to platinum–paclitaxel-based chemotherapy, the GINECO experience
J Alexandre, I Ray-Coquard, F Selle, A Floquet, P Cottu, B Weber, ...
Annals of oncology 21 (12), 2377-2381, 2010
1042010
Arsenic trioxide exerts antitumor activity through regulatory T cell depletion mediated by oxidative stress in a murine model of colon cancer
A Thomas-Schoemann, F Batteux, C Mongaret, C Nicco, C Chéreau, ...
The Journal of Immunology 189 (11), 5171-5177, 2012
1022012
Stage I non-seminomatous germ-cell tumours of the testis: identification of a subgroup of patients with a very low risk of relapse
J Alexandre, K Fizazi, C Mahe, S Culine, JP Droz, C Théodore, ...
European Journal of Cancer 37 (5), 576-582, 2001
1012001
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